(Q34955791)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

0 references

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1

Marija Tadin-Strapps

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Laurence B Peterson

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Anne-Marie Cumiskey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Raymond L Rosa

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Vivienne Halili Mendoza

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jose Castro-Perez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Liwen Zhang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Walter R Strapps

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Satyasri Yendluri

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Lori Andrews

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Victoria Pickering

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Julie Rice

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Lily Luo

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Zhu Chen

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Samnang Tep

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Brandon Ason

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Elizabeth Polizzi Somers

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Alan B Sachs

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Steven R Bartz

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jenny Tian

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jayne Chin

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Brian K Hubbard

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Kenny K Wong

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Lyndon J Mitnaul

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

publication date

11 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

Journal of Lipid Research

25 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

52

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

1084-1097

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

MicroRNA-like off-target transcript regulation by siRNAs is species specific.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

RNAi therapeutics: principles, prospects and challenges

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Familial hypobetalipoproteinemia: genetics and metabolism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Perspective: machines for RNAi

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

A comprehensive classification system for lipids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

A simple method for the isolation and purification of total lipides from animal tissues

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Summaries of Affymetrix GeneChip probe level data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Current perspectives on statins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Familial apolipoprotein E deficiency

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

A receptor-mediated pathway for cholesterol homeostasis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090230

Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice

8 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

2000 George Lyman Duff Memorial Lecture: atherosclerosis is a liver disease of the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Prospective 10-year evaluation of hypobetalipoproteinemia in a cohort of 772 firefighters and cross-sectional evaluation of hypocholesterolemia in 1,479 men in the National Health and Nutrition Examination Survey I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Comprehensive LC-MS E lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Regulation of hepatic cholesterol metabolism in CETP/LDLr mice by cholesterol feeding and by drugs (cholestyramine and lovastatin) that lower plasma cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

RNAi-mediated gene silencing in non-human primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Pre-filtering improves reliability of Affymetrix GeneChips results when used to analyze gene expression in complex tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M012872

Apolipoprotein E3-Leiden. A new variant of human apolipoprotein E associated with familial type III hyperlipoproteinemia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21398511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Plasma very low density lipoproteins contain a single molecule of apolipoprotein B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21398511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of acyl CoA: cholesterol acyltransferase inhibition on the uptake, esterification and secretion of cholesterol by the hamster small intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21398511

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M012872

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21398511%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

PubMed publication ID

21398511

1 reference