(Q37588509)

21 August 2017

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title

Inositol pyrophosphates: structure, enzymology and function (English)

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21 August 2017

4

Per-Olof Berggren

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21 August 2017

author name string

Christopher John Barker

series ordinal

1

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21 August 2017

Christopher Illies

series ordinal

2

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21 August 2017

Gian Carlo Gaboardi

series ordinal

3

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21 August 2017

publication date

28 August 2009

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Cellular and Molecular Life Sciences

21 August 2017

published in

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21 August 2017

volume

66

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21 August 2017

issue

24

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21 August 2017

page(s)

3851-3871

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The inositol phosphates in WRK1 rat mammary tumour cells

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Diphospho-myo-inositol phosphates from Dictyostelium identified as D-6-diphospho-myo-inositol pentakisphosphate and D-5,6-bisdiphospho-myo-inositol tetrakisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Molecular cloning and expression of a rat hepatic multiple inositol polyphosphate phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Turnover of inositol pentakisphosphates, inositol hexakisphosphate and diphosphoinositol polyphosphates in primary cultured hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

The g5R (D250) gene of African swine fever virus encodes a Nudix hydrolase that preferentially degrades diphosphoinositol polyphosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

The interaction of coatomer with inositol polyphosphates is conserved in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Invited review: Effects of heat and cold stress on mammalian gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-009-0115-2

Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

21 January 2018

1 reference

12 December 2020

Schizosaccharomyces pombe Aps1, a diadenosine 5',5' "-P1, P6-hexaphosphate hydrolase that is a member of the nudix (MutT) family of hydrolases: cloning of the gene and characterization of the purified enzyme

1 reference

12 December 2020

The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

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12 December 2020

Inositol pyrophosphates: metabolism and signaling

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12 December 2020

Characterization of the InsP6-dependent interaction between CK2 and Nopp140.

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12 December 2020

Complex changes in cellular inositol phosphate complement accompany transit through the cell cycle

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12 December 2020

Gene deletion of inositol hexakisphosphate kinase 1 reveals inositol pyrophosphate regulation of insulin secretion, growth, and spermiogenesis

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12 December 2020

Genetic interaction between ribosome biogenesis and inositol polyphosphate metabolism in Saccharomyces cerevisiae

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12 December 2020

Casein kinase 2: an 'eminence grise' in cellular regulation?

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12 December 2020

Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2

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12 December 2020

Telomeres shorten during ageing of human fibroblasts

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12 December 2020

Diphospho-myo-inositol phosphates in Dictyostelium and Polysphondylium: identification of a new bisdiphospho-myo-inositol tetrakisphosphate

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12 December 2020

Molecular definition of a novel inositol polyphosphate metabolic pathway initiated by inositol 1,4,5-trisphosphate 3-kinase activity in Saccharomyces cerevisiae

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12 December 2020

Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress

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12 December 2020

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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12 December 2020

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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12 December 2020

Phosphoinositides as regulators of membrane trafficking in health and disease.

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12 December 2020

Golgi coatomer binds, and forms K(+)-selective channels gated by, inositol polyphosphates.

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12 December 2020

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

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12 December 2020

Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state.

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12 December 2020

Signal transduction during environmental stress: InsP8 operates within highly restricted contexts

1 reference

12 December 2020

Proprotein convertases: lessons from knockouts

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12 December 2020

Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited

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12 December 2020

Towards a proteome-scale map of the human protein–protein interaction network

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12 December 2020

Identification and characterization of a novel inositol hexakisphosphate kinase

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12 December 2020

PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase

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12 December 2020

A novel context for the 'MutT' module, a guardian of cell integrity, in a diphosphoinositol polyphosphate phosphohydrolase

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12 December 2020

The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrolase. Overlapping substrate specificities in a MutT-type protein

1 reference

12 December 2020

HSP90 and the chaperoning of cancer

1 reference

12 December 2020

Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy

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12 December 2020

Inositol trisphosphate and calcium oscillations

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12 December 2020

Structural analysis of the carboxy terminal PH domain of pleckstrin bound to D-myo-inositol 1,2,3,5,6-pentakisphosphate

1 reference

12 December 2020

Telomere maintenance by intracellular signals: new kid on the block?

1 reference

12 December 2020

Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein.

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12 December 2020

HSP90 regulates cell survival via inositol hexakisphosphate kinase-2.

