(Q35019429)

5 August 2017

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title

Molecular basis for anti-amyloid therapy in the prevention and treatment of Alzheimer's disease (English)

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5 August 2017

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Sam Gandy

1

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5 August 2017

publication date

1 November 2002

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5 August 2017

published in

Neurobiology of Aging

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5 August 2017

volume

23

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5 August 2017

issue

6

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5 August 2017

page(s)

1009-1016

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Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

5 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Neuropathological indexes of Alzheimer's disease in demented and nondemented persons aged 80 years and older

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Activated release of membrane-anchored TGF-alpha in the absence of cytosol

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide

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https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice

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https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Estrogens influence growth, maturation, and amyloid beta-peptide production in neuroblastoma cells and in a beta-APP transfected kidney 293 cell line.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Dehydroepiandrosterone augments M1-muscarinic receptor-stimulated amyloid precursor protein secretion in desensitized PC12M1 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Beta A4 deposits are constant in the brain of the oldest old: an immunocytochemical study of 20 French centenarians

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Estradiol modulates protein kinase C activity in the rat pituitary in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Chemical andropause and amyloid-beta peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Nonsteroidal Antiinflammatory Drugs and the Risk of Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

An essential role for ectodomain shedding in mammalian development

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Ovariectomy and 17beta-estradiol modulate the levels of Alzheimer's amyloid beta peptides in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E, Dementia, and Cortical Deposition of β-Amyloid Protein

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Complement activation by beta-amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Estrogen therapy in postmenopausal women: effects on cognitive function and dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

Modulation of A(beta) peptides by estrogen in mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0197-4580%2802%2900125-2

7 January 2021

10.1016/S0197-4580(02)00125-2

Identifiers

DOI

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5 August 2017

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