(Q34998995)

5 August 2017

title

NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease (English)

1 reference

5 August 2017

0 references

C A Colton

1

1 reference

5 August 2017

M P Vitek

2

1 reference

5 August 2017

D A Wink

3

1 reference

5 August 2017

Q Xu

4

1 reference

5 August 2017

V Cantillana

5

1 reference

5 August 2017

M L Previti

6

1 reference

5 August 2017

W E Van Nostrand

7

1 reference

5 August 2017

J B Weinberg

8

1 reference

5 August 2017

H Dawson

9

1 reference

5 August 2017

language of work or name

English

0 references

publication date

14 August 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

5 August 2017

volume

103

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5 August 2017

issue

34

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5 August 2017

page(s)

12867-12872

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Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

5 August 2017

cites work

1 reference

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8 July 2018

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8 July 2018

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8 July 2018

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Resident microglia from adult mice are refractory to nitric oxide-inducing stimuli due to impaired NOS2 gene expression

8 July 2018

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8 July 2018

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8 July 2018

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Hypoxic inducible factor 1alpha, extracellular signal-regulated kinase, and p53 are regulated by distinct threshold concentrations of nitric oxide.

8 July 2018

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Nitric oxide and its role in ischaemic brain injury

8 July 2018

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

8 July 2018

1 reference

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Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

8 July 2018

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The metallobiology of Alzheimer's disease

8 July 2018

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Apoptosis and caspases in neurodegenerative diseases

8 July 2018

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Natural cellular inhibitors of caspases

8 July 2018

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Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics

8 July 2018

1 reference

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Protein nitration is mediated by heme and free metals through Fenton-type chemistry: an alternative to the NO/O2- reaction

8 July 2018

1 reference

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Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

8 July 2018

1 reference

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

8 July 2018

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The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases

8 July 2018

1 reference

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S-Nitrosylation of mitochondrial caspases

8 July 2018

1 reference

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

8 July 2018

1 reference

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

8 July 2018

1 reference

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Aberrant expression of nitric oxide synthase III in Alzheimer's disease: relevance to cerebral vasculopathy and neurodegeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

8 July 2018

1 reference

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Inducible nitric oxide synthase is an endogenous neuroprotectant after traumatic brain injury in rats and mice

8 July 2018

1 reference

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Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide

8 July 2018

1 reference

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Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms

8 July 2018

1 reference

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

8 July 2018

1 reference

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

Activation of microglial cells by beta-amyloid protein and interferon-gamma.

8 July 2018

1 reference

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Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.

8 July 2018

1 reference

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Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death

8 July 2018

1 reference

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Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Nitric oxide in the cerebral cortex of amyloid-precursor protein (SW) Tg2576 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Aberrant expression of NOS isoforms in Alzheimer's disease is structurally related to nitrotyrosine formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Reducing cerebral microvascular amyloid-beta protein deposition diminishes regional neuroinflammation in vasculotropic mutant amyloid precursor protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Inflammation and Alzheimer's disease: relationships between pathogenic mechanisms and clinical expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Fibrillary beta-amyloid deposits are closely associated with atrophic nitric oxide synthase (NOS)-expressing neurons but do not upregulate the inducible NOS in transgenic Tg2576 mouse brain with Alzheimer pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Pathological consequences of inducible nitric oxide synthase expression in hippocampal slice cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Nitric oxide inhibits caspase activation and apoptotic morphology but does not rescue neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

ELISA method for measurement of amyloid-beta levels.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

Adverse effect of a presenilin-1 mutation in microglia results in enhanced nitric oxide and inflammatory cytokine responses to immune challenge in the brain

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

Microglial contribution to oxidative stress in Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

Widespread peroxynitrite-mediated damage in Alzheimer's disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1550768

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

26 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0601075103

Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16908860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0601075103

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference