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Self-complementary AAV vectors; advances and applications
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Self-complementary AAV vectors; advances and applications
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
author name string
Douglas M McCarty
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
publication date
5 August 2008
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
published in
Molecular Therapy
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
volume
16
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
issue
10
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
page(s)
1648-1656
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
cites work
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis
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Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus.
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Differential internalization and nuclear uncoating of self-complementary adeno-associated virus pseudotype vectors as determinants of cardiac cell transduction
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Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors
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Existence of transient functional double-stranded DNA intermediates during recombinant AAV transduction
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Purification of host cell enzymes involved in adeno-associated virus DNA replication
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Complete in vitro reconstitution of adeno-associated virus DNA replication requires the minichromosome maintenance complex proteins
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Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo
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Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison
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Efficient mouse airway transduction following recombination between AAV vectors carrying parts of a larger gene.
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Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction
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Adeno-associated virus of a single-polarity DNA genome is capable of transduction in vivo
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Effects of gamma irradiation on the transduction of dividing and nondividing cells in brain and muscle of rats by adeno-associated virus vectors
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Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiency
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Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo
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Looking into the safety of AAV vectors
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Adeno-associated virus vectors integrate at chromosome breakage sites
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AAV vectors, insertional mutagenesis, and cancer
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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Transduction of hepatocellular carcinoma (HCC) using recombinant adeno-associated virus (rAAV): in vitro and in vivo effects of genotoxic agents
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Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
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AAV vector-mediated reversal of hypoglycemia in canine and murine glycogen storage disease type Ia.
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Single-stranded DNA-protein interactions in canine parvovirus.
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DNA helicase-mediated packaging of adeno-associated virus type 2 genomes into preformed capsids
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The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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based on heuristic
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Adeno-associated virus terminal repeat (TR) mutant generates self-complementary vectors to overcome the rate-limiting step to transduction in vivo
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Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo
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Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity.
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Delivery of MDR1 small interfering RNA by self-complementary recombinant adeno-associated virus vector
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Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
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inferred from DOI database lookup
The packaging capacity of adeno-associated virus (AAV) and the potential for wild-type-plus AAV gene therapy vectors
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice.
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Crossref
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Packaging capacity of adeno-associated virus serotypes: impact of larger genomes on infectivity and postentry steps
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Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction
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Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2.
1 reference
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based on heuristic
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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
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High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus serotypes 1 to 5 mediated tumor cell directed gene transfer and improvement of transduction efficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic stability of self-complementary adeno-associated virus 2 during early stages of transduction in mouse muscle in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Rapid, widespread transduction of the murine myocardium using self-complementary Adeno-associated virus
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient transduction of skeletal muscle using vectors based on adeno-associated virus serotype 6.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus (AAV) vectors in the CNS.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brain
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Significantly increased lifespan and improved behavioral performances by rAAV gene delivery in adult mucopolysaccharidosis IIIB mice
1 reference
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons
1 reference
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Crossref
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7 January 2021
based on heuristic
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Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model.
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intraneural colchicine inhibition of adenoviral and adeno-associated viral vector remote spinal cord gene delivery
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Efficient retrograde neuronal transduction utilizing self-complementary AAV1
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated viral vectors and the retina
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
AAV-mediated gene therapy for retinal disorders: from mouse to man.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Versatility of AAV vectors for retinal gene transfer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of gene therapy on visual function in Leber's congenital amaurosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Safety and efficacy of gene transfer for Leber's congenital amaurosis
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Virus-mediated transduction of murine retina with adeno-associated virus: effects of viral capsid and genome size.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ocular gene transfer with self-complementary AAV vectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assessment of ocular transduction using single-stranded and self-complementary recombinant adeno-associated virus serotype 2/8.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of AAV transduction in glaucoma-associated human trabecular meshwork cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of viral vectors and virion shells in cellular gene expression
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-facilitated nuclear translocation of adeno-associated virus type 2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting gene expression to cones with human cone opsin promoters in recombinant AAV.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus type 2-mediated transduction in primary human bone marrow-derived CD34+ hematopoietic progenitor cells: donor variation and correlation of transgene expression with cellular differentiation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic stem cell transduction by recombinant adeno-associated virus vectors: problems and solutions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stable integration of recombinant adeno-associated virus vector genomes after transduction of murine hematopoietic stem cells.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant self-complementary adeno-associated virus serotype vector-mediated hematopoietic stem cell transduction and lineage-restricted, long-term transgene expression in a murine serial bone marrow transplantation model.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Integration of adeno-associated virus (AAV) and recombinant AAV vectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
AAV serotype 2 vectors preferentially integrate into active genes in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AAV loves an active genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced transduction of mouse bone marrow-derived dendritic cells by repetitive infection with self-complementary adeno-associated virus 6 combined with immunostimulatory ligands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Major subsets of human dendritic cells are efficiently transduced by self-complementary adeno-associated virus vectors 1 and 2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adeno-associated virus mediated gene transfer into lung cancer cells promoting CD40 ligand-based immunotherapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of gene transfer with recombinant adeno-associated virus (rAAV) vectors into primary B-cell chronic lymphocytic leukemia cells by CpG-oligodeoxynucleotides
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
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7 January 2021
based on heuristic
inferred from DOI database lookup
Host cell DNA repair pathways in adeno-associated viral genome processing
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of adeno-associated virus DNA hairpin structure on recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FMT.2008.171
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/MT.2008.171
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
PubMed ID
18682697
1 reference
stated in
Europe PubMed Central
PubMed ID
18682697
retrieved
4 August 2017
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