(Q34991840)

5 August 2017

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title

The role of cytokines in liver failure and regeneration: potential new molecular therapies (English)

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5 August 2017

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1

Eithan Galun

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author name string

Jonathan H Axelrod

series ordinal

2

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PubMed ID

12421677

5 August 2017

language of work or name

English

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publication date

1 November 2002

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Biochimica et Biophysica Acta

5 August 2017

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5 August 2017

1592

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5 August 2017

3

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5 August 2017

345-358

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Initiation of mammalian liver development from endoderm by fibroblast growth factors

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Identification of a bipotential precursor cell in hepatic cell lines derived from transgenic mice expressing cyto-Met in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Molecular mechanisms of liver development and differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Bone marrow as a potential source of hepatic oval cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Cooperation between STAT3 and c-jun suppresses Fas transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Fulminant and subfulminant liver failure: definitions and causes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Etiology and outcome for 295 patients with acute liver failure in the United States.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

East meets West: acute liver failure in the global village

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

1 reference

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

1 reference

7 January 2021

Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

The effect of N-acetylcysteine on oxygen transport and uptake in patients with fulminant hepatic failure.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Treatment of fulminant hepatic failure with intravenous prostaglandin E1.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Liver assist systems: state of the art.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Growth and metabolic activity of immortalized porcine hepatocytes in extracorporeal hollow-fiber liver assist devices

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Use of MARS in the treatment of acute liver failure: preliminar monocentric experience

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocyte transplantation in acute liver failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocyte growth factor: a multifunctional cytokine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Animal models of fulminant hepatic failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Animal models of acute hepatic failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hyper-IL-6 gene therapy reverses fulminant hepatic failure.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Experimental hepatitis induced by D-galactosamine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Glycine and uridine prevent D-galactosamine hepatotoxicity in the rat: role of Kupffer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Role of nitric oxide in acetaminophen-induced hepatotoxicity in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hypothyroidism minimizes liver damage and improves survival in rats with thioacetamide induced fulminant hepatic failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Pentoxifylline prevents concanavalin A-induced hepatitis by reducing tumor necrosis factor alpha levels and inhibiting adhesion of T lymphocytes to extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

A T cell-dependent experimental liver injury in mice inducible by concanavalin A

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Involvement of intrasinusoidal hemostasis in the development of concanavalin A-induced hepatic injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

TNF-alpha-induced expression of adhesion molecules in the liver is under the control of TNFR1--relevance for concanavalin A-induced hepatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Lethal hepatitis after gene transfer of IL-4 in the liver is independent of immune responses and dependent on apoptosis of hepatocytes: a rodent model of IL-4-induced hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Low-molecular-weight hyaluronic acid induces nuclear factor-kappaB-dependent resistance against tumor necrosis factor alpha-mediated liver injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

CD44-deficient mice exhibit enhanced hepatitis after concanavalin A injection: evidence for involvement of CD44 in activation-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Critical contribution of liver natural killer T cells to a murine model of hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Contribution of Fas ligand to T cell-mediated hepatic injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Complete reconstitution of mouse liver with xenogeneic hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Liver repopulation for the treatment of metabolic diseases.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Loss of p27(Kip1) enhances the transplantation efficiency of hepatocytes transferred into diseased livers

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

1 reference

7 January 2021

Complete hepatic regeneration after somatic deletion of an albumin-plasminogen activator transgene

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Replacement of diseased mouse liver by hepatic cell transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

The repopulation potential of hepatocyte populations differing in size and prior mitotic expansion

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

1 reference

7 January 2021

Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Liver from bone marrow in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocytes from non-hepatic adult stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Cytokine regulation of liver injury and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Obesity increases sensitivity to endotoxin liver injury: implications for the pathogenesis of steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Regulation of mitogenesis by kinins in arterial smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kappaB

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

NF-kappaB determines between apoptosis and proliferation in hepatocytes during liver regeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hyperstimulation with interleukin 6 inhibits cell cycle progression after hepatectomy in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Expression of suppressors of cytokine signaling during liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Activation of interleukin-6/STAT3 and liver regeneration following transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Blocking NF-kappaB in the liver: the good and bad news

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukin-6-induced STAT3 and AP-1 amplify hepatocyte nuclear factor 1-mediated transactivation of hepatic genes, an adaptive response to liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Ischemic preconditioning protects the mouse liver by inhibition of apoptosis through a caspase-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Delayed Fas-mediated hepatocyte apoptosis during liver regeneration in mice: hepatoprotective role of TNF alpha.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Fas engagement accelerates liver regeneration after partial hepatectomy

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

NFkappaB prevents apoptosis and liver dysfunction during liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Protective effect of preconditioning on the injury associated to hepatic ischemia-reperfusion in the rat: Role of nitric oxide and adenosine

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukins 6 and 11 protect mice from mortality in a staphylococcal enterotoxin-induced toxic shock model

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Injection time of interleukin-6 determines fatal outcome in experimental endotoxin shock

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukin-6 inhibits transforming growth factor-beta-induced apoptosis through the phosphatidylinositol 3-kinase/Akt and signal transducers and activators of transcription 3 pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukin-6 protects against Fas-mediated death by establishing a critical level of anti-apoptotic hepatic proteins FLIP, Bcl-2, and Bcl-xL.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocyte growth factor in transgenic mice: effects on hepatocyte growth, liver regeneration and gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatocyte growth factor prevents endotoxin-induced lethal hepatic failure in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Adenovirus-mediated hepatocyte growth factor gene transfer prevents lethal liver failure in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme-linked immunosorbent assay

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Serum hepatocyte growth factor levels in liver diseases: clinical implications

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

D-galactosamine-induced mouse hepatic apoptosis: possible involvement with tumor necrosis factor, but not with caspase-3 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatitis G virus infection in acute fulminant hepatitis: prevalence of HGV infection and sequence analysis of a specific viral strain

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

A dog model for acetaminophen-induced fulminant hepatic failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

The hydroxyl radical scavengers dimethylsulfoxide and dimethylthiourea protect rats against thioacetamide-induced fulminant hepatic failure

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: characterization of an improved model and study of amino acid-ergic neurotransmission

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Murine concanavalin A-induced hepatitis is prevented by interleukin 12 (IL-12) antibody and exacerbated by exogenous IL-12 through an interferon-gamma-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

A broad-spectrum caspase inhibitor blocks concanavalin A-induced hepatitis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Concanavalin A simultaneously primes liver hematopoietic and epithelial progenitor cells for parallel expansion during liver regeneration after partial hepatectomy in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Inhibition of concanavalin A-induced acute T cell dependent hepatic damage in mice by hypothyroidism

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Interleukin 1beta protects mice from Fas-mediated hepatocyte apoptosis and death

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Lethal effect of the anti-Fas antibody in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Fulminant hepatitis by Fas-ligand expression in MRL-lpr/lpr mice grafted with Fas-positive livers and wild-type mice with Fas-mutant livers

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Adenovirus-mediated gene transfer in rat liver of interleukin 4 but not interleukin 10 produces severe acute hepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Keratinocyte growth factor protects murine hepatocytes from tumor necrosis factor-induced apoptosis in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Etoposide prevents apoptosis in mouse liver with D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure resulting in reduction of lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Bacterial endotoxin enhances the hepatotoxicity of allyl alcohol

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

Impaired liver regeneration in inducible nitric oxide synthasedeficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900326-9

7 January 2021

10.1016/S0167-4889(02)00326-9

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12421677