(Q34857481)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

0 references

1 reference

GOA release 2020-03-11

Glucagon

1 reference

GOA release 2020-03-11

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Stephan Wueest

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Yannick D Muller

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Daniel Konrad

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Frank Reimann

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Fiona Gribble

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Jan A Ehses

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

18

Daniel J Drucker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

author name string

Helga Ellingsgaard

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Irina Hauselmann

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Beat Schuler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Laurie L Baggio

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Daniel T Meier

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Elisabeth Eppler

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Karim Bouzakri

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Ann Maria Kruse Hansen

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Manfred Reinecke

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Max Gassmann

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Philippe A Halban

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Jesper Gromada

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Marc Y Donath

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

language of work or name

English

0 references

publication date

30 October 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

page(s)

1481-1489

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nm.2513

15 January 2020

exact match

0 references

cites work

Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Successful modulation of type 2 diabetes in db/db mice with intra-bone marrow--bone marrow transplantation plus concurrent thymic transplantation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Intraislet production of GLP-1 by activation of prohormone convertase 1/3 in pancreatic α-cells in mouse models of ß-cell regeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Unique arrangement of alpha- and beta-cells in human islets of Langerhans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Human IL6 enhances leptin action in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Glucose sensing in L cells: a primary cell study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Muscle as an endocrine organ: focus on muscle-derived interleukin-6.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Interleukin-6 regulates pancreatic alpha-cell mass expansion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Direct cross-talk of interleukin-6 and insulin signal transduction via insulin receptor substrate-1 in skeletal muscle cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Plasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Indinavir uncovers different contributions of GLUT4 and GLUT1 towards glucose uptake in muscle and fat cells and tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Glucose ingestion attenuates interleukin-6 release from contracting skeletal muscle in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Role of leptin in the regulation of glucagon-like peptide-1 secretion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

8 July 2018

1 reference

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Regulation of pancreatic PC1 and PC2 associated with increased glucagon-like peptide 1 in diabetic rats

8 July 2018

1 reference

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The glucagon-like peptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

The incretin concept today

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4).

8 July 2018

1 reference

How obesity causes diabetes: not a tall tale

21 January 2018

1 reference

Hamster preproglucagon contains the sequence of glucagon and two related peptides.

21 January 2018

1 reference

Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice

21 January 2018

1 reference

Ontogeny of regeneration of beta-cells in the neonatal rat after treatment with streptozotocin.

21 January 2018

1 reference

Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy

21 January 2018

1 reference

Increased number of islet-associated macrophages in type 2 diabetes.

21 January 2018

1 reference

Changes in gut hormone levels and negative energy balance during aerobic exercise in obese young males.

21 January 2018

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Activity-induced GLP-1 release in lean and obese subjects

21 January 2018

1 reference

Effects of exercise on gut peptides, energy intake and appetite.

21 January 2018

1 reference

GLP-1 and appetite responses to a meal in lean and overweight adolescents following exercise.

21 January 2018

1 reference

Physical training may enhance beta-cell function in type 2 diabetes.

21 January 2018

1 reference

Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness

21 January 2018

1 reference

Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity

21 January 2018

1 reference

Prolonged interleukin-6 administration enhances glucose tolerance and increases skeletal muscle PPARalpha and UCP2 expression in rats

21 January 2018

1 reference

Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice.

21 January 2018

1 reference

Interleukin-6-deficient mice develop mature-onset obesity

21 January 2018

1 reference

Effects of insulin--like growth factor-I treatment on the endocrine pancreas of hypophysectomized rats: comparison with growth hormone replacement.

21 January 2018

1 reference

The effect of hypophysectomy on pancreatic islet hormone and insulin-like growth factor I content and mRNA expression in rat.

21 January 2018

1 reference

Proliferation of sorted human and rat beta cells

21 January 2018

1 reference

Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus—an adaptive response to hyperglycaemia?

21 January 2018

1 reference

Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running

21 January 2018

1 reference

Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

21 January 2018

1 reference

Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4286294

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV

9 December 2018

1 reference

12 December 2020

Counterpoint: Interleukin-6 does not have a beneficial role in insulin sensitivity and glucose homeostasis

1 reference

12 December 2020

Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

1 reference

12 December 2020

Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

1 reference

12 December 2020

Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice

1 reference

12 December 2020

Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.2513

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22037645%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference