(Q36297266)

13 August 2017

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title

Relevance of endogenous 3alpha-reduced neurosteroids to depression and antidepressant action (English)

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13 August 2017

Veska Uzunova

1

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PubMed ID

16249906

13 August 2017

Luther Sampson

series ordinal

2

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PubMed ID

16249906

13 August 2017

Doncho P Uzunov

series ordinal

3

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13 August 2017

26 October 2005

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13 August 2017

11

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inferred from page(s)

published in

Psychopharmacology

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13 August 2017

186

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13 August 2017

3

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13 August 2017

351-361

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https://scigraph.springernature.com/pub.10.1007/s00213-005-0201-6

13 August 2017

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Effects of antidepressant treatment on neuroactive steroids in major depression

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The amygdala mediates the anxiolytic-like effect of the neurosteroid allopregnanolone in rat.

21 January 2018

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12 December 2020

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

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12 December 2020

Profiling neurosteroids in cerebrospinal fluids and plasma by gas chromatography/electron capture negative chemical ionization mass spectrometry

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12 December 2020

Neurosteroids and GABAA receptor function.

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12 December 2020

Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor.

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12 December 2020

Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected?

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12 December 2020

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

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12 December 2020

In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine

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12 December 2020

Progesterone reduces immobility in rats forced to swim

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12 December 2020

Pharmacology of endogenous neuroactive steroids.

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12 December 2020

Neuropsychopharmacological properties of neuroactive steroids

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12 December 2020

Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim

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12 December 2020

Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

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12 December 2020

The specificity of stress responses to different nocuous stimuli: neurosteroids and depression

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12 December 2020

Neurosteroids in depression: a review

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12 December 2020

Simultaneous radioimmunoassay of progesterone, androst-4-enedione, pregnenolone, dehydroepiandrosterone and 17-hydroxyprogesterone in specific regions of human brain.

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12 December 2020

Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

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12 December 2020

Neuroactive steroids in responders and nonresponders to sleep deprivation

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12 December 2020

Brain output dysregulation induced by olfactory bulbectomy: an approximation in the rat of major depressive disorder in humans?

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12 December 2020

Olfactory bulbectomy as a model for agitated hyposerotonergic depression

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12 December 2020

From monoamines to genomic targets: a paradigm shift for drug discovery in depression

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12 December 2020

Serotonergic agents modulate antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice.

1 reference

12 December 2020

Concentrations of 3 alpha-reduced neuroactive steroids and their precursors in plasma of patients with major depression and after clinical recovery.

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12 December 2020

Current perspectives on the role of neurosteroids in PMS and depression

1 reference

12 December 2020

Neurosteroids: biochemistry and clinical significance

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12 December 2020

Progesterone, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-5alpha-pregnane-20-one in specific regions of the human female brain in different endocrine states.

1 reference

12 December 2020

The role of neurosteroids in the anxiolytic,antidepressive- and anticonvulsive effects of selective serotonin reuptake inhibitors

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12 December 2020

The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

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12 December 2020

Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

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12 December 2020

Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression

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12 December 2020

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12 December 2020

Region-specific dysregulation of allopregnanolone brain content in the olfactory bulbectomized rat model of depression

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12 December 2020

Neurosteroid metabolism in the human brain

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12 December 2020

Plasma concentrations of neuroactive steroids before and after electroconvulsive therapy in major depression

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12 December 2020

Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders

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12 December 2020

Hippocampal 3alpha,5alpha-THP may alter depressive behavior of pregnant and lactating rats

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12 December 2020

Potential clinical uses of neuroactive steroids

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12 December 2020

Antidepressant-like effect of the neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one in mice forced swim test.

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12 December 2020

Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology

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12 December 2020

Neuroactive steroids: mechanisms of action and neuropsychopharmacological perspectives

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12 December 2020

Antidepressant-like actions of intra-accumbens infusions of allopregnanolone in ovariectomized Wistar rats

1 reference

12 December 2020

Reduced olfactory performance in patients with major depression.

1 reference

12 December 2020

Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim

1 reference

12 December 2020

Plasma concentrations of neuroactive steroids before and after repetitive transcranial magnetic stimulation (rTMS) in major depression

1 reference

12 December 2020

Circulating levels of allopregnanolone in humans: gender, age, and endocrine influences.

1 reference

12 December 2020

Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol

1 reference

12 December 2020

Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids

1 reference

12 December 2020

Chronic antidepressants reverse cerebrocortical allopregnanolone decline in the olfactory-bulbectomized rat.

1 reference

12 December 2020

Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments

1 reference

12 December 2020

Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy

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12 December 2020

Neurosteroids and neuroactive drugs in mental disorders

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12 December 2020

Selective serotonin reuptake inhibitors in affective disorders--II. Efficacy and quality of life

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12 December 2020

Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test

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12 December 2020

Changes in progesterone metabolites in the hippocampus can modulate open field and forced swim test behavior of proestrous rats

1 reference

12 December 2020

Assessing antidepressant activity in rodents: recent developments and future needs

1 reference

12 December 2020

Neurobiology of depression

1 reference

12 December 2020

Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase

1 reference

12 December 2020

Fluoxetine-elicited changes in brain neurosteroid content measured by negative ion mass fragmentography

1 reference

12 December 2020

Emotion circuits in the brain

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12 December 2020

Influence of sleep deprivation on neuroactive steroids in major depression

1 reference

12 December 2020

Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).

1 reference

12 December 2020

Forced swimming test in mice: a review of antidepressant activity

1 reference

12 December 2020

Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat.

1 reference

12 December 2020

Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain.

1 reference

12 December 2020

Is there a physiological role for the neurosteroid THDOC in stress-sensitive conditions?

1 reference

12 December 2020

Permissive role of brain allopregnanolone content in the regulation of pentobarbital-induced righting reflex loss.

1 reference

12 December 2020

GABA and glutamate systems as therapeutic targets in depression and mood disorders

1 reference

12 December 2020

Neurosteroids: beginning of the story

1 reference

12 December 2020

Can the antidysphoric and anxiolytic profiles of selective serotonin reuptake inhibitors be related to their ability to increase brain 3 alpha, 5 alpha-tetrahydroprogesterone (allopregnanolone) availability?

1 reference

12 December 2020

Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones

1 reference

12 December 2020

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

1 reference

12 December 2020

Neuroimaging studies of mood disorders

1 reference

12 December 2020

The regional brain distribution of the neurosteroids pregnenolone and pregnenolone sulfate following intravenous infusion.

1 reference

12 December 2020

Neurosteroids: a novel function of the brain.

1 reference

12 December 2020

Research and treatment approaches to depression

1 reference

12 December 2020

Neuroactive steroid concentrations following metyrapone administration in depressed patients and healthy volunteers.

1 reference

12 December 2020

Steroids, neuroactive steroids and neurosteroids in psychopathology

1 reference

12 December 2020

Radioimmunoassay of 3 alpha-hydroxy-5 alpha-pregnan-20-one in rat and human plasma.

1 reference

12 December 2020

The clinical potentials of endogenous neurosteroids.

1 reference

12 December 2020

The forced swimming test as a model for core and component behavioral effects of antidepressant drugs.

1 reference

12 December 2020

Neurosteroid modulation of GABAA receptors

1 reference

12 December 2020

Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain

1 reference

12 December 2020

Antidepressants selectively antagonize the hyperactivity induced in rats by long-term isolation

1 reference

12 December 2020

In Vivo Uptake of [3H]Progesterone and [3H]-5α-Dihydroprogesterone by Rat Brain and Pituitary and Effects of Estradiol and Time: Tissue Concentration of Progesterone Itself or Specific Metabolites?*

1 reference

12 December 2020

Fluoxetine decreases concentrations of 3 alpha, 5 alpha-tetrahydrodeoxycorticosterone (THDOC) in major depression.

1 reference

12 December 2020

The olfactory bulbectomized rat as a model of depression: an update

1 reference

12 December 2020

10.1007/S00213-005-0201-6

Identifiers

DOI

1 reference

13 August 2017

1 reference

PubMed ID

16249906