(Q34914661)

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Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Europe PubMed Central

Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). (English)

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Europe PubMed Central

PubMed publication ID

5 August 2017

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Elizabeth G Snyderwine

1

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Europe PubMed Central

PubMed publication ID

5 August 2017

Meena Venugopal

2

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Europe PubMed Central

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5 August 2017

Minshu Yu

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

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publication date

1 September 2002

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Europe PubMed Central

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5 August 2017

Mutation Research

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Europe PubMed Central

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5 August 2017

506-507

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Europe PubMed Central

PubMed publication ID

5 August 2017

145-152

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Europe PubMed Central

PubMed publication ID

5 August 2017

Mutagens, carcinogens, and tumor promoters in our daily food.

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Analysis of cooked muscle meats for heterocyclic aromatic amine carcinogens

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Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research

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A new approach to risk estimation of food-borne carcinogens--heterocyclic amines--based on molecular information

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2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, a carcinogen in high-temperature-cooked meat, and breast cancer risk

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Induction of tumors in the Zymbal gland, oral cavity, colon, skin and mammary gland of F344 rats by a mutagenic compound, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline

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A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

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Induction of mammary tumors in female Sprague-Dawley rats by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and effect of dietary fat

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Mammary gland carcinogenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Sprague-Dawley rats on high- and low-fat diets.

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Formation of DNA adducts of the food-derived mutagen 2-amino-9H-pyrido-[2,3-b]indole (A(α)C) and bioassay of mammary gland carcinogenicity in Sprague–Dawley rats

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DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis

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Selective mutagenic activation by cytochrome P3-450 of carcinogenic arylamines found in foods

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Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes

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Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

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Mutagenicity and in vitro covalent DNA binding of 2-hydroxyamino-3-methylimidazolo[4,5-f]quinoline

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Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats

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Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.

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7 January 2021

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.

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7 January 2021

Effect of CYP1A2 deficiency on heterocyclic amine DNA adduct levels in mice

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Synthesis and spectroscopic characterization of site-specific 2-amino-1-methyl-6-phenylimidazo

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7 January 2021

Mutation and repair induced by the carcinogen 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in the dihydrofolate reductase gene of Chinese hamster ovary cells and conformational modeling of the dG-C8-PhIP adduct in DNA.

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7 January 2021

Preferential induction of guanine deletion at 5'-GGGA-3' in rat mammary glands by 2-amino- 1-methyl-6-phenylimidazo[4,5-b]pyridine

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7 January 2021

Mutagenicity of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the mammary gland of Big Blue rats on high-and low-fat diets

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Proliferation, development and DNA adduct levels in the mammary gland of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a high fat diet.

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2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) retards mammary gland involution in lactating Sprague-Dawley rats.

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Investigation of mouse mammary ductal growth regulation using slow-release plastic implants

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Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine

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7 January 2021

Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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Effect of dietary fat on codon 12 and 13 Ha-ras gene mutations in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary gland tumors

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Frequent c-Ha-ras gene mutations in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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Genomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine

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Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

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Comparative genomic hybridization analysis of PhIP-induced mammary carcinomas in rats reveals a cytogenetic signature

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7 January 2021

Identifiers

10.1016/S0027-5107(02)00161-6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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