(Q33911146)

30 July 2017

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title

Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity (English)

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30 July 2017

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Ferrigno P

1

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30 July 2017

Silver PA

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 April 2000

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30 July 2017

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30 July 2017

volume

26

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30 July 2017

issue

1

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30 July 2017

page(s)

9-12

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A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast

30 July 2017

cites work

1 reference

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Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

1 reference

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7 January 2021

Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease

1 reference

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7 January 2021

Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

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7 January 2021

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

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7 January 2021

Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor

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7 January 2021

Characterization and localization of the Huntington disease gene product

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7 January 2021

Genetic suppression of polyglutamine toxicity in Drosophila

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7 January 2021

Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

1 reference

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7 January 2021

Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins

1 reference

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7 January 2021

Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin

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7 January 2021

Polyglutamine expansion down-regulates specific neuronal genes before pathologic changes in SCA1.

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7 January 2021

A cellular model that recapitulates major pathogenic steps of Huntington's disease

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7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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7 January 2021

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

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7 January 2021

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

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7 January 2021

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases

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7 January 2021

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

1 reference

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7 January 2021

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

1 reference

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7 January 2021

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

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10.1016/S0896-6273(00)81132-0

Identifiers

DOI

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30 July 2017

1 reference