(Q35024151)

5 August 2017

title

Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor (English)

1 reference

5 August 2017

David A Baker

6

0 references

author name string

Jon M Resch

1

1 reference

5 August 2017

Rebecca Albano

2

1 reference

5 August 2017

XiaoQian Liu

3

1 reference

5 August 2017

Julie Hjelmhaug

4

1 reference

5 August 2017

Doug Lobner

5

1 reference

5 August 2017

SuJean Choi

7

1 reference

5 August 2017

publication date

28 July 2014

1 reference

5 August 2017

1 reference

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.

5 August 2017

cites work

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8 July 2018

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8 July 2018

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N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: a double-blind, placebo-controlled study.

8 July 2018

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beta-N-methylamino-l-alanine induces oxidative stress and glutamate release through action on system Xc(-).

8 July 2018

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VPAC and PAC receptors: From ligands to function

8 July 2018

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The role of cystine-glutamate exchange in nicotine dependence in rats and humans

8 July 2018

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Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus

8 July 2018

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Receptor actions of synaptically released glutamate: the role of transporters on the scale from nanometers to microns

8 July 2018

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Contribution of cystine-glutamate antiporters to the psychotomimetic effects of phencyclidine

8 July 2018

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N-acetylcysteine reduces extinction responding and induces enduring reductions in cue- and heroin-induced drug-seeking

8 July 2018

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Role of PACAP and VIP in astroglial functions

8 July 2018

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Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation.

8 July 2018

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Modulation of NMDA receptors by pituitary adenylate cyclase activating peptide in CA1 neurons requires G alpha q, protein kinase C, and activation of Src.

8 July 2018

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Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking

8 July 2018

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Glutathione metabolism during aging and in Alzheimer disease

8 July 2018

1 reference

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Neurotransmitters co-existing with VIP or PACAP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid

8 July 2018

1 reference

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Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

The origin and neuronal function of in vivo nonsynaptic glutamate.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

PACAP has a neurotrophic effect on cultured basal forebrain cholinergic neurons from adult rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Expression and coupling of PACAP/VIP receptors in cortical neurons and type I astrocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuron-derived peptide regulating glial glutamate transport and metabolism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Pituitary adenylyl cyclase-activating peptide: a pivotal modulator of glutamatergic regulation of the suprachiasmatic circadian clock

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Glutamate toxicity in the lung and neuronal cells: prevention or attenuation by VIP and PACAP.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Identification of VIP/PACAP receptors on rat astrocytes using antisense oligodeoxynucleotides.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Involvement of the cystine transport system xc- in the macrophage-induced glutamate-dependent cytotoxicity to neurons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

PACAP functions as a neurotrophic factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Preparation and characterization of type 1 astrocytes cultured from adult rat cortex, cerebellum, and striatum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse

8 July 2018

1 reference

VIP neurotrophism in the central nervous system: multiple effectors and identification of a femtomolar-acting neuroprotective peptide

21 January 2018

1 reference

Distribution, molecular characterization of pituitary adenylate cyclase-activating polypeptide and its precursor encoding messenger RNA in human and rat tissues.

21 January 2018

1 reference

N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study

21 January 2018

1 reference

Functional and molecular diversity of PACAP/VIP receptors in cortical neurons and type I astrocytes.

21 January 2018

1 reference

Pituitary adenylate cyclase-activating peptide in the rat central nervous system: an immunohistochemical and in situ hybridization study

21 January 2018

1 reference

Possible involvement of a cyclic AMP-dependent mechanism in PACAP-induced proliferation and ERK activation in astrocytes

21 January 2018

1 reference

Distribution of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptors (VPAC1, VPAC2, and PAC1 receptor) in the rat brain

21 January 2018

1 reference

Reduced immunoreactivities of a vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide receptor (VPAC1 receptor) in the cerebral cortex, hippocampal region, and amygdala of aged rats

21 January 2018

1 reference

Functional upregulation of system xc- by fibroblast growth factor-2.

21 January 2018

1 reference

FGF-2 induces neuronal death through upregulation of system xc-.

21 January 2018

1 reference

Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?

21 January 2018

1 reference

VIP and PACAP in the CNS: regulators of glial energy metabolism and modulators of glutamatergic signaling

21 January 2018

1 reference

Pituitary adenylate cyclase-activating polypeptide protects astroglial cells against oxidative stress-induced apoptosis

21 January 2018

1 reference

Pituitary adenylate cyclase-activating polypeptide protects rat-cultured cortical neurons from glutamate-induced cytotoxicity

21 January 2018

1 reference

Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease

21 January 2018

1 reference

Visualising the activity of the cystine-glutamate antiporter in glial cells using antibodies to aminoadipic acid, a selectively transported substrate

21 January 2018

1 reference

Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture

21 January 2018

1 reference

Glutathione-mediated neuroprotection against methylmercury neurotoxicity in cortical culture is dependent on MRP1.

21 January 2018

1 reference

Neuroprotective action of endogenous PACAP in cultured rat cortical neurons.

21 January 2018

1 reference

Glutamate and tumor-associated epilepsy

21 January 2018

1 reference

Expression of the receptor for pituitary adenylate cyclase-activating polypeptide (PAC1-R) in reactive astrocytes

21 January 2018

1 reference

PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis

21 January 2018

1 reference

Glutamate neurotoxicity in cortical cell culture.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309754

Neuronal release of vasoactive intestinal peptide is important to astrocytic protection of neurons from glutamate toxicity

25 October 2018

1 reference

12 December 2020

Exchange of cystine and glutamate across plasma membrane of human fibroblasts

1 reference

12 December 2020

Substance P regulation of glutamate and cystine transport in human astrocytoma cells

1 reference

12 December 2020

Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture

1 reference

12 December 2020

Specific binding sites for pituitary adenylate cyclase activating polypeptide (PACAP) in rat cultured astrocytes: molecular identification and interaction with vasoactive intestinal peptide (VIP)

1 reference

12 December 2020

Extrasynaptic Glutamate Spillover in the Hippocampus: Dependence on Temperature and the Role of Active Glutamate Uptake

1 reference

12 December 2020

System x(c)- activity and astrocytes are necessary for interleukin-1 beta-mediated hypoxic neuronal injury

1 reference

12 December 2020

Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation

1 reference

12 December 2020

Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide potentiate c-fos expression induced by glutamate in cultured cortical neurons

1 reference

12 December 2020

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a regulator of astrocytes: PACAP stimulates proliferation and production of interleukin 6 (IL-6), but not nerve growth factor (NGF), in cultured rat astrocyte

1 reference

12 December 2020

PACAP and glutamate are co-stored in the retinohypothalamic tract

1 reference

12 December 2020

Maintenance of neuronal glutathione by glial cells

1 reference

12 December 2020

Identifiers

DOI

10.1002/SYN.21772

1 reference

5 August 2017

1 reference

5 August 2017

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