(Q34872888)

English

Variation in genes encoding the neuroactive steroid synthetic enzymes 5α-reductase type 1 and 3α-reductase type 2 is associated with alcohol dependence

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Variation in genes encoding the neuroactive steroid synthetic enzymes 5α-reductase type 1 and 3α-reductase type 2 is associated with alcohol dependence (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

object named as

Joel Gelernter

3

0 references

Jonathan Covault

5

object named as

Jonathan Covault

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Henry R. Kranzler

2

object named as

Henry R Kranzler

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Verica Milivojevic

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Linda Burian

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

15 February 2011

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Alcoholism: Clinical and Experimental Research

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

946-952

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Human variation in alcohol response is influenced by variation in neuronal signaling genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

The effect of allelic variation in aldo-keto reductase 1C2 on the in vitro metabolism of dihydrotestosterone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Mass spectrometric assay and physiological-pharmacological activity of androgenic neurosteroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Neurosteroids: endogenous regulators of the GABA(A) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3alpha-androstanediol and 17beta-estradiol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

A role for GABA mechanisms in the motivational effects of alcohol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Neurosteroids: biochemistry and clinical significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Antinociceptive properties of neurosteroids III: experiments with alphadolone given intravenously, intraperitoneally, and intragastrically

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

A guide to 17beta-hydroxysteroid dehydrogenases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Anticonvulsant profile of the progesterone metabolite 5 alpha-pregnan-3 alpha-ol-20-one

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Anxiolytic activity of the progesterone metabolite 5α-pregnan-3α-ol-20-one

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

Neuroactive steroids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

8 July 2018

The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Neurosteroids mediate pharmacological effects of ethanol: a new mechanism of ethanol action?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

The effect of a low dose of alcohol on allopregnanolone serum concentrations across the menstrual cycle in women with severe premenstrual syndrome and controls

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Subjective effects and changes in steroid hormone concentrations in humans following acute consumption of alcohol

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

Alcohol intoxication increases allopregnanolone levels in male adolescent humans

1 reference

https://api.crossref.org/works/10.1111%2FJ.1530-0277.2010.01425.X

21 January 2018

The ability of the Self-Rating of the Effects of Alcohol (SRE) Scale to predict alcohol-related outcomes five years later.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

26 October 2018

Alcohol Intoxication Increases Allopregnanolone Levels in Female Adolescent Humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

26 October 2018

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083475

26 October 2018

The role of GABAergic neuroactive steroids in ethanol action, tolerance and dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/21323680

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral effects of 3 alpha-androstanediol. I: Modulation of sexual receptivity and promotion of GABA-stimulated chloride flux

1 reference

https://pubmed.ncbi.nlm.nih.gov/21323680

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1530-0277.2010.01425.X

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

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