(Q35041304)

6 August 2017

title

Genome-wide association study of survival from sepsis due to pneumonia: an observational cohort study (English)

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genome-wide association study

6 August 2017

main subject

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14

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7

Jean-Daniel Chiche

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Emma E Davenport

Emma E Davenport

10

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Tom Parks

Tom Parks

8

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Anthony Gordon

Anthony C Gordon

3

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Michael Steffens

Michael Steffens

5

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Charles Mein

Charles Mein

17

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Julian C Knight

Julian C Knight

32

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Mark Caulfield

Mark J Caulfield

16

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Jordi Rello

Jordi Rello

25

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Adrian V. S. Hill

37

Adrian V S Hill

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Peter Lichtner

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Thomas F Wienker

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Katherine S Elliott

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30

Konrad Reinhart

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Anna Rautanen

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Tara C Mills

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Paula Hutton

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Rosamond Nuamah

6

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Stephen J Chapman

9

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Julian Bion

12

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Frank Bloos

18

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Ilona Bobek

19

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Paolo Cotogni

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Vladimir Sramek

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Silver Sarapuu

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Makbule Kobilay

23

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V Marco Ranieri

24

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Gonzalo Sirgo

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Yoram G Weiss

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Stefan Russwurm

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E Marion Schneider

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Paul A H Holloway

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Chris S Garrard

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James A Russell

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Keith R Walley

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Frank Stüber

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Charles J Hinds

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ESICM/ECCRN GenOSept Investigators

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6 August 2017

publication date

18 December 2014

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The Lancet. Respiratory medicine

6 August 2017

published in

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6 August 2017

volume

3

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6 August 2017

issue

1

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6 August 2017

page(s)

53-60

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describes a project that uses

6 August 2017

genome-wide association study

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Severe sepsis and septic shock

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Short- and long-term mortality in patients with community-acquired severe sepsis and septic shock

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

BCL2 genetic variants are associated with acute kidney injury in septic shock*

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

The function of neutrophils in sepsis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Human genetic susceptibility to infectious disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Five years of GWAS discovery

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Critical care and the global burden of critical illness in adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Long-term mortality and quality of life in sepsis: a systematic review

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Vasopressin versus norepinephrine infusion in patients with septic shock.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

A systematic review of the quality of genetic association studies in human sepsis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Absence of Fer protein tyrosine kinase exacerbates endotoxin induced intestinal epithelial barrier dysfunction in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Polymorphisms in CD14, mannose-binding lectin, and Toll-like receptor-2 are associated with increased prevalence of infection in critically ill adults

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

TNF and TNFR polymorphisms in severe sepsis and septic shock: a prospective multicentre study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

The epidemiology of sepsis in the United States from 1979 through 2000

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Fer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Genetics of susceptibility to human infectious disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Efficacy and safety of recombinant human activated protein C for severe sepsis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Role of genetic resistance in invasive pneumococcal infection: identification and study of susceptibility and resistance in inbred mouse strains

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

-308 tumor necrosis factor (TNF) polymorphism is not associated with survival in severe sepsis and is unrelated to lipopolysaccharide inducibility of the human TNF promoter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Nuclear and cytoplasmic location of the FER tyrosine kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Benchmarking the incidence and mortality of severe sepsis in the United States

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Beyond single-marker analyses: mining whole genome scans for insights into treatment responses in severe sepsis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Nationwide trends of severe sepsis in the 21st century (2000-2007).

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4314768

Genetic and environmental influences on premature death in adult adoptees

9 December 2018

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

MANNOSE-BINDING LECTIN POLYMORPHISMS IN SEVERE SEPSIS: RELATIONSHIP TO LEVELS, INCIDENCE, AND OUTCOME

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

The ACCP-SCCM consensus conference on sepsis and organ failure.

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

Interleukin-10 haplotype associated with increased mortality in critically ill patients with sepsis from pneumonia but not in patients with extrapulmonary sepsis

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

1 reference

https://api.crossref.org/works/10.1016%2FS2213-2600%2814%2970290-5

7 January 2021

10.1016/S2213-2600(14)70290-5

Identifiers

DOI

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6 August 2017

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6 August 2017

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