(Q35035283)

English

Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Role of microRNA 1207-5P and its host gene, the long non-coding RNA Pvt1, as mediators of extracellular matrix accumulation in the kidney: implications for diabetic nephropathy (English)

1 reference

Europe PubMed Central

5 August 2017

extracellular matrix

0 references

0 references

1 reference

based on heuristic

inferred from title

diabetic nephropathy

1 reference

based on heuristic

inferred from title

author name string

M Lucrecia Alvarez

1

1 reference

Europe PubMed Central

5 August 2017

Mahdieh Khosroheidari

2

1 reference

Europe PubMed Central

5 August 2017

Elena Eddy

3

1 reference

Europe PubMed Central

5 August 2017

Jeff Kiefer

4

1 reference

Europe PubMed Central

5 August 2017

language of work or name

0 references

publication date

25 October 2013

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

8

1 reference

Europe PubMed Central

5 August 2017

10

1 reference

Europe PubMed Central

5 August 2017

e77468

1 reference

Europe PubMed Central

5 August 2017

copyright license

Creative Commons Attribution 4.0 International

25 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808414

8 July 2018

Transforming growth factor-β-induced cross talk between p53 and a microRNA in the pathogenesis of diabetic nephropathy

1 reference

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8 July 2018

Towards microRNA-based therapeutics for diabetic nephropathy

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8 July 2018

The role of non-coding RNAs in diabetic nephropathy: potential applications as biomarkers for disease development and progression

1 reference

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8 July 2018

Enemy or partner: relationship between intronic micrornas and their host genes

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8 July 2018

Long noncoding RNA: its physiological and pathological roles

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Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs

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MicroRNAs and the glomerulus

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A miR-1207-5p binding site polymorphism abolishes regulation of HBEGF and is associated with disease severity in CFHR5 nephropathy

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Towards understanding the inherited susceptibility for nephropathy in diabetes

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p53-Dependent induction of PVT1 and miR-1204.

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Epigenetics in diabetic kidney disease

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A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA

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TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

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Functional characterization of the plasmacytoma variant translocation 1 gene (PVT1) in diabetic nephropathy

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8 July 2018

Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

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Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

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TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling

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8 July 2018

Structure and activity of putative intronic miRNA promoters

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8 July 2018

Activation of p53 promotes renal injury in acute aristolochic acid nephropathy

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Modulation of microRNA processing by p53

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8 July 2018

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

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Regulation of TGF-beta signaling by Smad7.

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8 July 2018

Soluble HB-EGF induces epithelial-to-mesenchymal transition in inner medullary collecting duct cells by upregulating Snail-2.

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8 July 2018

Most mammalian mRNAs are conserved targets of microRNAs

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8 July 2018

SMAD proteins control DROSHA-mediated microRNA maturation

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8 July 2018

The identification of microRNAs in a genomically unstable region of human chromosome 8q24.

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8 July 2018

Diabetic nephropathy: mechanisms of renal disease progression

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Amplification of PVT1 contributes to the pathophysiology of ovarian and breast cancer.

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8 July 2018

Variants in the plasmacytoma variant translocation gene (PVT1) are associated with end-stage renal disease attributed to type 1 diabetes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808414

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MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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Identification of PVT1 as a candidate gene for end-stage renal disease in type 2 diabetes using a pooling-based genome-wide single nucleotide polymorphism association study

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3-Phosphoinositide-dependent PDK1 negatively regulates transforming growth factor-beta-induced signaling in a kinase-dependent manner through physical interaction with Smad proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808414

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Processing of intronic microRNAs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3808414

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siRNA in human cells selectively localizes to target RNA sites

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Regulation of transforming growth factor-beta signaling and PDK1 kinase activity by physical interaction between PDK1 and serine-threonine kinase receptor-associated protein

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Plasminogen activator inhibitor-1 and diabetic nephropathy.

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1 reference

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

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Reactive oxygen species and matrix remodeling in diabetic kidney

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8 July 2018

Reactive oxygen species-regulated signaling pathways in diabetic nephropathy

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8 July 2018

Extracellular matrix metabolism in diabetic nephropathy

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8 July 2018

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A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

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Transforming growth factor beta contributes to progressive diabetic nephropathy

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Cellular basis of diabetic nephropathy: II. The transforming growth factor-beta system and diabetic nephropathy lesions in type 1 diabetes

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21 January 2018

Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney.

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Pathway studio—the analysis and navigation of molecular networks

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12 December 2020

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SMADs stimulate miRNA processing

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based on heuristic

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Identifiers

10.1371/JOURNAL.PONE.0077468

1 reference

Europe PubMed Central

5 August 2017

2013PLoSO...877468A

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1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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