(Q34907662)

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The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

The innate immunity adaptor SARM translocates to the nucleus to stabilize lamins and prevent DNA fragmentation in response to pro-apoptotic signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

apoptotic process

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Jacek J. Hawiger

2

object named as

Jacek Hawiger

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Chad R Sethman

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

language of work or name

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publication date

29 July 2013

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Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

e70994

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

29 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

SARM is required for neuronal injury and cytokine production in response to central nervous system viral infection

1 reference

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8 July 2018

Activation of the innate signaling molecule MAVS by bunyavirus infection upregulates the adaptor protein SARM1, leading to neuronal death

1 reference

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8 July 2018

Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors

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8 July 2018

T-cell death following immune activation is mediated by mitochondria-localized SARM.

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8 July 2018

Serine 162, an essential residue for the mitochondrial localization, stability and anti-apoptotic function of Mcl-1.

1 reference

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8 July 2018

Chronic inflammation and aging: DNA damage tips the balance

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ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells

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Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence

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8 July 2018

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Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs

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SARM inhibits both TRIF- and MyD88-mediated AP-1 activation.

1 reference

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Role of A-type lamins in signaling, transcription, and chromatin organization.

1 reference

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The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

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Death receptor signal transducers: nodes of coordination in immune signaling networks

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Exploring the effects of a dysfunctional nuclear matrix

1 reference

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8 July 2018

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

1 reference

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Toll-like receptors' two-edged sword: when immunity meets apoptosis.

1 reference

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Role of caspases in cleavage of lamin A/C and PARP during apoptosis in macrophages infected with a periodontopathic bacterium

1 reference

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8 July 2018

MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

1 reference

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8 July 2018

Transcription under the control of nuclear Arm/beta-catenin.

1 reference

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8 July 2018

Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop

1 reference

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Interactive sites in the MyD88 Toll/interleukin (IL) 1 receptor domain responsible for coupling to the IL1beta signaling pathway

1 reference

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The nuclear lamina comes of age.

1 reference

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8 July 2018

Importin α: a multipurpose nuclear-transport receptor

1 reference

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Requirement for a conserved Toll/interleukin-1 resistance domain protein in the Caenorhabditis elegans immune response

1 reference

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Cell death: critical control points

1 reference

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Armadillo repeat proteins: beyond the animal kingdom

1 reference

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8 July 2018

Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

1 reference

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Dynamics of the nuclear envelope at mitosis and during apoptosis

1 reference

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Nuclear apoptotic changes: an overview

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DNases and apoptosis

1 reference

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DNA topoisomerase IIalpha interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution

1 reference

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Dynamics of the nuclear lamina as monitored by GFP-tagged A-type lamins.

1 reference

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Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2

1 reference

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8 July 2018

Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells.

1 reference

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Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.

1 reference

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21 January 2018

A novel human gene (SARM) at chromosome 17q11 encodes a protein with a SAM motif and structural similarity to Armadillo/beta-catenin that is conserved in mouse, Drosophila, and Caenorhabditis elegans.

1 reference

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21 January 2018

The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.

1 reference

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21 January 2018

SARM: a novel Toll-like receptor adaptor, is functionally conserved from arthropod to human

1 reference

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Evaluation of epitope tags for protein detection after in vivo CNS gene transfer.

1 reference

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Transient expression of epitope-tagged proteins in mammalian cells.

1 reference

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TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.

1 reference

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21 January 2018

Caspase-6 latent state stability relies on helical propensity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0070994

21 January 2018

Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50.

1 reference

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26 October 2018

Identifiers

10.1371/JOURNAL.PONE.0070994

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

2013PLoSO...870994S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

ResearchGate publication ID

0 references

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