(Q35002007)

5 August 2017

title

Targeting oncogenic interleukin-7 receptor signalling with N-acetylcysteine in T cell acute lymphoblastic leukaemia (English)

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5 August 2017

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5

Jean-Claude Twizere

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Amy R Eisenberg

Amy R Eisenberg

3

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Marc Mansour

Marc R Mansour

1

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Andrew L. Kung

Andrew L Kung

16

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David M Weinstock

14

David M Weinstock

1 reference

5 August 2017

Casie Reed

2

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5 August 2017

Jen-Chieh Tseng

4

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5 August 2017

Sarah Daakour

6

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5 August 2017

Akinori Yoda

7

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5 August 2017

Scott J Rodig

8

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5 August 2017

Noa Tal

9

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5 August 2017

Chen Shochat

10

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5 August 2017

Alla Berezovskaya

11

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5 August 2017

Daniel J DeAngelo

12

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5 August 2017

Stephen E Sallan

13

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5 August 2017

Shai Izraeli

15

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5 August 2017

Alex Kentsis

17

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5 August 2017

A Thomas Look

18

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5 August 2017

language of work or name

English

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publication date

26 September 2014

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British Journal of Haematology

5 August 2017

published in

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5 August 2017

volume

168

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5 August 2017

issue

2

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5 August 2017

page(s)

230-238

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The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts

5 August 2017

cites work

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TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Activating HER2 mutations in HER2 gene amplification negative breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Labile disulfide bonds are common at the leucocyte cell surface.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Mutation of the receptor tyrosine phosphatase PTPRC (CD45) in T-cell acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Structural reorganization of the interleukin-7 signaling complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Benchmarking a luciferase complementation assay for detecting protein complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Functional screening identifies CRLF2 in precursor B-cell acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Structural and biophysical studies of the human IL-7/IL-7Ralpha complex

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Somatically acquired JAK1 mutations in adult acute lymphoblastic leukemia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Prevention of ifosfamide nephrotoxicity by N-acetylcysteine: clinical pharmacokinetic considerations.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Effect of high-dose intravenous N-acetylcysteine on the concentration of plasma sulfur-containing amino acids

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Biological and clinical significance of the JAK-STAT pathway; lessons from knockout mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Regulation of IL-2 signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Activation of phosphatidylinositol-3 kinase by ligation of the interleukin-7 receptor on human thymocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Pharmacokinetics of N-acetylcysteine in man.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Pharmacokinetics and bioavailability of oral acetylcysteine in healthy volunteers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Clinical pharmacokinetics of N-acetylcysteine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Acetaminophen overdose: a 48-hour intravenous N-acetylcysteine treatment protocol

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Reagents which inhibit disulphide bond formation stabilize human fibroblast interferon

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

Pharmacokinetics of intravenous N-acetylcysteine in men at rest and during exercise

8 July 2018

1 reference

Bone marrow chemoprotection without compromise of chemotherapy efficacy in a rat brain tumor model

21 January 2018

1 reference

Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States

21 January 2018

1 reference

Novel activating mutations lacking cysteine in type I cytokine receptors in acute lymphoblastic leukemia

21 January 2018

1 reference

Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

21 January 2018

1 reference

Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303513

26 October 2018

Stat5 tetramer formation is associated with leukemogenesis

21 January 2018

1 reference

Pharmacokinetics of intravenous N -acetylcysteine in pre-term new-born infants

21 January 2018

1 reference

12 December 2020

Toxicological Studies of 2-Mercaptoethanol

1 reference

12 December 2020

Treating acute acetaminophen poisoning with acetylcysteine

1 reference

12 December 2020

Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine

1 reference

12 December 2020

The disposition and kinetics of intravenous N-acetylcysteine in patients with paracetamol overdosage

1 reference

12 December 2020

JAK3 protein tyrosine kinase mediates interleukin-7-induced activation of phosphatidylinositol-3' kinase

1 reference

12 December 2020

Pharmacokinetics of N-acetylcysteine are altered in patients with chronic liver disease

1 reference

12 December 2020

Management of paracetamol poisoning

1 reference

12 December 2020

Identifiers

DOI

10.1111/BJH.13115

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5 August 2017

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5 August 2017

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