(Q44518086)

3 December 2017

title

Substrate ambiguity among the nudix hydrolases: biologically significant, evolutionary remnant, or both? (English)

1 reference

3 December 2017

Alexander G McLennan

1

1 reference

3 December 2017

language of work or name

1 reference

27 November 2012

1 reference

Cellular and Molecular Life Sciences

3 December 2017

published in

1 reference

3 December 2017

volume

70

1 reference

3 December 2017

issue

3

1 reference

3 December 2017

page(s)

373-385

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-012-1210-3

3 December 2017

exact match

0 references

cites work

Enzyme promiscuity: mechanism and applications.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Enzyme promiscuity: evolutionary and mechanistic aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Enzyme promiscuity: a mechanistic and evolutionary perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Catalytic promiscuity and the evolution of new enzymatic activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Directed evolution of the promiscuous esterase activity of carbonic anhydrase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Enzymes with extra talents: moonlighting functions and catalytic promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Enzyme recruitment in evolution of new function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Nudix hydrolase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structures and mechanisms of Nudix hydrolases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Characterization of a nudix hydrolase from Deinococcus radiodurans with a marked specificity for (deoxy)ribonucleoside 5'-diphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Dual hydrolysis of diphosphate and triphosphate derivatives of oxidized deoxyadenosine by Orf17 (NtpA), a MutT-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Gene ytkD of Bacillus subtilis encodes an atypical nucleoside triphosphatase member of the Nudix hydrolase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A genetic screen for the identification of thiamin metabolic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A nudix enzyme removes pyrophosphate from dihydroneopterin triphosphate in the folate synthesis pathway of bacteria and plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structure and function of the E. coli dihydroneopterin triphosphate pyrophosphatase: a Nudix enzyme involved in folate biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Crystal structure of the 25 kDa subunit of human cleavage factor Im

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A highly conserved sequence motif defining the family of MutT-related proteins from eubacteria, eukaryotes and viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Molecular mechanism of the Thermus thermophilus ADP-ribose pyrophosphatase from mutational and kinetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structural and Dynamic Features of the MutT Protein in the Recognition of Nucleotides with the Mutagenic 8-Oxoguanine Base

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mutational, NMR, and NH exchange studies of the tight and selective binding of 8-oxo-dGMP by the MutT pyrophosphohydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Molecular actions of Escherichia coli MutT for control of spontaneous mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Counteraction by MutT protein of transcriptional errors caused by oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Increased A:T-->C:G mutations in the mutT strain upon 8-hydroxy-dGTP treatment: direct evidence for MutT involvement in the prevention of mutations by oxidized dGTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mutagenicity of oxidized DNA precursors in living cells: Roles of nucleotide pool sanitization and DNA repair enzymes, and translesion synthesis DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Assessing the metabolic function of the MutT 8-oxodeoxyguanosine triphosphatase in Escherichia coli by nucleotide pool analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The mutT defect does not elevate chromosomal fragmentation in Escherichia coli because of the surprisingly low levels of MutM/MutY-recognized DNA modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Effects of overexpression and antisense RNA expression of Orf17, a MutT-type enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Experimental Determination and System Level Analysis of Essential Genes in Escherichia coli MG1655

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Folate synthesis: an old enzyme identified.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The oxidized pyrimidine ribonucleotide, 5-hydroxy-CTP, is hydrolyzed efficiently by the Escherichia coli recombinant Orf135 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Amino acid residues involved in substrate recognition of the Escherichia coli Orf135 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Orf135 from Escherichia coli Is a Nudix hydrolase specific for CTP, dCTP, and 5-methyl-dCTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The ytkD (mutTA) gene of Bacillus subtilis encodes a functional antimutator 8-Oxo-(dGTP/GTP)ase and is under dual control of sigma A and sigma F RNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

An RNA pyrophosphohydrolase triggers 5'-exonucleolytic degradation of mRNA in Bacillus subtilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Human MTH1 protein hydrolyzes the oxidized ribonucleotide, 2-hydroxy-ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Programmed cell death triggered by nucleotide pool damage and its prevention by MutT homolog-1 (MTH1) with oxidized purine nucleoside triphosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Oxidized purine nucleotides, genome instability and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Analysis of MTH1 gene function in mice with targeted mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Human Mut T Homolog 1 (MTH1): a roadblock for the tumor-suppressive effects of oncogenic RAS-induced ROS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Escherichia coli lacZ reversion mutagenicity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mouse MTH2 protein which prevents mutations caused by 8-oxoguanine nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Human MTH3 (NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosphates: comparison with MTH1 and MTH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