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12 December 2020

Osmotic stress-induced remodeling of the cortical cytoskeleton

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12 December 2020

Inositol polyphosphates: a new frontier for regulating gene expression

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12 December 2020

Phosphatidylinositol phosphate kinase: a link between protein kinase and glutathione synthase folds

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12 December 2020

Numbering of atoms in myo-inositol. Recommendations 1988. Nomenclature Committee of the International Union of Biochemistry

1 reference

12 December 2020

Apo2L/TRAIL induction and nuclear translocation of inositol hexakisphosphate kinase 2 during IFN-beta-induced apoptosis in ovarian carcinoma.

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12 December 2020

14-3-3 proteins: a historic overview

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12 December 2020

Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases

1 reference

12 December 2020

Protein kinase CK2 in gene control at cell cycle entry

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12 December 2020

The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups

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12 December 2020

Diadenosine polyphosphates: Their biological and pharmacological significance

1 reference

12 December 2020

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

1 reference

12 December 2020

Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate

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12 December 2020

Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells

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12 December 2020

Requirement of inositol pyrophosphates for full exocytotic capacity in pancreatic beta cells

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12 December 2020

Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

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12 December 2020

The interconversion of inositol 1,3,4,5,6-pentakisphosphate and inositol tetrakisphosphates in AR4-2J cells

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12 December 2020

Regulation of a cyclin-CDK-CDK inhibitor complex by inositol pyrophosphates

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12 December 2020

Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis

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12 December 2020

Synthesis of InsP7 by the Inositol Hexakisphosphate Kinase 1 (IP6K1).

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12 December 2020

Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas

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12 December 2020

Inositol hexakisphosphate kinase products contain diphosphate and triphosphate groups

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12 December 2020

Purified inositol hexakisphosphate kinase is an ATP synthase: diphosphoinositol pentakisphosphate as a high-energy phosphate donor

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12 December 2020

Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases

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12 December 2020

Protein kinase CK2 is inhibited by human nucleolar phosphoprotein p140 in an inositol hexakisphosphate-dependent manner.

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12 December 2020

Specific interaction of Golgi coatomer protein alpha-COP with phosphatidylinositol 3,4,5-trisphosphate

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12 December 2020

Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

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12 December 2020

Inhibition of Phosphatases and Increased Ca2+ Channel Activity by Inositol Hexakisphosphate

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12 December 2020

The heat shock protein 90 chaperone complex: an evolving therapeutic target.

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12 December 2020

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

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12 December 2020

Immunocytochemical localization of prohormone convertase 1/3 and 2 in pancreatic islet cells and islet cell tumors

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12 December 2020

Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions

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12 December 2020

In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis

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12 December 2020

The exosome and RNA quality control in the nucleus

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12 December 2020

The life of a cell: apoptosis regulation by the PI3K/PKB pathway

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12 December 2020

Interaction of nucleolin with an evolutionarily conserved pre-ribosomal RNA sequence is required for the assembly of the primary processing complex

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12 December 2020

A conserved family of enzymes that phosphorylate inositol hexakisphosphate

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12 December 2020

Inositol pyrophosphates are required for DNA hyperrecombination in protein kinase c1 mutant yeast

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12 December 2020

Phosphorylation of proteins by inositol pyrophosphates

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12 December 2020

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

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12 December 2020

Inositol hexakisphosphate binds to clathrin assembly protein 3 (AP-3/AP180) and inhibits clathrin cage assembly in vitro

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12 December 2020

Accumulation of [3H]-inositol into inositol polyphosphates during development of Dictyostelium

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12 December 2020

Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

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12 December 2020

Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases

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12 December 2020

An unusual member of the Cdk family: Cdk5.

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12 December 2020

A quantitative atlas of mitotic phosphorylation

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12 December 2020

The Saccharomyces cerevisiae YOR163w gene encodes a diadenosine 5', 5"'-P1,P6-hexaphosphate (Ap6A) hydrolase member of the MutT motif (Nudix hydrolase) family

1 reference

12 December 2020

How versatile are inositol phosphate kinases?

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12 December 2020

Cyclin-dependent kinase 5 promotes insulin exocytosis.

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12 December 2020

Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate

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12 December 2020

Dinucleoside polyphosphates-friend or foe?

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12 December 2020

Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma

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12 December 2020

The transcriptional regulator, Arg82, is a hybrid kinase with both monophosphoinositol and diphosphoinositol polyphosphate synthase activity

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12 December 2020

Mutant ras gene induces elevated levels of inositol tris- and hexakisphosphates in Dictyostelium

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12 December 2020

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases

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12 December 2020

Hepatic Ins(1,3,4,5)P4 3-phosphatase is compartmentalized inside endoplasmic reticulum

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12 December 2020

Oncogenic transformation by beta-catenin: deletion analysis and characterization of selected target genes

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12 December 2020

Comparison of the rat nucleolar protein nopp140 with its yeast homolog SRP40. Differential phosphorylation in vertebrates and yeast.

