(Q35025023)

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Risk factors for Alzheimer's disease: role of multiple antioxidants, non-steroidal anti-inflammatory and cholinergic agents alone or in combination in prevention and treatment

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Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

Europe PubMed Central

Risk factors for Alzheimer's disease: role of multiple antioxidants, non-steroidal anti-inflammatory and cholinergic agents alone or in combination in prevention and treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Alzheimer's disease

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author name string

Kedar N Prasad

1

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

William C Cole

2

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

K Che Prasad

3

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

publication date

1 December 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Journal of the American College of Nutrition

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

506-522

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Alzheimer's disease and other dementing illnesses in a defined United States population: incidence rates and clinical features

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Multiple antioxidants in the prevention and treatment of Alzheimer disease: analysis of biologic rationale

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Multiple antioxidants in the prevention and treatment of neurodegenerative disease: analysis of biologic rationale

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Molecular basis of the neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Seminars in medicine of the Beth Israel Hospital, Boston. beta-Amyloid and the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Genetic clues to Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Brain ubiquitin is markedly elevated in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Alzheimer disease: correlation of cerebro-spinal fluid and brain ubiquitin levels

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Alzheimer's disease and rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Delayed onset of Alzheimer's disease with nonsteroidal anti-inflammatory and histamine H2 blocking drugs.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

The importance of inflammatory mechanisms in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Elevated interleukin-6 secretion levels by mononuclear cells of Alzheimer's patients.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Complement activation by beta-amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Enhanced aggregation and beta structure of amyloid beta peptide after coincubation with C1q.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Regional brain activity of free radical defense enzymes in autopsy samples from patients with Alzheimer's disease and from nondemented controls

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

On the possible role of iron-induced free radical peroxidation in neural degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Radical AGEing in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A hypothesis on the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Expression of intercellular adhesion molecule 1 (ICAM-1) in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Prostaglandins as putative neurotoxins in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Role of the proteasome in Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Proteasome inhibition in neuronal cells induces a proinflammatory response manifested by upregulation of cyclooxygenase-2, its accumulation as ubiquitin conjugates, and production of the prostaglandin PGE(2).

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Nonsteroidal anti-inflammatory drugs in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Nonsteroidal antiinflammatory drug use in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Clinical trial of indomethacin in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Oxidants, antioxidants, and the degenerative diseases of aging

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Oxidative stress, glutamate, and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Transient Formation of Superoxide Radicals in Polyunsaturated Fatty Acid-Induced Brain Swelling

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

NMDA-dependent superoxide production and neurotoxicity

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Dietary pesticides (99.99% all natural)

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Rodent carcinogens: setting priorities

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Brain Cytochrome Oxidase in Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Mitochondrial genetics: a paradigm for aging and degenerative diseases?

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Nitric oxide generators produce accumulation of chelatable zinc in hippocampal neuronal perikarya

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Accelerated accumulation of amyloid beta proteins on oxidatively damaged lipid membranes

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Amyloid peptides are toxic via a common oxidative mechanism

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Hydrogen peroxide mediates amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Vitamin E protects nerve cells from amyloid beta protein toxicity

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Plasma concentrations of vitamins A and E and carotenoids in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Expression of heme oxygenase-1 in the senescent and Alzheimer-diseased brain

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Metabolic processes in Alzheimer's disease: adenine nucleotide content and production of 14CO2 from [U-14C]glucose in vitro in human neocortex.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Increased cerebral glucose-6-phosphate dehydrogenase activity in Alzheimer's disease may reflect oxidative stress

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Free radical theory of aging

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Alzheimer skin fibroblasts show increased susceptibility to free radicals.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Free radical formation in autopsy samples of Alzheimer and control cortex

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

nNOS expression in reactive astrocytes correlates with increased cell death related DNA damage in the hippocampus and entorhinal cortex in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Decreased glutathione transferase activity in brain and ventricular fluid in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Increased susceptibility of Alzheimer's disease temporal cortex to oxygen free radical-mediated processes.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Regional membrane phospholipid alterations in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Amyloid beta peptide induces necrosis rather than apoptosis

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Potentiation of beta-folding of beta-amyloid peptide 25-35 by aluminum salts

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Inhibitors of free radical formation fail to attenuate direct beta-amyloid25-35 peptide-mediated neurotoxicity in rat hippocampal cultures.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Upregulation of amyloid precursor protein messenger RNA in response to traumatic brain injury: an ovine head impact model

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Altered expression of amyloid protein precursor mRNA in the rat hippocampus following trimethyltin intoxication: an in situ hybridization study

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Amyloid precursor protein gene isoforms in Alzheimer's disease and other neurodegenerative disorders.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Alzheimer's disease: a re-examination of the amyloid hypothesis

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Inhibition of the ubiquitin-proteasome system in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Proteasome activity is critical for the cAMP-induced differentiation of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Link between heart disease, cholesterol, and Alzheimer's disease: a review

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Statins and the risk of dementia

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

New gene tied to common form of Alzheimer's

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Genetic testing and Alzheimer disease: has the time come? Alzheimer Disease Working Group of the Stanford Program in Genomics, Ethics & Society

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Alpha-2 macroglobulin is genetically associated with Alzheimer disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A full genome scan for late onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Specific downregulation of presenilin 2 gene expression is prominent during early stages of sporadic late-onset Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Vitamin E and cancer prevention: recent advances and future potentials

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Growth factors and vitamin E modify neuronal glutamate toxicity

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Vitamin E attenuates the toxic effects of 6-hydroxydopamine on free radical scavenging systems in rat brain

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Antioxidant functions of carotenoids

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Beta-carotene induces morphological differentiation and decreases adenylate cyclase activity in melanoma cells in culture

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Inhibition of adriamycin-promoted microsomal lipid peroxidation by beta-carotene, alpha-tocopherol and retinol at high and low oxygen partial pressures

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Vitamin E: interactions with free radicals and ascorbate

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

The systemic availability of oral glutathione

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Mechanisms and dynamics of antioxidant action of ubiquinol

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Vitamin B12-induced reduction of platelet monoamine oxidase activity in patients with dementia and pernicious anaemia

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's Disease Cooperative Study.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Cyclo-oxygenase-2 inhibitors: rationale and therapeutic potential for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Nonsteroidal anti-inflammatory drug use and Alzheimer-type pathology in aging

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Synergistic inhibition of cyclooxygenase-2 expression by vitamin E and aspirin

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Do nonsteroidal anti-inflammatory drugs decrease the risk for Alzheimer's disease?: The Rotterdam Study

1 reference

https://api.crossref.org/works/10.1080%2F07315724.2002.10719249

21 January 2018

Identifiers

10.1080/07315724.2002.10719249

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

release_eismurdktjbgzlmrcixki2yoi4

1 reference

https://api.fatcat.wiki/v0/release/eismurdktjbgzlmrcixki2yoi4

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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