NDX-1 protein hydrolyzes 8-oxo-7, 8-dihydrodeoxyguanosine-5'-diphosphate to sanitize oxidized nucleotides and prevent oxidative stress in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning and characterization of a new member of the Nudix hydrolases from human and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning, expression and characterization of YSA1H, a human adenosine 5′-diphosphosugar pyrophosphatase possessing a MutT motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Human placenta hydrolases active on free ADP-ribose: an ADP-sugar pyrophosphatase and a specific ADP-ribose pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Studies on the ADP-ribose pyrophosphatase subfamily of the nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning, expression and characterization of a Nudix hydrolase that catalyzes the hydrolytic breakdown of ADP-glucose linked to starch biosynthesis in Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Plastidial localization of a potato 'Nudix' hydrolase of ADP-glucose linked to starch biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Hydrolase regulates NAD+ metabolites and modulates cellular redox

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Poly(ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mammalian enzymes for preventing transcriptional errors caused by oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Caenorhabditis elegans NDX-4 is a MutT-type enzyme that contributes to genomic stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Diverse substrate recognition and hydrolysis mechanisms of human NUDT5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Identification and characterization of the Nudix hydrolase from the Archaeon, Methanococcus jannaschii, as a highly specific ADP-ribose pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Specific and nonspecific enzymes involved in the catabolism of mononucleoside and dinucleoside polyphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Analysis of the catalytic and binding residues of the diadenosine tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning, characterisation and crystallisation of a diadenosine 5',5"'-P(1),P(4)-tetraphosphate pyrophosphohydrolase from Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The crystal structure of diadenosine tetraphosphate hydrolase from Caenorhabditis elegans in free and binary complex forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Dinucleoside polyphosphates-friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Diadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Nonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcepsilonRI-activated mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A novel Nudix hydrolase for oxidized purine nucleoside triphosphates encoded by ORFYLR151c (PCD1 gene) in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Saccharomyces cerevisiae PCD1 gene encodes a peroxisomal nudix hydrolase active toward coenzyme A and its derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

FGF-2 antisense RNA encodes a nuclear protein with MutT-like antimutator activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structure and activity analyses of Escherichia coli K-12 NagD provide insight into the evolution of biochemical function in the haloalkanoic acid dehalogenase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Identification of Bdellovibrio bacteriovorus HD100 Bd0714 as a Nudix dGTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structure of a Nudix hydrolase (MutT) in the Mg 2+ -bound state from Bartonella henselae , the bacterium responsible for cat scratch fever

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

UV hyper-resistance in Prochlorococcus MED4 results from a single base pair deletion just upstream of an operon encoding nudix hydrolase and photolyase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

CiMutT, an asidian MutT homologue, has a 7, 8-dihydro-8-oxo-dGTP pyrophosphohydrolase activity responsible for sanitization of oxidized nucleotides in Ciona intestinalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Genome-scale phylogenetic function annotation of large and diverse protein families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Interactions among the Escherichia coli mutT, mutM, and mutY damage prevention pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Structure and Biological Function of the RNA Pyrophosphohydrolase BdRppH from Bdellovibrio bacteriovorus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Rickettsia prowazekii invasion gene homolog (invA) encodes a Nudix hydrolase active on adenosine (5')-pentaphospho-(5')-adenosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases is essential for the ability of Salmonella enterica serovar typhimurium to invade cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The pnhA gene of Pasteurella multocida encodes a dinucleoside oligophosphate pyrophosphatase member of the Nudix hydrolase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Legionella pneumophila NudA Is a Nudix hydrolase and virulence factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The bacterial enzyme RppH triggers messenger RNA degradation by 5' pyrophosphate removal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Interaction network containing conserved and essential protein complexes in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The gene for Escherichia coli diadenosine tetraphosphatase is located immediately clockwise to folA and forms an operon with ksgA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A map of the interactome network of the metazoan C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Nucleus-localized antisense small RNAs with 5'-polyphosphate termini regulate long term transcriptional gene silencing in Entamoeba histolytica G3 strain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

