(Q34970853)

5 August 2017

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title

Molecular machinery required for autophagy and the cytoplasm to vacuole targeting (Cvt) pathway in S. cerevisiae (English)

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5 August 2017

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2

Daniel J Klionsky

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author name string

Waheeda A Khalfan

series ordinal

1

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5 August 2017

1 August 2002

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Current Opinion in Cell Biology

5 August 2017

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5 August 2017

14

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5 August 2017

468-475

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5 August 2017

4

1 reference

Autophagy in yeast: mechanistic insights and physiological function

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Vacuolar import of proteins and organelles from the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Concepts of cell death and application to carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

TOR, a central controller of cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

The target of rapamycin (TOR) proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Analyses of APG13 gene involved in autophagy in yeast, Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Dissection of autophagosome biogenesis into distinct nucleation and expansion steps

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Yol082p, a novel CVT protein involved in the selective targeting of aminopeptidase I to the yeast vacuole.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm to vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Autophagy and the cvt pathway both depend on AUT9.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg2 is a novel protein required for the cytoplasm to vacuole targeting, autophagy, and pexophagy pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg2p functions in autophagosome formation on the perivacuolar structure

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Molecular dissection of autophagy: two ubiquitin-like systems

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A protein conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A ubiquitin-like system mediates protein lipidation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Membrane recruitment of Aut7p in the autophagy and cytoplasm to vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

The C-terminal region of an Apg7p/Cvt2p is required for homodimerization and is essential for its E1 activity and E1-E2 complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Formation process of autophagosome is traced with Apg8/Aut7p in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Acidification of vacuoles is required for autophagic degradation in the yeast, Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Degradation and turnover of peroxisomes in the yeast Hansenula polymorpha induced by selective inactivation of peroxisomal enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

GSA11 encodes a unique 208-kDa protein required for pexophagy and autophagy in Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Peroxisome biogenesis and selective degradation converge at Pex14p

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

A Pichia pastoris VPS15 homologue is required in selective peroxisome autophagy

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2802%2900343-5

7 January 2021

10.1016/S0955-0674(02)00343-5

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12383798