(Q27643976)

57

0 references

Pål Stenmark

54

0 references

Ann-Sofie Jemth

3

0 references

Fabienne Z Gaugaz

Fabienne Z Gaugaz

32

0 references

Berglind O Einarsdottir

Berglind Osk Einarsdottir

10

0 references

Robert Gustafsson

Robert Gustafsson

16

0 references

Hanna Axelsson

Hanna Axelsson

42

0 references

Helge Gad

Helge Gad

1

0 references

Olov A Wallner

Olov A Wallner

37

0 references

Ronnie Berntsson

Ronnie P-A Berntsson

15

0 references

Matthieu Desroses

Matthieu Desroses

20

0 references

Roger Olofsson Bagge

Roger Olofsson

22

0 references

Mikael Altun

Mikael Altun

31

0 references

Thomas Lundbäck

Thomas Lundbäck

9

0 references

Christina Kalderén

Christina Kalderén

41

0 references

Martin Scobie

Martin Scobie

55

0 references

Anna-Lena Gustavsson

Anna-Lena Gustavsson

21

0 references

Ulrika Warpman Berglund

Ulrika Warpman Berglund

56

0 references

Tobias Koolmeister

2

Tobias Koolmeister

0 references

Saeed Eshtad

4

Saeed Eshtad

0 references

Linda Elfsmark

7

Linda M Svensson

0 references

Aljona Saleh

11

Aljona Saleh

0 references

Camilla Göktürk

12

Camilla Göktürk

0 references

Pawel Baranczewski

13

Pawel Baranczewski

0 references

Richard Svensson

14

Richard Svensson

0 references

Kia Strömberg

17

Marie-Caroline Jacques-Cordonnier

Kia Strömberg

0 references

19

Marie-Caroline Jacques-Cordonnier

0 references

Evert J Homan

24

Evert J Homan

0 references

Lars Bräutigam

26

Lars Bräutigam

0 references

Andreas Höglund

28

Andreas Höglund

0 references

Anna Hagenkort

29

Anna Hagenkort

0 references

Therese Pham

30

Therese Pham

0 references

Svante Vikingsson

33

Svante Vikingsson

0 references

Bastiaan Evers

34

Bastiaan Evers

0 references

Martin Henriksson

35

Martin Henriksson

0 references

Lars G. J. Hammarström

38

Lars G J Hammarström

0 references

Elisee Wiita

39

Elisee Wiita

0 references

Ingrid Almlöf

40

Ingrid Almlöf

0 references

Tatjana Djureinovic

43

Tatjana Djureinovic

0 references

Jordi Carreras-Puigvert

44

Jordi Carreras Puigvert

0 references

Maria Häggblad

45

Maria Häggblad

0 references

Fredrik Jeppsson

46

Fredrik Jeppsson

0 references

Ulf Martens

47

Ulf Martens

0 references

Cecilia Lundin

48

Cecilia Lundin

0 references

Ingrid Granelli

50

Ingrid Granelli

0 references

Annika Jenmalm-Jensen

51

Annika Jenmalm Jensen

0 references

Per Artursson

52

Per Artursson

0 references

author name string

Sylvain A Jacques

5

0 references

Cecilia E Ström

6

0 references

Niklas Schultz

8

0 references

Kumar Sanjiv

18

0 references

Fredrik Johansson

23

0 references

Olga Loseva

25

0 references

Lars Johansson

27

0 references

Karl S A Vallin

36

0 references

Bo Lundgren

49

0 references

Jonas A Nilsson

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

53

0 references

language of work or name

English

0 references

publication date

10 April 2014

0 references

published in

Nature

0 references

volume

508

0 references

issue

7495

0 references

page(s)

215-21

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Signatures of mutational processes in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Redox control of the survival of healthy and diseased cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Redox regulation of DNA repair: implications for human health and cancer therapeutic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

DNA precursor pool: a significant target for N-methyl-N-nitrosourea in C3H/10T1/2 clone 8 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Analysis of MTH1 gene function in mice with targeted mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Activation of cellular signaling by 8-oxoguanine DNA glycosylase-1-initiated DNA base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Creation of human tumour cells with defined genetic elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Substrate ambiguity among the nudix hydrolases: biologically significant, evolutionary remnant, or both?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Contribution of hMTH1 to the maintenance of 8-oxoguanine levels in lung DNA of non-small-cell lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

ATM activation by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Defects in homologous recombination repair in mismatch-repair-deficient tumour cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Inducible and reversible gene silencing by stable integration of an shRNA-encoding lentivirus in transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Direct detection of 8-oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Protein carbonyl groups as biomarkers of oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Coot: model-building tools for molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Validation of a rapid equilibrium dialysis approach for the measurement of plasma protein binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13181

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

21 January 2018

1 reference

12 December 2020

Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption

1 reference

12 December 2020

Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis

1 reference

12 December 2020

Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13181

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

389780

1048862142

0 references

Fatcat ID

release_p3udart6drgbdhjeej3gn3vkga

0 references

389780

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference