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Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
main subject
molecular chaperones
0 references
proteolysis
1 reference
based on heuristic
inferred from title
author name string
Ferrigno P
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
Silver PA
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
language of work or name
English
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publication date
1 April 2000
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
published in
Neuron
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stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
volume
26
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
page(s)
9-12
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
cites work
A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast
1 reference
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Crossref
reference URL
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7 January 2021
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Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
1 reference
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Crossref
reference URL
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7 January 2021
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Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
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Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
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inferred from DOI database lookup
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
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inferred from DOI database lookup
Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Characterization and localization of the Huntington disease gene product
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Crossref
reference URL
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7 January 2021
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Genetic suppression of polyglutamine toxicity in Drosophila
1 reference
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Crossref
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7 January 2021
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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
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inferred from DOI database lookup
Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
A cellular model that recapitulates major pathogenic steps of Huntington's disease
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Crossref
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7 January 2021
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inferred from DOI database lookup
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
1 reference
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Crossref
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7 January 2021
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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
1 reference
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7 January 2021
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Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8 is required for cell death induced by expanded polyglutamine repeats.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0896-6273%2800%2981132-0
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0896-6273(00)81132-0
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
PubMed ID
10798387
1 reference
stated in
Europe PubMed Central
PubMed ID
10798387
retrieved
30 July 2017
ResearchGate publication ID
247266946
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