(Q34819748)

4 August 2017

title

Regulation of Drosophila lifespan by JNK signaling (English)

1 reference

4 August 2017

0 references

1 reference

4

Heinrich Jasper

1 reference

4 August 2017

Benoit Biteau

1

1 reference

4 August 2017

Jason Karpac

series ordinal

2

1 reference

4 August 2017

Daesung Hwangbo

series ordinal

3

1 reference

4 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21111799

4 September 2024

publication date

25 November 2010

1 reference

full work available at URL

4 August 2017

https://europepmc.org/articles/pmc3079798?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21111799/?tool=EBI

4 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21111799/pdf/?tool=EBI

4 September 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://europepmc.org/articles/PMC3079798

4 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://europepmc.org/articles/PMC3079798?pdf=render

4 September 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://doi.org/10.1016/j.exger.2010.11.003

4 September 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21111799

https://api.elsevier.com/content/article/PII:S0531556510003906?httpAccept=text/xml

4 September 2024

1 reference

10.1016/J.EXGER.2010.11.003

Crossref

DOI

https://api.crossref.org/works/10.1016/J.EXGER.2010.11.003

https://api.elsevier.com/content/article/PII:S0531556510003906?httpAccept=text/plain

4 September 2024

1 reference

10.1016/J.EXGER.2010.11.003

Crossref

DOI

https://api.crossref.org/works/10.1016/J.EXGER.2010.11.003

4 September 2024

published in

Experimental Gerontology

1 reference

4 August 2017

volume

46

1 reference

4 August 2017

issue

5

1 reference

4 August 2017

page(s)

349-354

1 reference

Lifespan extension by preserving proliferative homeostasis in Drosophila

4 August 2017

cites work

1 reference

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cJun NH2-terminal kinase 1 (JNK1): roles in metabolic regulation of insulin resistance

8 July 2018

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

8 July 2018

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Nonresolving inflammation

8 July 2018

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Stress-activated cap'n'collar transcription factors in aging and human disease

8 July 2018

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Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

8 July 2018

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It's all about balance: p53 and aging

8 July 2018

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The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila

8 July 2018

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A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

8 July 2018

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A non-redundant role for Drosophila Mkk4 and hemipterous/Mkk7 in TAK1-mediated activation of JNK

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

8 July 2018

1 reference

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Induction of autophagy by spermidine promotes longevity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK/FOXO-mediated neuronal expression of fly homologue of peroxiredoxin II reduces oxidative stress and extends life span

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK signaling in insulin-producing cells is required for adaptive responses to stress in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut

8 July 2018

1 reference

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JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Sir2 and longevity: the p53 connection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling

8 July 2018

1 reference

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Hormesis, aging and longevity

8 July 2018

1 reference

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Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.

8 July 2018

1 reference

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Insulin and JNK: optimizing metabolic homeostasis and lifespan

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

14-3-3 Epsilon antagonizes FoxO to control growth, apoptosis and longevity in Drosophila

8 July 2018

1 reference

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Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Two neurons mediate diet-restriction-induced longevity in C. elegans

8 July 2018

1 reference

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The c-jun kinase/stress-activated pathway: regulation, function and role in human disease

8 July 2018

1 reference

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Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation.

8 July 2018

1 reference

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Inflammation and metabolic disorders

8 July 2018

1 reference

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The response of human epithelial cells to TNF involves an inducible autocrine cascade

8 July 2018

1 reference

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Puckered, a Drosophila MAPK phosphatase, ensures cell viability by antagonizing JNK-induced apoptosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

From JNK to pay dirt: jun kinases, their biochemistry, physiology and clinical importance

8 July 2018

1 reference

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Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

8 July 2018

1 reference

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Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The plasticity of aging: insights from long-lived mutants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

JNK Signaling Confers Tolerance to Oxidative Stress and Extends Lifespan in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The endocrine regulation of aging by insulin-like signals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Activation of the JNK signaling pathway: breaking the brake on apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Sequential activation of signaling pathways during innate immune responses in Drosophila.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Involvement of c-Jun N-terminal kinase in oxidative stress-mediated suppression of insulin gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The JNK signal transduction pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The lipocalin protein family: structure and function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

An innate immune response of blood cells to tumors and tissue damage in Drosophila

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Realized immune response is enhanced in long-lived puc and chico mutants but is unaffected by dietary restriction.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The genomic response of the Drosophila embryo to JNK signaling.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Lipocalins and Insulin Resistance: Etiological Role of Retinol-Binding Protein 4 and Lipocalin-2?

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079798

The JNK signal transduction pathway

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21111799

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EXGER.2010.11.003

1 reference

4 August 2017

1 reference

4 August 2017

1 reference