(Q34800201)

English

7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4.

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

7,3',4'-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4. (English)

1 reference

Europe PubMed Central

4 August 2017

3',4',7-trihydroxyisoflavone

1 reference

ChEBI release 2020-05-28

ultraviolet radiation

0 references

1 reference

based on heuristic

inferred from title

2

object named as

Ki Won Lee

1 reference

Europe PubMed Central

4 August 2017

13

object named as

Hyong Joo Lee

1 reference

Europe PubMed Central

4 August 2017

12

object named as

Ann M Bode

1 reference

Europe PubMed Central

4 August 2017

14

object named as

Zigang Dong

1 reference

Europe PubMed Central

4 August 2017

4

object named as

Sung Keun Jung

1 reference

Europe PubMed Central

4 August 2017

9

object named as

Nam Joo Kang

1 reference

Europe PubMed Central

4 August 2017

3

object named as

Sanguine Byun

1 reference

Europe PubMed Central

4 August 2017

6

object named as

Sung Hwan Lim

1 reference

Europe PubMed Central

4 August 2017

11

object named as

G Tim Bowden

1 reference

Europe PubMed Central

4 August 2017

author name string

Dong Eun Lee

1

1 reference

Europe PubMed Central

4 August 2017

Nury Song

5

1 reference

Europe PubMed Central

4 August 2017

Yong-Seok Heo

7

1 reference

Europe PubMed Central

4 August 2017

Jong Eun Kim

8

1 reference

Europe PubMed Central

4 August 2017

Bo Yeon Kim

10

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

4 March 2011

1 reference

Europe PubMed Central

4 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

4 August 2017

286

1 reference

Europe PubMed Central

4 August 2017

16

1 reference

Europe PubMed Central

4 August 2017

14246-14256

1 reference

Europe PubMed Central

4 August 2017

Photoprotective effect of red ginseng against ultraviolet radiation-induced chronic skin damage in the hairless mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Tpl-2/Cot and COX-2 in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Nondenatured soy extracts reduce UVB-induced skin damage via multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

NIK and Cot cooperate to trigger NF-kappaB p65 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Cyclo-oxygenase-2 plays a critical role in UV-induced skin carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Cot, a novel kinase of histone H3, induces cellular transformation through up-regulation of c-fos transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Role of mitogen-activated protein kinase kinase 4 in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Physiological roles of MKK4 and MKK7: insights from animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-kappaB signaling in human epidermal keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

T-oligo treatment decreases constitutive and UVB-induced COX-2 levels through p53- and NFkappaB-dependent repression of the COX-2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Mechanism of p38 MAP kinase activation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Transgenic cyclooxygenase-2 overexpression sensitizes mouse skin for carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Ultraviolet B(UVB)-induced cox-2 expression in murine skin: an immunohistochemical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Oxidative in vitro metabolism of the soy phytoestrogens daidzein and genistein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Mitogen-activated protein kinase kinase 4 (MKK4).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

COX-2 expression is induced by UVB exposure in human skin: implications for the development of skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077626

8 July 2018

Serine/threonine kinase, Cot/Tpl2, regulates renal cell apoptosis in ischaemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147348

21 January 2018

Myricetin suppresses UVB-induced skin cancer by targeting Fyn.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147348

21 January 2018

Photoprotective effect of isoflavone genistein on ultraviolet B-induced pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147348

21 January 2018

Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147348

21 January 2018

Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.147348

21 January 2018

Protective effects of silymarin against photocarcinogenesis in a mouse skin model

1 reference

https://pubmed.ncbi.nlm.nih.gov/21378167

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.147348

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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