(Q37972741)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Recognition of Streptococcus pneumoniae by the innate immune system (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

main subject

Streptococcus pneumoniae

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

3

Bastian Opitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2

Norbert Suttorp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

publication date

8 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

published in

Cellular Microbiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

460-466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22212419%20AND%20SRC:MED&resulttype=core&format=json

Genetic alteration of capsule type but not PspA type affects accessibility of surface-bound complement and surface antigens of Streptococcus pneumoniae

19 January 2020

cites work

1 reference

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Myeloid differentiation factor 88-dependent signalling controls bacterial growth during colonization and systemic pneumococcal disease in mice.

21 January 2018

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Toll-like receptor 9 acts at an early stage in host defence against pneumococcal infection

21 January 2018

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Cytoplasmic DNA innate immune pathways

21 January 2018

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Stimulation of the intracellular bacterial sensor NOD2 programs dendritic cells to promote interleukin-17 production in human memory T cells

21 January 2018

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Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.

21 January 2018

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NOD-like receptors: role in innate immunity and inflammatory disease

21 January 2018

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Invasive bacterial pathogens exploit TLR-mediated downregulation of tight junction components to facilitate translocation across the epithelium

21 January 2018

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Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.

21 January 2018

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Role played by Toll-like receptors 2 and 4 in lipoteichoic acid-induced lung inflammation and coagulation

21 January 2018

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Role of Toll-like receptors 2 and 4 in pulmonary inflammation and injury induced by pneumolysin in mice

21 January 2018

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Toll-like receptor 2-deficient mice are highly susceptible to Streptococcus pneumoniae meningitis because of reduced bacterial clearing and enhanced inflammation.

21 January 2018

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Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

21 January 2018

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Streptococcus pneumoniae deficient in pneumolysin or autolysin has reduced virulence in meningitis.

21 January 2018

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The NLRP3 inflammasome contributes to brain injury in pneumococcal meningitis and is activated through ATP-dependent lysosomal cathepsin B release

21 January 2018

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The Streptococcus pneumoniae capsule inhibits complement activity and neutrophil phagocytosis by multiple mechanisms

21 January 2018

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Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

21 January 2018

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Streptococcus pneumoniae nasopharyngeal colonization induces type I interferons and interferon-induced gene expression

21 January 2018

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Upper and lower respiratory tract infection by Streptococcus pneumoniae is affected by pneumolysin deficiency and differences in capsule type.

21 January 2018

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The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

21 January 2018

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Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza

21 January 2018

1 reference

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Both innate immunity and type 1 humoral immunity to Streptococcus pneumoniae are mediated by MyD88 but differ in their relative levels of dependence on toll-like receptor 2.

21 January 2018

1 reference

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Innate immunity to pneumococcal infection of the central nervous system depends on toll-like receptor (TLR) 2 and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Role of Caspase-1 in experimental pneumococcal meningitis: Evidence from pharmacologic Caspase inhibition and Caspase-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Toll-like receptor 2 participates in mediation of immune response in experimental pneumococcal meningitis

21 January 2018

1 reference

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MyD88 is required for mounting a robust host immune response to Streptococcus pneumoniae in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Toll-like receptor 2 deficiency delays pneumococcal phagocytosis and impairs oxidative killing by granulocytes

21 January 2018

1 reference

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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

21 January 2018

1 reference

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Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Pneumolysin-induced lung injury is independent of leukocyte trafficking into the alveolar space

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

21 January 2018

1 reference

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Streptococcus pneumoniae: virulence factors and variation

21 January 2018

1 reference

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Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

21 January 2018

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

21 January 2018

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Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

21 January 2018

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Innate immune recognition in infectious and noninfectious diseases of the lung

21 January 2018

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Streptococcus pneumoniae DNA initiates type I interferon signaling in the respiratory tract

21 January 2018

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Innate immunity and the pneumococcus.

21 January 2018

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Pathogenesis, treatment, and prevention of pneumococcal pneumonia

21 January 2018

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The sterile inflammatory response

21 January 2018

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Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.

21 January 2018

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Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia

21 January 2018

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Pneumococci induced TLR- and Rac1-dependent NF-kappaB-recruitment to the IL-8 promoter in lung epithelial cells

21 January 2018

1 reference

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21 January 2018

1 reference

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Lipoteichoic acid (LTA) of Streptococcus pneumoniae and Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP), and CD14, whereas TLR-4 and MD-2 are not involved

21 January 2018

1 reference

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Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

21 January 2018

1 reference

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Innate immune sensing of DNA

21 January 2018

1 reference

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Critical involvement of pneumolysin in production of interleukin-1alpha and caspase-1-dependent cytokines in infection with Streptococcus pneumoniae in vitro: a novel function of pneumolysin in caspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Peptidoglycan: a critical activator of the mammalian immune system during infection and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

The apoptotic response to pneumolysin is Toll-like receptor 4 dependent and protects against pneumococcal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Pyogenic bacterial infections in humans with MyD88 deficiency

21 January 2018

1 reference

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Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis

21 January 2018

1 reference

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Decreased virulence of a pneumolysin-deficient strain of Streptococcus pneumoniae in murine meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

IL-1 Receptor Type 1 Gene-Deficient Mice Demonstrate an Impaired Host Defense Against Pneumococcal Meningitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X

The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1462-5822.2011.01746.X