LC/MS analysis of cellular RNA reveals NAD-linked RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A chemical screen for biological small molecule-RNA conjugates reveals CoA-linked RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Tri- to be mono- for bacterial mRNA decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Xenopus U8 snoRNA binding protein is a conserved nuclear decapping enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Evolutionary conservation supports ancient origin for Nudt16, a nuclear-localized, RNA-binding, RNA-decapping enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Metal determines efficiency and substrate specificity of the nuclear NUDIX decapping proteins X29 and H29K (Nudt16)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Multiple mRNA decapping enzymes in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

mRNA decay enzymes: decappers conserved between yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Functional characterization of the mammalian mRNA decapping enzyme hDcp2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Transcript-specific decapping and regulated stability by the human Dcp2 decapping protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The African swine fever virus g5R protein possesses mRNA decapping activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The g5R (D250) gene of African swine fever virus encodes a Nudix hydrolase that preferentially degrades diphosphoinositol polyphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Inositol pyrophosphates: structure, enzymology and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Are inositol pyrophosphates signalling molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Diphosphoinositol polyphosphates: metabolic messengers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Diphosphoinositol polyphosphates: what are the mechanisms?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Nudix Hydrolase CDP-Chase, a CDP-Choline Pyrophosphatase, Is an Asymmetric Dimer with Two Distinct Enzymatic Activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Schizosaccharomyces pombe Aps1, a diadenosine 5',5' "-P1, P6-hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: cloning of the gene and characterization of the purified enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Oxidation of the diphosphoinositol polyphosphate phosphohydrolase-like Nudix hydrolase Aps from Drosophila melanogaster induces thermolability--A possible regulatory switch?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Kinetic, dynamic, ligand binding properties, and structural models of a dual-substrate specific nudix hydrolase from Schizosaccharomyces pombe.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Inositol pyrophosphate pyrotechnics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Identification of an evolutionarily conserved family of inorganic polyphosphate endopolyphosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Cloning and characterization of the first member of the Nudix family from Arabidopsis thaliana.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Lowered nudix type 5 (NUDT5) expression leads to cell cycle retardation in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

A comparative analysis of the molecular characteristics of the Arabidopsis CoA pyrophosphohydrolases AtNUDX11, 15, and 15a

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Decapitation: poxvirus makes RNA lose its head

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1210-3

Alternate endings: a new story for mRNA decapping

21 January 2018

1 reference

12 December 2020

MutY repair is mutagenic in mutT- strains of Escherichia coli

1 reference

12 December 2020

Effects of 8-hydroxy-GTP and 2-hydroxy-ATP on in vitro transcription

1 reference

12 December 2020

The gene ygdP, associated with the invasiveness of Escherichia coli K1, designates a Nudix hydrolase, Orf176, active on adenosine (5')-pentaphospho-(5')-adenosine (Ap5A).

1 reference

12 December 2020

The IalA invasion gene of Bartonella bacilliformis encodes a (de)nucleoside polyphosphate hydrolase of the MutT motif family and has homologs in other invasive bacteria

1 reference

12 December 2020

The role of the mutT gene of Escherichia coli in maintaining replication fidelity

1 reference

12 December 2020

The plant Nudix hydrolase family.

1 reference

12 December 2020

Evolutionary loss of 8-oxo-G repair components among eukaryotes

1 reference

12 December 2020

A diadenosine 5',5''-P1P4 tetraphosphate (Ap4A) hydrolase from Arabidopsis thaliana that is activated preferentially by Mn2+ ions

1 reference

12 December 2020

Cloning, expression and characterization of YSA1H, a human adenosine 5'-diphosphosugar pyrophosphatase possessing a MutT motif

1 reference

12 December 2020

Conformational diversity and protein evolution--a 60-year-old hypothesis revisited

1 reference

12 December 2020

Suppression of spontaneous and hydrogen peroxide-induced mutations by a MutT-type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 protein

1 reference

12 December 2020

10.1007/S00018-012-1210-3

Identifiers

DOI

1 reference

3 December 2017

1 reference