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12 December 2020

Detection of an appropriate kinase activity in branchial arches I and II that coincides with peak expression of the Treacher Collins syndrome gene product, treacle

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12 December 2020

Identification and purification of diphosphoinositol pentakisphosphate kinase, which synthesizes the inositol pyrophosphate bis(diphospho)inositol tetrakisphosphate

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12 December 2020

Synthesis and metabolism of bis-diphosphoinositol tetrakisphosphate in vitro and in vivo

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12 December 2020

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

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12 December 2020

Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death

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12 December 2020

Inositol diphosphate signaling regulates telomere length

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12 December 2020

Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function

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12 December 2020

The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis

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12 December 2020

Phospholipid scramblases: an overview

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12 December 2020

Characterization of a selective inhibitor of inositol hexakisphosphate kinases: use in defining biological roles and metabolic relationships of inositol pyrophosphates.

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12 December 2020

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway

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12 December 2020

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate

1 reference

12 December 2020

Phosphorylation of nucleolin by a nucleolar type NII protein kinase

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12 December 2020

Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein

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12 December 2020

Protein pyrophosphorylation by inositol pyrophosphates is a posttranslational event

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12 December 2020

Identification of a cDNA/protein leading to an increased Pi-uptake in Xenopus laevis oocytes.

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12 December 2020

Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP-2.

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12 December 2020

neo-inositol polyphosphates in the amoeba Entamoeba histolytica

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12 December 2020

Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2

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12 December 2020

Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation

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12 December 2020

Inhibition of clathrin assembly by high affinity binding of specific inositol polyphosphates to the synapse-specific clathrin assembly protein AP-3.

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12 December 2020

Inositol derivatives: evolution and functions

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12 December 2020

Roles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biology

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12 December 2020

Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand

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12 December 2020

Nopp 140 shuttles on tracks between nucleolus and cytoplasm

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12 December 2020

Inositol pyrophosphates regulate endocytic trafficking

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12 December 2020

The nucleolus exhibits an osmotically regulated gatekeeping activity that controls the spatial dynamics and functions of nucleolin

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12 December 2020

Understanding the biological significance of diphosphoinositol polyphosphates ('inositol pyrophosphates').

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12 December 2020

Inositol pyrophosphates get the vip1 treatment

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12 December 2020

Inositol lipids and phosphates in erythrocytes and HL60 cells

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12 December 2020

An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

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12 December 2020

GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase

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12 December 2020

Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases. An expanding Nudt family

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12 December 2020

Determination of free and bound manganese(II) in hepatocytes from fed and fasted rats

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12 December 2020

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

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12 December 2020

Site-directed mutagenesis of diphosphoinositol polyphosphate phosphohydrolase, a dual specificity NUDT enzyme that attacks diadenosine polyphosphates and diphosphoinositol polyphosphates

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12 December 2020

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

1 reference

12 December 2020

PI3K pathway alterations in cancer: variations on a theme

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12 December 2020

Disruption and overexpression of the Schizosaccharomyces pombe aps1 gene, and effects on growth rate, morphology and intracellular diadenosine 5',5"'-P1,P5-pentaphosphate and diphosphoinositol polyphosphate concentrations

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12 December 2020

Inhibitors of the HSP90 molecular chaperone: current status

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12 December 2020

The detection, purification, structural characterization, and metabolism of diphosphoinositol pentakisphosphate(s) and bisdiphosphoinositol tetrakisphosphate(s)

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12 December 2020

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases

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12 December 2020

Inositide evolution - towards turtle domination?

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12 December 2020

The coiled coil region (amino acids 129-250) of the tumor suppressor protein adenomatous polyposis coli (APC). Its structure and its interaction with chromosome maintenance region 1 (Crm-1)

1 reference

12 December 2020

Turnover of inositol polyphosphate pyrophosphates in pancreatoma cells

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12 December 2020

Human Gene and Protein Database (HGPD): a novel database presenting a large quantity of experiment-based results in human proteomics

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12 December 2020

Regulation of intestinal Na+-dependent phosphate co-transporters by a low-phosphate diet and 1,25-dihydroxyvitamin D3

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12 December 2020

Signaling by higher inositol polyphosphates. Synthesis of bisdiphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress

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12 December 2020

10.1007/S00018-009-0115-2

Identifiers

DOI

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21 August 2017

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