(Q34981800)

English

Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Alvaro Inglés-Prieto

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

José A. Gavira

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Jose Manuel Sanchez Ruiz

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Valeria A Risso

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Fadia Manssour-Triedo

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Asunción Delgado-Delgado

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Rocio Arco

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Alicia Barroso-delJesus

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Raquel Godoy-Ruiz

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Eric A Gaucher

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Beatriz Ibarra-Molero

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

12 November 2014

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Molecular Biology and Evolution

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

32

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

440-455

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Biophysics of protein evolution and evolutionary protein biophysics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

An experimentally determined evolutionary model dramatically improves phylogenetic fit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Strong evidence for protein epistasis, weak evidence against it.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Evolutionary history and metabolic insights of ancient mammalian uricases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Mutational effects on stability are largely conserved during protein evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Conservation of Protein Structure over Four Billion Years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

The evolutionary origins of detoxifying enzymes: the mammalian serum paraoxonases (PONs) relate to bacterial homoserine lactonases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Experimental evidence for the thermophilicity of ancestral life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

The origin of membrane bioenergetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Reconstruction of ancestral metabolic enzymes reveals molecular mechanisms underlying evolutionary innovation through gene duplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Amino acid coevolution induces an evolutionary Stokes shift.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Evolution of increased complexity in a molecular machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Estimating the distribution of selection coefficients from phylogenetic data using sitewise mutation-selection models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

On the origin and evolution of thermophily: reconstruction of functional precambrian enzymes from ancestors of Bacillus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Natural evolution of TEM-1 β-lactamase: experimental reconstruction and clinical relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Mutation-selection models of coding sequence evolution with site-heterogeneous amino acid fitness profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Inferring relative proportions of DNA variants from sequencing electropherograms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Chaperonin overexpression promotes genetic variation and enzyme evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A class frequency mixture model that adjusts for site-specific amino acid frequencies and improves inference of protein phylogeny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

High tolerance for ionizable residues in the hydrophobic interior of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Phylogenetic mixture models for proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Increased folding stability of TEM-1 beta-lactamase by in vitro selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Crystal structure of an ancient protein: evolution by conformational epistasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

The stability effects of protein mutations appear to be universally distributed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Breaking proteins with mutations: threads and thresholds in evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Molecular paleoscience: systems biology from the past.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Darwinian evolution can follow only very few mutational paths to fitter proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Long-term survival during stationary phase: evolution and the GASP phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Thermodynamic prediction of protein neutrality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A global suppressor motif for p53 cancer mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A Bayesian mixture model for across-site heterogeneities in the amino-acid replacement process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Proteomic analysis of thioredoxin-targeted proteins in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Paleoproterozoic snowball earth: extreme climatic and geochemical global change and its biological consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Calibrating bacterial evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A neoproterozoic snowball earth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Evolutionary distances for protein-coding sequences: modeling site-specific residue frequencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A helix propensity scale based on experimental studies of peptides and proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A natural polymorphism in beta-lactamase is a global suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A direct comparison of helix propensity in proteins and peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

A thermodynamic scale for the beta-sheet forming tendencies of the amino acids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Natural Selection and the Concept of a Protein Space

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Genetic analysis of staphylococcal nuclease: identification of three intragenic "global" suppressors of nuclease-minus mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Amino acid preferences for specific locations at the ends of alpha helices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

The thermodynamic stability of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Phage lambda repressor revertants. Amino acid substitutions that restore activity to mutant proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

8 July 2018

Palaeotemperature trend for Precambrian life inferred from resurrected proteins

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Natural selection for kinetic stability is a likely origin of correlations between mutational effects on protein energetics and frequencies of amino acid occurrences in sequence alignments.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Relation between protein stability, evolution and structure, as probed by carboxylic acid mutations.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Hydrophobic environment is a key factor for the stability of thermophilic proteins

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Thermodynamic beta-sheet propensities measured using a zinc-finger host peptide.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Modulation of buried ionizable groups in proteins with engineered surface charge.

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Thermostable and promiscuous Precambrian proteins

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

GroEL/ES buffering and compensatory mutations promote protein evolution by stabilizing folding intermediates

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Step-wise mutation of barnase to binase. A procedure for engineering increased stability of proteins and an experimental analysis of the evolution of protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298172

26 October 2018

Alternative packing arrangements in the hydrophobic core of λrepresser

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSU312

21 January 2018

Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/25392342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global suppression of protein folding defects and inclusion body formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25392342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helix stop signals in proteins and peptides: the capping box

1 reference

https://pubmed.ncbi.nlm.nih.gov/25392342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why are proteins marginally stable?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25392342

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/MOLBEV/MSU312

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25392342%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34981800&oldid=1966807979"