(Q35032502)

25409153

5 August 2017

title

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide (English)

1 reference

5 August 2017

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Samuel H. Wilson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

6

Tamar Schlick

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Bret D Freudenthal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

William A Beard

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

David D Shock

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Taejin Kim

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

17 November 2014

1 reference

5 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

7536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

635-639

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nature13886

9 June 2020

exact match

0 references

cites work

All-atom empirical potential for molecular modeling and dynamics studies of proteins

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Structure and mechanism of DNA polymerase β

8 July 2018

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

8 July 2018

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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

8 July 2018

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Crystal Structure of DNA Polymerase β with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position

8 July 2018

1 reference

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Structural Basis for Promutagenicity of 8-Halogenated Guanine

8 July 2018

1 reference

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Observing a DNA Polymerase Choose Right from Wrong

8 July 2018

1 reference

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DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion

8 July 2018

1 reference

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Watching DNA polymerase η make a phosphodiester bond

8 July 2018

1 reference

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Human POLB gene is mutated in high percentage of colorectal tumors

8 July 2018

1 reference

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Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics

8 July 2018

1 reference

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Oxidative stress, inflammation, and cancer: how are they linked?

8 July 2018

1 reference

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Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site

8 July 2018

1 reference

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

8 July 2018

1 reference

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Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions

8 July 2018

1 reference

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Aprataxin, poly-ADP ribose polymerase 1 (PARP-1) and apurinic endonuclease 1 (APE1) function together to protect the genome against oxidative damage.

8 July 2018

1 reference

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Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.

8 July 2018

1 reference

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Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides

8 July 2018

1 reference

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Magnesium-induced assembly of a complete DNA polymerase catalytic complex.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Scalable molecular dynamics with NAMD

8 July 2018

1 reference

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Coot: model-building tools for molecular graphics

8 July 2018

1 reference

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Endogenous DNA damage in humans: a review of quantitative data

8 July 2018

1 reference

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Structural Insights into the Origins of DNA Polymerase Fidelity

8 July 2018

1 reference

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8-oxodGTP incorporation by DNA polymerase beta is modified by active-site residue Asn279.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Purification and domain-mapping of mammalian DNA polymerase beta.

8 July 2018

1 reference

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DNA precursor pool: a significant target for N-methyl-N-nitrosourea in C3H/10T1/2 clone 8 cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

NMR studies of a DNA containing 8-hydroxydeoxyguanosine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

8 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4312183

8 July 2018

https://api.crossref.org/works/10.1038%2FNATURE13886

inferred from DOI database lookup

7 January 2021

based on heuristic

The mammalian mismatch repair pathway removes DNA 8-oxodGMP incorporated from the oxidized dNTP pool

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

DNA polymerase beta fidelity: halomethylene-modified leaving groups in pre-steady-state kinetic analysis reveal differences at the chemical transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Influence of DNA structure on DNA polymerase beta active site function: extension of mutagenic DNA intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Loss of DNA polymerase beta stacking interactions with templating purines, but not pyrimidines, alters catalytic efficiency and fidelity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Atomic charges derived from electrostatic potentials: A detailed study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Subtle but variable conformational rearrangements in the replication cycle of Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) may accommodate lesion bypass

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13886

Single-turnover kinetic analysis of the mutagenic potential of 8-oxo-7,8-dihydro-2'-deoxyguanosine during gap-filling synthesis catalyzed by human DNA polymerases lambda and beta

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25409153

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13886

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

journals/nature/FreudenthalBPSK15

9 June 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

25409153

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409153%20AND%20SRC:MED&resulttype=core&format=json