(Q36194601)

12 August 2017

1 reference

title

Interleukin-7 in T-cell acute lymphoblastic leukemia: an extrinsic factor supporting leukemogenesis? (English)

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T-cell acute lymphoblastic leukemia

12 August 2017

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lymphoblastic leukemia

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based on heuristic

inferred from title

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Joao T Barata

1

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author name string

Angelo A Cardoso

series ordinal

2

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12 August 2017

Vassiliki A Boussiotis

series ordinal

3

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12 August 2017

publication date

1 April 2005

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12 August 2017

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12 August 2017

volume

46

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12 August 2017

issue

4

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12 August 2017

page(s)

483-495

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Oncogenic transcription factors in the human acute leukemias

12 August 2017

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Jaks and STATs: biological implications

21 January 2018

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Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells.

21 January 2018

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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

21 January 2018

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Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

21 January 2018

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21 January 2018

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21 January 2018

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T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation.

21 January 2018

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21 January 2018

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Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Activation of p38 mitogen-activated protein kinase in vivo selectively induces apoptosis of CD8(+) but not CD4(+) T cells

21 January 2018

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The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

21 January 2018

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Activation of the p38 mitogen-activated protein kinase pathway arrests cell cycle progression and differentiation of immature thymocytes in vivo

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

21 January 2018

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c-Myb transcription is activated by protein kinase B (PKB) following interleukin 2 stimulation of Tcells and is required for PKB-mediated protection from apoptosis

21 January 2018

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Bad can act as a key regulator of T cell apoptosis and T cell development.

21 January 2018

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

21 January 2018

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Negative regulation of T cell proliferation and interleukin 2 production by the serine threonine kinase GSK-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

The Bcl-2 gene is differentially regulated by IL-2 and IL-4: role of the transcription factor NF-AT.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190400027852

Activation of NF-kappaB/Rel transcription factors in human primary peripheral blood mononuclear cells by interleukin 7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin-7 and interleukin-15 regulate the expression of the bcl-2 and c-myb genes in cutaneous T-cell lymphoma cells.

21 January 2018

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Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190400027852

IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL.

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190400027852

Loss of Smad3 in acute T-cell lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin-7 retroviruses transform pre-B cells by an autocrine mechanism not evident in Abelson murine

21 January 2018

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Cutaneous lymphoproliferation and lymphomas in interleukin 7 transgenic mice

21 January 2018

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Overexpression of IL-7R alpha provides a competitive advantage during early T-cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190400027852

Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus

21 January 2018

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https://api.crossref.org/works/10.1080%2F10428190400027852

Phosphorylation of the TAL1 oncoprotein by the extracellular-signal-regulated protein kinase ERK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Influence of antibodies against IGF-I, insulin or their receptors on proliferation of human acute lymphoblastic leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Interleukin 7 enhances cytolytic T lymphocyte generation and induces lymphokine-activated killer cells from human peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Retrovirus-mediated IL-7 expression in leukemic dendritic cells generated from primary acute myelogenous leukemias enhances their functional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

A new modality for immunosuppression: targeting the JAK/STAT pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Targeting the PI3K-Akt pathway in human cancer: rationale and promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Phosphatidylinositol-3 kinase inhibitors enhance the anti-leukemia effect of STI571.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Inhibition of phosphatidylinositol 3'-kinase induces preferentially killing of PTEN-null T leukemias through AKT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

Rapamycin blocks IL-2-driven T cell cycle progression while preserving T cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10428190400027852

10.1080/10428190400027852

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference