(Q34940857)

English

The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

The in vivo susceptibility of Leishmania donovani to sodium stibogluconate is drug specific and can be reversed by inhibiting glutathione biosynthesis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

based on heuristic

inferred from title

sodium stibogluconate

1 reference

based on heuristic

inferred from title

Leishmania donovani

object named as

Leishmania donovani

1 reference

based on heuristic

inferred from title

Corinne M Spickett

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

author name string

K C Carter

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

S Sundar

2

1 reference

Europe PubMed Central

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2 November 2019

O C Pereira

4

1 reference

Europe PubMed Central

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2 November 2019

A B Mullen

5

1 reference

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2 November 2019

language of work or name

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publication date

1 May 2003

1 reference

Europe PubMed Central

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2 November 2019

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

47

1 reference

Europe PubMed Central

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2 November 2019

1529-1535

1 reference

Europe PubMed Central

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2 November 2019

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

ABC proteins of Leishmania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Efficacies of vesicular and free sodium stibogluconate formulations against clinical isolates of Leishmania donovani

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Monitoring drug resistance in leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Targeting polyamines of parasitic protozoa in chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Glutathione-induced conversion of pentavalent antimony to trivalent antimony in meglumine antimoniate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Treatment of visceral leishmaniasis (kala-azar): a decade of progress and future approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Inhibition of glutathione synthesis as a chemotherapeutic strategy for leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Efficacy of second line drugs on antimonyl-resistant amastigotes of Leishmania infantum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Changes in sensitivity of a human myeloid cell line (U937) to metal toxicity after glutathione depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Gene amplification in Leishmania tarentolae selected for resistance to sodium stibogluconate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Co-amplification of the gamma-glutamylcysteine synthetase gene gsh1 and of the ABC transporter gene pgpA in arsenite-resistant Leishmania tarentolae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Trypanothione reductase from Leishmania donovani. Purification, characterisation and inhibition by trivalent antimonials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Toxicity of antimony and its compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

The therapeutic effect of sodium stibogluconate in BALB/c mice infected with Leishmania donovani is organ-dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

8 July 2018

Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Resistance of human multidrug resistance-associated protein 1-overexpressing lung tumor cells to the anticancer drug arsenic trioxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Novel Intracellular SbV reducing activity correlates with antimony susceptibility in Leishmania donovani.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Visceral leishmanicidal activity of hexadecylphosphocholine (miltefosine) in mice deficient in T cells and activated macrophage microbicidal mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Elevated levels of polyamines and trypanothione resulting from overexpression of the ornithine decarboxylase gene in arsenite-resistant Leishmania.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Comparison of the efficacy of free and non-ionic-surfactant vesicular formulations of paromomycin in a murine model of visceral leishmaniasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Effects of antimony on rats following 90-day exposure via drinking water.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=153333

26 October 2018

Energy-dependent efflux from Leishmania promastigotes of substrates of the mammalian multidrug resistance pumps

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania

1 reference

https://pubmed.ncbi.nlm.nih.gov/12709318

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.47.5.1529-1535.2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12709318%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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