(Q34871321)

5 August 2017

Gut homeostasis in a microbial world: insights from Drosophila melanogaster (English)

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5 August 2017

Drosophila melanogaster

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author

Bruno Lemaitre

series ordinal

3

1 reference

5 August 2017

Nicolas Buchon

1

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Nichole A. Broderick

object named as

Nichole A Broderick

series ordinal

2

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language of work or name

English

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publication date

29 July 2013

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Nature Reviews Microbiology

5 August 2017

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5 August 2017

11

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5 August 2017

9

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5 August 2017

615-626

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https://scigraph.springernature.com/pub.10.1038/nrmicro3074

5 August 2017

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cites work

The host defense of Drosophila melanogaster

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https://api.crossref.org/works/10.1038%2FNRMICRO3074

The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience

21 January 2018

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Gut-microbiota interactions in non-mammals: what can we learn from Drosophila?

21 January 2018

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Drosophila melanogaster as a model for human intestinal infection and pathology

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Food of Drosophila Melanogaster Meigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A COMPARISON OF DROSOPHILA HABITATS ACCORDING TO THE PHYSIOLOGICAL ATTRIBUTES OF THE ASSOCIATED YEAST COMMUNITIES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Coadaptation ofDrosophila and yeasts in their natural habitat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Animals in a bacterial world, a new imperative for the life sciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila host defense after oral infection by an entomopathogenic Pseudomonas species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A model of bacterial intestinal infections in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Morphological and molecular characterization of adult midgut compartmentalization in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Innate immune homeostasis by the homeobox gene caudal and commensal-gut mutualism in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Increased internal and external bacterial load during Drosophila aging without life-span trade-off

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Geographical distribution and diversity of bacteria associated with natural populations of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Gut-associated microbes of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The persistence of a microbial flora during postembryogenesis of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Commensal bacteria play a role in mating preference of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila regulate yeast density and increase yeast community similarity in a natural substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Clash of kingdoms or why Drosophila larvae positively respond to fungal competitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Impact of the resident microbiota on the nutritional phenotype of Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Tissue damage-induced intestinal stem cell division in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Altered modes of stem cell division drive adaptive intestinal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Peritrophic matrix structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

New insights into peritrophic matrix synthesis, architecture, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Always one step ahead: How pathogenic bacteria use the type III secretion system to manipulate the intestinal mucosal immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A potential role for Drosophila mucins in development and physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

big bang gene modulates gut immune tolerance in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Tissue-specific inducible expression of antimicrobial peptide genes in Drosophila surface epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Drosophila immune system detects bacteria through specific peptidoglycan recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Drosophila amidase PGRP-LB modulates the immune response to bacterial infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Bacterial cell-wall recycling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Pirk is a negative regulator of the Drosophila Imd pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Rudra interrupts receptor signaling complexes to negatively regulate the IMD pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Drosophila peptidoglycan recognition protein PGRP-LF blocks PGRP-LC and IMD/JNK pathway activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Negative regulation of immune responses on the fly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Positive and negative regulation of the Drosophila immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A direct role for dual oxidase in Drosophila gut immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Dual oxidase in mucosal immunity and host-microbe homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Essential role of Duox in stabilization of Drosophila wing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Duox, Flotillin-2, and Src42A are required to activate or delimit the spread of the transcriptional response to epidermal wounds in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Determination of the disulfide array of the first inducible antifungal peptide from insects: drosomycin from Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Drosomycin, an essential component of antifungal defence in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Drosophila larva as a tool to study gut-associated macrophages: PI3K regulates a discrete hemocyte population at the proventriculus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Pathogenic stimulation of intestinal stem cell response in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Synergy between bacterial infection and genetic predisposition in intestinal dysplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

EGF signaling regulates the proliferation of intestinal stem cells in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Intestinal barrier dysfunction links metabolic and inflammatory markers of aging to death in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Taxonomic characterisation of Pseudomonas strain L48 and formal proposal of Pseudomonas entomophila sp. nov.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Bacterial pore-forming toxins: the (w)hole story?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Pore-forming toxins induce multiple cellular responses promoting survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Monalysin, a novel ß-pore-forming toxin from the Drosophila pathogen Pseudomonas entomophila, contributes to host intestinal damage and lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Recognition of pathogenic microbes by the Drosophila phagocytic pattern recognition receptor Eater

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Pseudomonas aeruginosa RhlR is required to neutralize the cellular immune response in a Drosophila melanogaster oral infection model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Spatially selective colonization of the arthropod intestine through activation of Vibrio cholerae biofilm formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Bacterial strategies to overcome insect defences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Insecticidal activity of Bacillus thuringiensis crystal proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Intestinal antimicrobial peptides during homeostasis, infection, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Salmonella regulation of intestinal stem cells through the Wnt/beta-catenin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Evidence that stem cells reside in the adult Drosophila midgut epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

The adult Drosophila posterior midgut is maintained by pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Genes that fight infection: what the Drosophila genome says about animal immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

Effects of microbial floras on the distributions of five domestic Drosophila species across fruit resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO3074

31 March 2020

Identifiers

DOI

10.1038/NRMICRO3074

1 reference

PubMed ID

23893105

Dimensions Publication ID

5 August 2017

0 references

1 reference

PubMed ID

23893105