(Q43599325)

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Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

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scholarly article

1 reference

Europe PubMed Central

25 November 2017

Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells (English)

1 reference

Europe PubMed Central

25 November 2017

1 reference

based on heuristic

inferred from title

reactive oxygen species

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based on heuristic

inferred from title

lymphoblastic leukemia

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based on heuristic

inferred from title

T-cell acute lymphoblastic leukemia

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based on heuristic

inferred from title

João T. Barata

6

1 reference

Europe PubMed Central

25 November 2017

object named as

I Cebola

3

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Fernando Antunes

object named as

F Antunes

5

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author name string

A Silva

1

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Europe PubMed Central

25 November 2017

A Gírio

2

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Europe PubMed Central

25 November 2017

C I Santos

4

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Europe PubMed Central

25 November 2017

publication date

1 April 2011

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Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

25

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Europe PubMed Central

25 November 2017

6

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Europe PubMed Central

25 November 2017

960-967

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Europe PubMed Central

25 November 2017

https://scigraph.springernature.com/pub.10.1038/leu.2011.56

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Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis?

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice

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https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Haploinsufficiency identifies STAT5 as a modifier of IL-7-induced lymphomas

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species

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https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Constitutive phosphoinositide 3-kinase/Akt activation represents a favorable prognostic factor in de novo acute myelogenous leukemia patients.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Mechanisms of ROS modulated cell survival during carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Oxidants painting the cysteine chapel: redox regulation of PTPs

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https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Reversible inactivation of the tumor suppressor PTEN by H2O2

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https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

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https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Phosphorylation of the survival kinase Akt by superoxide is dependent on an ascorbate-reversible oxidation of PTEN.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Reactive oxygen species: role in the development of cancer and various chronic conditions

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Lysosomal enzymes promote mitochondrial oxidant production, cytochrome c release and apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Redox regulation of interleukin-4 signaling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Cytokine stimulation promotes glucose uptake via phosphatidylinositol-3 kinase/Akt regulation of Glut1 activity and trafficking

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Cell transformation by the superoxide-generating oxidase Mox1

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Regulation of T-cell apoptosis by reactive oxygen species.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Hydrogen peroxide: a signaling messenger

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Mitochondria: a hub of redox activities and cellular distress control

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Cross talk between mitochondria and superoxide generating NADPH oxidase in breast and ovarian tumors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Cross-talk between mitochondria and NADPH oxidase: effects of mild mitochondrial dysfunction on angiotensin II-mediated increase in Nox isoform expression and activity in vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

21 January 2018

Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

Link between mitochondria and NADPH oxidase 1 isozyme for the sustained production of reactive oxygen species and cell death

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

Downregulation of catalase by reactive oxygen species via PI 3 kinase/Akt signaling in mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/LEU.2011.56

1 reference

Europe PubMed Central

25 November 2017

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1 reference

Europe PubMed Central

25 November 2017

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