(Q34878458)

5 August 2017

1 reference

title

Role of post-translational modifications of HTLV-1 Tax in NF-κB activation (English)

1 reference

Human T-lymphotropic virus 1

5 August 2017

main subject

0 references

NF-κB

0 references

author name string

Noula Shembade

series ordinal

1

1 reference

5 August 2017

Edward W. Harhaj

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21540989

1 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21540989

1 December 2024

publication date

1 January 2010

1 reference

5 August 2017

26 January 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21540989

full work available at URL

1 December 2024

https://doi.org/10.4331/wjbc.v1.i1.13

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21540989

https://europepmc.org/articles/PMC3083931

1 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21540989

https://europepmc.org/articles/PMC3083931?pdf=render

1 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21540989

World journal of biological chemistry

1 December 2024

published in

1 reference

5 August 2017

volume

1

1 reference

5 August 2017

issue

1

1 reference

5 August 2017

page(s)

13-20

1 reference

The HTLV-1 Tax protein: revealing mechanisms of transcriptional activation through histone acetylation and nucleosome disassembly

5 August 2017

cites work

1 reference

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NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein

8 July 2018

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Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway

8 July 2018

1 reference

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The ubiquitin-editing enzyme A20 requires RNF11 to downregulate NF-kappaB signalling

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Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

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Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-kappaB activation

8 July 2018

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HTLV-1 Tax-mediated TAK1 activation involves TAB2 adapter protein

8 July 2018

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The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation

8 July 2018

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Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome

8 July 2018

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Implication of the HTLV-I bZIP factor gene in the leukemogenesis of adult T-cell leukemia

8 July 2018

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Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line

8 July 2018

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Essential role for TAX1BP1 in the termination of TNF-alpha-, IL-1- and LPS-mediated NF-kappaB and JNK signaling

8 July 2018

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Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK

8 July 2018

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Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription.

8 July 2018

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Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase

8 July 2018

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Human T cell leukemia virus type I is resistant to the antiviral effects of APOBEC3.

8 July 2018

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Coactivator-associated arginine methyltransferase 1 enhances transcriptional activity of the human T-cell lymphotropic virus type 1 long terminal repeat through direct interaction with Tax.

8 July 2018

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Human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 use different receptor complexes to enter T cells

8 July 2018

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Genotoxic stress and cellular stress alter the subcellular distribution of human T-cell leukemia virus type 1 tax through a CRM1-dependent mechanism

8 July 2018

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DC-SIGN facilitates fusion of dendritic cells with human T-cell leukemia virus type 1-infected cells

8 July 2018

1 reference

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HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated

8 July 2018

1 reference

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A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization

8 July 2018

1 reference

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Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation

8 July 2018

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HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells

8 July 2018

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Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein

8 July 2018

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Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues

8 July 2018

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Impact of HTLV-I Tax on cell cycle progression and the cellular DNA damage repair response

8 July 2018

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Molecular mechanisms of cellular transformation by HTLV-1 Tax.

8 July 2018

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Activation of NF-kappaB by HTLV-I and implications for cell transformation

8 July 2018

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Ubiquitin signalling in the NF-kappaB pathway

8 July 2018

1 reference

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Mechanisms of persistent NF-kappaB activation by HTLV-I tax.

8 July 2018

1 reference

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Human T lymphotropic virus type-1 p30II alters cellular gene expression to selectively enhance signaling pathways that activate T lymphocytes

8 July 2018

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Stable ubiquitination of human T-cell leukemia virus type 1 tax is required for proteasome binding

8 July 2018

1 reference

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Ubiquitination of human T-cell leukemia virus type 1 tax modulates its activity.

8 July 2018

1 reference

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Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.

8 July 2018

1 reference

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Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

8 July 2018

1 reference

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A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution

8 July 2018

1 reference

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De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

8 July 2018

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Suppression of tumor growth and cell proliferation by p13II, a mitochondrial protein of human T cell leukemia virus type 1

8 July 2018

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The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV

8 July 2018

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Protein profile of tax-associated complexes

8 July 2018

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Human T-cell leukemia virus type 1 envelope glycoprotein gp46 interacts with cell surface heparan sulfate proteoglycans

8 July 2018

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Cellular transformation by the HTLV-I Tax protein, a jack-of-all-trades

8 July 2018

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Human T-cell leukemia virus type I and adult T-cell leukemia

8 July 2018

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The current status of therapy for adult T-cell leukaemia-lymphoma in Japan

8 July 2018

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Human T cell leukemia virus type I-induced disease: pathways to cancer and neurodegeneration

8 July 2018

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Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.

8 July 2018

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A conserved calcineurin-binding motif in human T lymphotropic virus type 1 p12I functions to modulate nuclear factor of activated T cell activation

8 July 2018

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Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

8 July 2018

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The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription

8 July 2018

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Physical interaction of human T-cell leukemia virus type 1 Tax with cyclin-dependent kinase 4 stimulates the phosphorylation of retinoblastoma protein

8 July 2018

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Human T cell leukemia virus type I and neurologic disease: events in bone marrow, peripheral blood, and central nervous system during normal immune surveillance and neuroinflammation

8 July 2018

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Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha

8 July 2018

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Mechanisms of Tax Regulation of Human T Cell Leukemia Virus Type I Gene Expression

8 July 2018

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CD8(+) T cells are an in vivo reservoir for human T-cell lymphotropic virus type I.

8 July 2018

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

8 July 2018

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Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

8 July 2018

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NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

8 July 2018

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8 July 2018

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Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

8 July 2018

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Domain-specific interaction with the I kappa B kinase (IKK)regulatory subunit IKK gamma is an essential step in tax-mediated activation of IKK.

8 July 2018

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The immune response to HTLV-I.

8 July 2018

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Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein

8 July 2018

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Human T cell lymphotropic virus type I genomic expression and impact on intracellular signaling pathways during neurodegenerative disease and leukemia

8 July 2018

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Global epidemic of human T-cell lymphotropic virus type-I (HTLV-I).

8 July 2018

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Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

8 July 2018

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Phosphorylation of the human T-cell leukemia virus type 1 transactivator tax on adjacent serine residues is critical for tax activation

8 July 2018

1 reference

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CREB-2, a cellular CRE-dependent transcription repressor, functions in association with Tax as an activator of the human T-cell leukemia virus type 1 promoter

8 July 2018

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Human T-cell leukemia virus type 1 Tax and cell cycle progression: role of cyclin D-cdk and p110Rb

8 July 2018

1 reference

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A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha

8 July 2018

1 reference

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Anchoring of CREB Binding Protein to the Human T-Cell Leukemia Virus Type 1 Promoter: a Molecular Mechanism of Tax Transactivation

8 July 2018

1 reference

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Differential expression of alternatively spliced pX mRNAs in HTLV-I-infected cell lines

8 July 2018

1 reference

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Transgenic mouse models for HTLV-I infection

8 July 2018

1 reference

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HTLV-1 Tax protein interacts with cyclin-dependent kinase inhibitor p16INK4A and counteracts its inhibitory activity towards CDK4.

8 July 2018

1 reference

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Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

8 July 2018

1 reference

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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease

8 July 2018

1 reference

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Induction of interleukin 2 receptor gene expression by p40x encoded by human T-cell leukemia virus type 1.

8 July 2018

1 reference

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Blood transfusion and HTLV-I associated myelopathy.

8 July 2018

1 reference

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HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene

8 July 2018

1 reference

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Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector

8 July 2018

1 reference

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Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

HTLV-1 Tax is a critical lipid raft modulator that hijacks IkappaB kinases to the microdomains for persistent activation of NF-kappaB.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Site-specific phosphorylation differentiates active from inactive forms of the human T-cell leukemia virus type 1 Tax oncoprotein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Preferential selection of human T-cell leukemia virus type I provirus integration sites in leukemic versus carrier states

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Engagement of specific T-cell surface molecules regulates cytoskeletal polarization in HTLV-1-infected lymphocytes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Influence of cytokine and mannose binding protein gene polymorphisms on human T-cell leukemia virus type I (hTLV-I) provirus load in HTLV-I asymptomatic carriers

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Ablation of transplanted HTLV-I tax-transformed tumors in mice by antisense inhibition of NF-kappa B.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083931

Combined intraarterial cisplatin infusion and radiation therapy for invasive bladder cancer

26 October 2018

series ordinal

36

1 reference

Crossref

DOI

10.4331/WJBC.V1.I1.13

https://api.crossref.org/works/10.4331/WJBC.V1.I1.13

1 December 2024

Identifiers

DOI

10.4331/WJBC.V1.I1.13

1 reference

5 August 2017

1 reference

5 August 2017

1 reference