(Q34995002)

5 August 2017

1 reference

title

Development of new treatments for Parkinson's disease in transgenic animal models: a role for beta-synuclein (English)

1 reference

5 August 2017

1 reference

1 reference

1

Eliezer Masliah

1 reference

5 August 2017

Makoto Hashimoto

2

1 reference

5 August 2017

publication date

1 October 2002

1 reference

5 August 2017

1 reference

5 August 2017

volume

23

1 reference

5 August 2017

issue

4-5

1 reference

5 August 2017

page(s)

461-468

1 reference

Parkinson's disease-associated alpha-synuclein is more fibrillogenic than beta- and gamma-synuclein and cannot cross-seed its homologs

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Review: formation and properties of amyloid-like fibrils derived from alpha-synuclein and related proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

A Drosophila model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Trans-suppression of misfolding in an amyloid disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Human recombinant NACP/alpha-synuclein is aggregated and fibrillated in vitro: relevance for Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Alpha-synuclein in Lewy body disease and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Role of cytochrome c as a stimulator of alpha-synuclein aggregation in Lewy body disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

alpha-synuclein promotes mitochondrial deficit and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Properties of NACP/alpha-synuclein and its role in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Identification of two distinct synucleins from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

alpha-Synuclein membrane interactions and lipid specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Amyloid diseases: abnormal protein aggregation in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

The ubiquitin pathway in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Recent advances in the understanding of the role of synaptic proteins in Alzheimer's Disease and other neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

A new brain-specific 14-kDa protein is a phosphoprotein. Its complete amino acid sequence and evidence for phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Intracellular polymerization. Disease severity and therapeutic predictions

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Self-oligomerization of NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer's disease amyloid, observed in the presence of a C-terminal A beta fragment (residues 25-35).

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Copper(II)-induced self-oligomerization of alpha-synuclein.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Interaction of human alpha-Synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Oxidative damage and protection by antioxidants in the frontal cortex of Alzheimer's disease is related to the apolipoprotein E genotype

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Fiber diffraction of synthetic alpha-synuclein filaments shows amyloid-like cross-beta conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Synoretin--A new protein belonging to the synuclein family

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Expression of mutant alpha-synuclein causes increased susceptibility to dopamine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900029-3

7 January 2021

10.1016/S0161-813X(02)00029-3

Identifiers

DOI

1 reference

5 August 2017

1 reference