(Q34898560)

5 August 2017

title

Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma (English)

1 reference

5 August 2017

Jason Roszik

4

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Alexander J. Lazar

object named as

Alexander J Lazar

36

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Funda Meric-Bernstam

33

object named as

Funda Meric-Bernstam

1 reference

5 August 2017

24

Patrick Hwu

1 reference

5 August 2017

37

Michael A Davies

1 reference

5 August 2017

8

Victor G Prieto

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5 August 2017

9

Michael Tetzlaff

1 reference

5 August 2017

Jeffrey E Gershenwald

18

object named as

Jeffrey E Gershenwald

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5 August 2017

19

Rodabe N Amaria

1 reference

5 August 2017

31

Gordon B Mills

1 reference

5 August 2017

26

Scott E Woodman

1 reference

5 August 2017

7

Lauren Haydu

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1

Alan E Siroy

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5 August 2017

11

Wei-Lien Wang

1 reference

5 August 2017

12

Carlos Torres-Cabala

1 reference

5 August 2017

23

Wen-Jen Hwu

1 reference

5 August 2017

25

Adi Diab

1 reference

5 August 2017

35

Mark J Routbort

1 reference

5 August 2017

30

Kenna R Shaw

1 reference

5 August 2017

Genevieve M Boland

2

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5 August 2017

Denái R Milton

3

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5 August 2017

Silva Frankian

5

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5 August 2017

Jared Malke

6

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5 August 2017

Doina Ivan

10

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5 August 2017

Jonathan Curry

13

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5 August 2017

Sinchita Roy-Chowdhuri

14

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5 August 2017

Russell Broaddus

15

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5 August 2017

Asif Rashid

16

1 reference

5 August 2017

John Stewart

17

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5 August 2017

Sapna P Patel

20

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5 August 2017

Nicholas E Papadopoulos

21

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5 August 2017

Agop Bedikian

22

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5 August 2017

Kenneth D Aldape

27

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5 August 2017

Rajyalakshmi Luthra

28

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5 August 2017

Keyur P Patel

29

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5 August 2017

John Mendelsohn

32

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5 August 2017

Kevin B Kim

34

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5 August 2017

language of work or name

English

0 references

publication date

22 August 2014

1 reference

5 August 2017

number of pages

8

1 reference

Journal of Investigative Dermatology

inferred from page(s)

published in

1 reference

5 August 2017

volume

135

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5 August 2017

issue

2

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5 August 2017

page(s)

508-515

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describes a project that uses

5 August 2017

massive parallel sequencing

1 reference

https://scigraph.springernature.com/pub.10.1038/jid.2014.366

inferred from title

exact match

0 references

cites work

Cancer statistics, 2014

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

BRAF fusions define a distinct molecular subset of melanomas with potential sensitivity to MEK inhibition

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Imatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

A landscape of driver mutations in melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Melanoma genome sequencing reveals frequent PREX2 mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

New strategies in melanoma: molecular testing in advanced disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

NRAS mutation status is an independent prognostic factor in metastatic melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

KIT as a therapeutic target in metastatic melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

BRAF mutations in cutaneous melanoma are independently associated with age, anatomic site of the primary tumor, and the degree of solar elastosis at the primary tumor site

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Somatic activation of KIT in distinct subtypes of melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Distinct sets of genetic alterations in melanoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Mutations of the BRAF gene in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Metastatic melanoma of unknown primary resembles the genotype of cutaneous melanomas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Mutations in KIT occur at low frequency in melanomas arising from anatomical sites associated with chronic and intermittent sun exposure

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

Distinguishing Clinicopathologic Features of Patients with V600E and V600K BRAF-Mutant Metastatic Melanoma

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289407

p53 gene status as a predictor of tumor response to induction chemotherapy of patients with locoregionally advanced squamous cell carcinomas of the head and neck

9 December 2018

1 reference

12 December 2020

Lack of allelic deletion and point mutation as mechanisms of p53 activation in human malignant melanoma

1 reference

12 December 2020

Absence of p53 gene mutations in cutaneous melanoma

1 reference

12 December 2020

Mutation and expression of the p53 gene in human malignant melanoma

1 reference

12 December 2020

Identifiers

DOI

10.1038/JID.2014.366

1 reference

Dimensions Publication ID

5 August 2017

0 references

1 reference

5 August 2017

1 reference