(Q35012216)

5 August 2017

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title

Recent advances in angiogenesis, anti-angiogenesis and vascular targeting (English)

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5 August 2017

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Andreas Bikfalvi

1

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PubMed ID

12457776

5 August 2017

Roy Bicknell

series ordinal

2

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5 August 2017

1 December 2002

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Trends in Pharmacological Sciences

5 August 2017

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5 August 2017

23

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5 August 2017

576-582

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5 August 2017

12

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Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Mechanisms of angiogenesis and arteriogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A model for gene therapy of human hereditary lymphedema

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Identification of two Sp1 phosphorylation sites for p42/p44 mitogen-activated protein kinases: their implication in vascular endothelial growth factor gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Reactive oxygen generated by Nox1 triggers the angiogenic switch

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Lens-specific VEGF-A expression induces angioblast migration and proliferation and stimulates angiogenic remodeling.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Targeting of both mouse neuropilin-1 and neuropilin-2 genes severely impairs developmental yolk sac and embryonic angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Exogenous clustered neuropilin 1 enhances vasculogenesis and angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Neuropilin-1 expression by tumor cells promotes tumor angiogenesis and progression

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Identification of a natural soluble neuropilin-1 that binds vascular endothelial growth factor: In vivo expression and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Arteriolar and venular patterning in retinas of mice selectively expressing VEGF isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Neuropilin-1 participates in wound angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A conserved family of prolyl-4-hydroxylases that modify HIF

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Target molecules for anti-angiogenic therapy: from basic research to clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Angiogenesis inhibitors revised and revived at AACR

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Suppression of Luteal Angiogenesis in the Primate after Neutralization of Vascular Endothelial Growth Factor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Cancer therapy. Setbacks for endostatin

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Specialization of tumour vasculature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Eradication of large solid tumors in mice with an immunotoxin directed against tumor vasculature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Targeting tumour vasculature: the development of combretastatin A4.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Genes expressed in human tumor endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

In silico cloning of novel endothelial-specific genes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Active immunization against the vascular endothelial growth factor receptor flk1 inhibits tumor angiogenesis and metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Tumor regression by targeted gene delivery to the neovasculature

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A precursor form of vascular endothelial growth factor arises by initiation from an upstream in-frame CUG codon

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Isoform-specific expression of VEGF-B in normal tissues and tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Multiple forms of mouse vascular endothelial growth factor-D are generated by RNA splicing and proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2802%2902109-0

7 January 2021

10.1016/S0165-6147(02)02109-0

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12457776