(Q34800371)

4 August 2017

title

Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection (English)

1 reference

4 August 2017

Daniel R Garalde

1

1 reference

4 August 2017

Christopher A Simon

2

1 reference

4 August 2017

Joseph M Dahl

3

1 reference

4 August 2017

Hongyun Wang

4

1 reference

4 August 2017

Mark Akeson

5

1 reference

4 August 2017

Kate R Lieberman

6

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4 August 2017

language of work or name

English

0 references

publication date

28 February 2011

1 reference

Journal of Biological Chemistry

4 August 2017

published in

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4 August 2017

volume

286

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4 August 2017

issue

16

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4 August 2017

page(s)

14480-14492

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Processive replication of single DNA molecules in a nanopore catalyzed by phi29 DNA polymerase

4 August 2017

cites work

1 reference

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Distinct roles of the active-site Mg2+ ligands, Asp882 and Asp705, of DNA polymerase I (Klenow fragment) during the prechemistry conformational transitions

8 July 2018

1 reference

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DNA conformational changes at the primer-template junction regulate the fidelity of replication by DNA polymerase

8 July 2018

1 reference

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Replication of individual DNA molecules under electronic control using a protein nanopore

8 July 2018

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Conformational transitions in DNA polymerase I revealed by single-molecule FRET.

8 July 2018

1 reference

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Electronic control of DNA polymerase binding and unbinding to single DNA molecules

8 July 2018

1 reference

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Sequence-specific detection of individual DNA polymerase complexes in real time using a nanopore

8 July 2018

1 reference

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Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity

8 July 2018

1 reference

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A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution

8 July 2018

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The properties of steric gate mutants reveal different constraints within the active sites of Y-family and A-family DNA polymerases

8 July 2018

1 reference

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Structure and mechanism of DNA polymerases

8 July 2018

1 reference

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Use of 2-aminopurine fluorescence to examine conformational changes during nucleotide incorporation by DNA polymerase I (Klenow fragment).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Discrimination against purine-pyrimidine mispairs in the polymerase active site of DNA polymerase I: a structural explanation

8 July 2018

1 reference

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Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules

8 July 2018

1 reference

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Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site

8 July 2018

1 reference

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Structural and functional insights provided by crystal structures of DNA polymerases and their substrate complexes.

8 July 2018

1 reference

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Kinetic mechanism of DNA polymerase I (Klenow).

8 July 2018

1 reference

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Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3077647

Motions of the fingers subdomain of klentaq1 are fast and not rate limiting: implications for the molecular basis of fidelity in DNA polymerases

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Specific nucleotide binding and rebinding to individual DNA polymerase complexes captured on a nanopore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

On Rereading R. A. Fisher

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Conformational dynamics of DNA polymerase probed with a novel fluorescent DNA base analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

Structural basis for substrate selection by t7 RNA polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.218750

21 January 2018

Identifiers

DOI

10.1074/JBC.M111.218750

1 reference

4 August 2017

1 reference

4 August 2017

1 reference