(Q34918292)

5 August 2017

title

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs (English)

1 reference

5 August 2017

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Carolina Tarantino

6

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Antonio del Sol

Antonio Del Sol

26

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Nuria Montserrat

Nuria Montserrat

5

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Enrico Cappelli

Enrico Cappelli

30

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Jordi Surrallés

Jordi Surralles

29

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Juan Bueren

Juan Bueren

Juan Carlos Izpisúa Belmonte

27

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33

Juan Carlos Izpisua Belmonte

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5 August 2017

24

Ruotong Ren

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5 August 2017

16

Yuji Tsunekawa

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5 August 2017

15

Emmanuel Nivet

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5 August 2017

17

Rupa Devi Soligalla

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5 August 2017

18

April Goebl

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5 August 2017

19

Emi Aizawa

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5 August 2017

22

Ilir Dubova

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5 August 2017

1

Guang-Hui Liu

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5 August 2017

Nongluk Plongthongkum

12

Nongluk Plongthongkum

1 reference

5 August 2017

Keiichiro Suzuki

2

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5 August 2017

Mo Li

3

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5 August 2017

Jing Qu

4

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5 August 2017

Ying Gu

7

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5 August 2017

Fei Yi

8

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5 August 2017

Xiuling Xu

9

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5 August 2017

Weiqi Zhang

10

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5 August 2017

Sergio Ruiz

11

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5 August 2017

Kun Zhang

13

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5 August 2017

Shigeo Masuda

14

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5 August 2017

Na Young Kim

20

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5 August 2017

Jessica Kim

21

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5 August 2017

Ying Li

23

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5 August 2017

Chris Benner

25

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5 August 2017

Juan Pablo Trujillo

28

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5 August 2017

Carlo Dufour

31

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5 August 2017

Concepcion Rodriguez Esteban

32

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5 August 2017

language of work or name

English

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publication date

7 July 2014

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5 August 2017

published in

Nature Communications

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5 August 2017

volume

5

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5 August 2017

page(s)

4330

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FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Differential analysis of gene regulation at transcript resolution with RNA-seq

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

FLASH assembly of TALENs for high-throughput genome editing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Fast gapped-read alignment with Bowtie 2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Overcoming reprogramming resistance of Fanconi anemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Library-free methylation sequencing with bisulfite padlock probes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Modelling schizophrenia using human induced pluripotent stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

A more efficient method to generate integration-free human iPS cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

The phenotype of FancB-mutant mouse embryonic stem cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Origin, functional role, and clinical impact of Fanconi anemia FANCA mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

BEDTools: a flexible suite of utilities for comparing genomic features

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Development of lentiviral vectors with optimized transcriptional activity for the gene therapy of patients with Fanconi anemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

How the fanconi anemia pathway guards the genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Mouse models of Fanconi anemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Distinct roles of stress-activated protein kinases in Fanconi anemia-type C-deficient hematopoiesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

The Fanconi anemia/BRCA gene network in zebrafish: embryonic expression and comparative genomics.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Model-based analysis of ChIP-Seq (MACS)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Highly efficient transient gene expression and gene targeting in primate embryonic stem cells with helper-dependent adenoviral vectors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Role of Fanconi DNA repair pathway in neural stem cell homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Fanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Hypomorphic mutations in the gene encoding a key Fanconi anemia protein, FANCD2, sustain a significant group of FA-D2 patients with severe phenotype

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

The Fanconi anemia group A protein modulates homologous repair of DNA double-strand breaks in mammalian cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Helper-dependent adenoviral vectors for gene therapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Physical and infectious titers of helper-dependent adenoviral vectors: a method of direct comparison to the adenovirus reference material

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Genome size and structure determine efficiency of postinternalization steps and gene transfer of capsid-modified adenovirus vectors in a cell-type-specific manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Origins of mammalian hematopoiesis: in vivo paradigms and in vitro models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Arrest of S-phase progression is impaired in Fanconi anemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice

8 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Deficient Regulation of DNA Double-strand Break Repair in Fanconi Anemia Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

FA iPS: correction or reprogramming first?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

A common founder mutation in FANCA underlies the world's highest prevalence of Fanconi anemia in Gypsy families from Spain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Danazol as first-line therapy for aplastic anemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Shared genetic susceptibility to breast cancer, brain tumors, and Fanconi anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Hematoendothelial differentiation of human embryonic stem cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291073

Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact

26 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS5330

Hypoxia enhances the generation of induced pluripotent stem cells

21 January 2018

1 reference

12 December 2020

UV-repair is impaired in fibroblasts from patients with Fanconi's anemia

1 reference

12 December 2020

Bone marrow microenvironment in fanconi anemia: a prospective functional study in a cohort of fanconi anemia patients

1 reference

12 December 2020

Antiinflammatory effects of Tremulacin, a Salicin-related substance isolated from Populus tomentosa Carr. leaves

1 reference

12 December 2020

Association of complementation group and mutation type with clinical outcome in fanconi anemia. European Fanconi Anemia Research Group

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS5330

1 reference

Dimensions Publication ID

5 August 2017

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5 August 2017

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