(Q35008186)

5 August 2017

title

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease (English)

1 reference

5 August 2017

9

1 reference

Spiros Artavanis-Tsakonas

5 August 2017

14

Cenk Ayata

0 references

16

object named as

Spyros Artavanis-Tsakonas

1 reference

5 August 2017

Jeong Hyun Lee

3

0 references

Steven P. Gygi

10

object named as

Steven Gygi

1 reference

5 August 2017

6

Charles R Vanderburg

1 reference

5 August 2017

7

Matthew P Frosch

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5 August 2017

author name string

Joseph F Arboleda-Velasquez

1

1 reference

5 August 2017

Jan Manent

2

1 reference

5 August 2017

Saara Tikka

4

1 reference

5 August 2017

Carolina Ospina

5

1 reference

5 August 2017

Manuel Rodríguez-Falcón

8

1 reference

5 August 2017

Francisco Lopera

11

1 reference

5 August 2017

Hannu Kalimo

12

1 reference

5 August 2017

Michael A Moskowitz

13

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5 August 2017

Angeliki Louvi

15

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5 August 2017

language of work or name

English

0 references

publication date

9 May 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

5 August 2017

published in

1 reference

5 August 2017

volume

108

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5 August 2017

issue

21

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5 August 2017

page(s)

E128-35

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Notch3 Is Critical for Proper Angiogenesis and Mural Cell Investment

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Chapter 6: The chaperone action of Clusterin and its putative role in quality control of extracellular protein folding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

8 July 2018

1 reference

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

The canonical Notch signaling pathway: unfolding the activation mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Living beyond our physiological means: small vessel disease of the brain is an expression of a systemic failure in arteriolar function: a unifying hypothesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Linking Notch signaling to ischemic stroke

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Notch signaling in blood vessels: who is talking to whom about what?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

CADASIL-causing mutations do not alter Notch3 receptor processing and activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

CADASIL: a critical look at a Notch disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

The spectrum of mutations for CADASIL diagnosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Notch3 is required for arterial identity and maturation of vascular smooth muscle cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

CADASIL-associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling through RBP-Jk

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Smooth muscle-selective deletion of guanylyl cyclase-A prevents the acute but not chronic effects of ANP on blood pressure

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Clusterin is a secreted mammalian chaperone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Notch signaling: cell fate control and signal integration in development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Generalized lacZ expression with the ROSA26 Cre reporter strain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Strong clustering and stereotyped nature of Notch3 mutations in CADASIL patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Laser capture microdissection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Role of COL4A1 in small-vessel disease and hemorrhagic stroke.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Hereditary multi-infarct dementia of the Swedish type is a novel disorder different from NOTCH3 causing CADASIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Systemic vascular smooth muscle cell impairment in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Autosomal dominant leukoencephalopathy and subcortical ischemic stroke. A clinicopathological study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Case records of the Massachusetts General Hospital. Case 12-2009. A 46-year-old man with migraine, aphasia, and hemiparesis and similarly affected family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Detection of the founder effect in Finnish CADASIL families

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Genetic, clinical and pathological studies of CADASIL in Japan: a partial contribution of Notch3 mutations and implications of smooth muscle cell degeneration for the pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Mice carrying a R142C Notch 3 knock-in mutation do not develop a CADASIL-like phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1101964108

Notch3 ectodomain is a major component of granular osmiophilic material (GOM) in CADASIL

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Morphometric analysis of ultrastructural vascular changes in CADASIL: analysis of 50 skin biopsy specimens and pathogenic implications.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102344

Fibrosis and stenosis of the long penetrating cerebral arteries: the cause of the white matter pathology in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21555590

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1101964108

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference