(Q35022919)

5 August 2017

title

Adaptation and constraint at Toll-like receptors in primates (English)

1 reference

5 August 2017

0 references

2

Michael W Nachman

1 reference

5 August 2017

Gabriela Wlasiuk

1

1 reference

5 August 2017

publication date

21 April 2010

1 reference

Molecular Biology and Evolution

5 August 2017

published in

1 reference

5 August 2017

volume

27

1 reference

5 August 2017

issue

9

1 reference

5 August 2017

page(s)

2172-2186

1 reference

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

5 August 2017

cites work

1 reference

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8 July 2018

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Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions

8 July 2018

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8 July 2018

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Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature

8 July 2018

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DnaSP v5: a software for comprehensive analysis of DNA polymorphism data

8 July 2018

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The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

8 July 2018

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A history of recurrent positive selection at the toll-like receptor 5 in primates

8 July 2018

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Protein kinase R reveals an evolutionary model for defeating viral mimicry

8 July 2018

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

8 July 2018

1 reference

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Toll-like receptor heterodimer variants protect from childhood asthma

8 July 2018

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The evolutionary history of the CD209 (DC-SIGN) family in humans and non-human primates

8 July 2018

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

8 July 2018

1 reference

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Proportionally more deleterious genetic variation in European than in African populations.

8 July 2018

1 reference

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Full-exon resequencing reveals toll-like receptor variants contribute to human susceptibility to tuberculosis disease

8 July 2018

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Inferring human population sizes, divergence times and rates of gene flow from mitochondrial, X and Y chromosome resequencing data

8 July 2018

1 reference

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Adaptive evolution of proteins secreted during sperm maturation: an analysis of the mouse epididymal transcriptome

8 July 2018

1 reference

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Toll-like receptors 7, 8, and 9: linking innate immunity to autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A common human TLR1 polymorphism regulates the innate immune response to lipopeptides

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

How important are Toll-like receptors for antimicrobial responses?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Comparative sequence analysis of leucine-rich repeats (LRRs) within vertebrate toll-like receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

PAML 4: phylogenetic analysis by maximum likelihood

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

The polymorphism P315L of human toll-like receptor 1 impairs innate immune sensing of microbial cell wall components

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

The delayed rise of present-day mammals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Predicting the effects of amino acid substitutions on protein function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Demographic history and genetic differentiation in apes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Pathogen recognition and innate immunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A map of recent positive selection in the human genome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Site-to-site variation of synonymous substitution rates

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

The evolution of vertebrate Toll-like receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Datamonkey: rapid detection of selective pressure on individual sites of codon alignments

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Not so different after all: a comparison of methods for detecting amino acid sites under selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Bayes empirical bayes inference of amino acid sites under positive selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Divergence Population Genetics of Chimpanzees

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Population history and natural selection shape patterns of genetic variation in 132 genes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Toll-like receptor signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Nucleotide diversity in gorillas

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Widespread purifying selection at polymorphic sites in human protein-coding loci

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Libsequence: a C++ class library for evolutionary genetic analysis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Low nucleotide diversity in chimpanzees and bonobos

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Larger genetic differences within africans than between Africans and Eurasians

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Excess of rare amino acid polymorphisms in the Toll-like receptor 4 in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Prediction of deleterious human alleles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A novel polymorphism in the toll-like receptor 2 gene and its potential association with staphylococcal infection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Hitchhiking under positive Darwinian selection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Codon-substitution models for heterogeneous selection pressure at amino acid sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

PAML: a program package for phylogenetic analysis by maximum likelihood

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Excess amino acid polymorphism in mitochondrial DNA: contrasts among genes from Drosophila, mice, and humans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Statistical tests of neutrality of mutations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

The age of a neutral mutant persisting in a finite population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

A test of neutral molecular evolution based on nucleotide data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Statistical method for testing the neutral mutation hypothesis by DNA polymorphism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Adaptive protein evolution at the Adh locus in Drosophila

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

On the number of segregating sites in genetical models without recombination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Mathematical model for studying genetic variation in terms of restriction endonucleases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSQ104

Natural selection in the TLR-related genes in the course of primate evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSQ104

Dynamic evolution of the innate immune system in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSQ104

Sequence variants in toll-like receptor 10 are associated with nasopharyngeal carcinoma risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSQ104

Balancing selection is the main force shaping the evolution of innate immunity genes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3107592

Toll-like Receptor 4 Polymorphisms and Atherogenesis

25 October 2018

1 reference

https://api.crossref.org/works/10.1093%2FMOLBEV%2FMSQ104

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting edge: A common polymorphism impairs cell surface trafficking and functional responses of TLR1 but protects against leprosy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20410160

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/MOLBEV/MSQ104

1 reference

5 August 2017

1 reference

5 August 2017

1 reference