(Q34963775)

5 August 2017

title

Heme interacts with c1q and inhibits the classical complement pathway (English)

1 reference

Véronique Frémeaux-Bacchi

5 August 2017

author

7

Véronique Frémeaux-Bacchi

1 reference

5 August 2017

Jordan D Dimitrov

8

0 references

Lubka T. Roumenina

Lubka T Roumenina

Sébastien Lacroix-Desmazes

1

0 references

Sébastien Lacroix-Desmazes

6

0 references

Srini V Kaveri

5

Srinivas V Kaveri

1 reference

5 August 2017

3

Boris P Atanasov

1 reference

5 August 2017

Maria Radanova

2

1 reference

5 August 2017

Krastio T Popov

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

22 March 2011

1 reference

Journal of Biological Chemistry

5 August 2017

published in

1 reference

5 August 2017

volume

286

1 reference

5 August 2017

issue

18

1 reference

5 August 2017

page(s)

16459-16469

1 reference

Complement: a key system for immune surveillance and homeostasis

5 August 2017

cites work

1 reference

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8 July 2018

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Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage

8 July 2018

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Target pattern recognition by complement proteins of the classical and alternative pathways

8 July 2018

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8 July 2018

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Pattern recognition by pentraxins

21 January 2018

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8 July 2018

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Complement activation and inhibition: a delicate balance.

8 July 2018

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Hematin promotes complement alternative pathway-mediated deposition of C3 activation fragments on human erythrocytes: potential implications for the pathogenesis of anemia in malaria

8 July 2018

1 reference

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8 July 2018

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Targeting C-reactive protein for the treatment of cardiovascular disease.

8 July 2018

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Interaction of C1q with IgG1, C-reactive protein and pentraxin 3: mutational studies using recombinant globular head modules of human C1q A, B, and C chains

8 July 2018

1 reference

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Free heme toxicity and its detoxification systems in human

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Structure and activation of the C1 complex of complement: unraveling the puzzle.

8 July 2018

1 reference

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The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties

8 July 2018

1 reference

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Different faces of the heme-heme oxygenase system in inflammation

8 July 2018

1 reference

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Therapeutic inhibition of the early phase of complement activation

8 July 2018

1 reference

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Specific inhibition of the classical complement pathway by C1q-binding peptides.

8 July 2018

1 reference

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C1-inhibitor: an anti-inflammatory reagent with therapeutic potential

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Human C-reactive protein: expression, structure, and function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Complement. Second of two parts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Complement. First of two parts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Topology and structure of the C1q-binding site on C-reactive protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction

8 July 2018

1 reference

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The physiological structure of human C-reactive protein and its complex with phosphocholine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Principles of protein-protein recognition from structure to thermodynamics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Endothelial-cell heme uptake from heme proteins: induction of sensitization and desensitization to oxidant damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

A unique property of a plasma proteoglycan, the C1q inhibitor. An anticoagulant state resulting from its binding to fibrinogen

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Disposal of plasma heme in normal man and patients with intravascular hemolysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

The interaction of the factor VIII/von Willebrand factor complex with hematin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Cell membranes and liposomes dissociate C-reactive protein (CRP) to form a new, biologically active structural intermediate: mCRP(m).

8 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

In stroke, complement will get you nowhere

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Pro-oxidant and cytotoxic effects of circulating heme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Ultra-fast FFT protein docking on graphics processors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Effect of modified C-reactive protein on complement activation: a possible complement regulatory role of modified or monomeric C-reactive protein in atherosclerotic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Studies on the interactions between C-reactive protein and complement proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Calculation of entropy changes in biological processes: folding, binding, and oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Complement C1q-target proteins recognition is inhibited by electric moment effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Inhibition of classical pathway of complement activation with negative charged derivatives of bisphenol A and bisphenol disulphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Selective inhibition of the interaction of C1q with immunoglobulins and the classical pathway of complement activation by steroids and triterpenoids sulfates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091251

Dissociation of Pentameric to Monomeric C-Reactive Protein on Activated Platelets Localizes Inflammation to Atherosclerotic Plaques

26 October 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Role of Ca2+in the Electrostatic Stability and the Functional Activity of the Globular Domain of Human C1q†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Protein−Protein Interactions: Interface Structure, Binding Thermodynamics, and Mutational Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.206136

Antibodies use heme as a cofactor to extend their pathogen elimination activity and to acquire new effector functions

21 January 2018

1 reference

12 December 2020

Iron ions and haeme modulate the binding properties of complement subcomponent C1q and of immunoglobulins

1 reference

12 December 2020

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

1 reference

12 December 2020

Protective role of unconjugated bilirubin on complement-mediated hepatocytolysis

1 reference

12 December 2020

Transition towards antigen-binding promiscuity of a monospecific antibody

1 reference

12 December 2020

Cofactor-mediated protein promiscuity

1 reference

12 December 2020

The histidine-rich glycoprotein of serum has a domain rich in histidine, proline, and glycine that binds heme and metals

1 reference

12 December 2020

Inhibitory effect of bilirubin on complement-mediated hemolysis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.206136

1 reference

5 August 2017

1 reference

5 August 2017

1 reference