(Q35055252)

6 August 2017

FutureTox II: in vitro data and in silico models for predictive toxicology (English)

1 reference

6 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Thomas B Knudsen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Miriam Sander

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Edward W Carney

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Nancy G Doerrer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

David L Eaton

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Suzanne Compton Fitzpatrick

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Kenneth L Hastings

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Donna L Mendrick

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Raymond R Tice

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paul B Watkins

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Maurice Whelan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

1 reference

1 February 2015

1 reference

6 August 2017

Toxicological Sciences

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

256-267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity.

1 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Systems toxicology: from basic research to risk assessment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Data set modelability by QSAR

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

FutureTox: building the road for 21st century toxicology and risk assessment practices

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

The adverse outcome pathway concept: a pragmatic tool in toxicology.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Improving the human hazard characterization of chemicals: a Tox21 update

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Cell engineering with synthetic messenger RNA.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Addressing human variability in next-generation human health risk assessments of environmental chemicals

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Multi-scale modeling of tissues using CompuCell3D

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

The genome architecture of the Collaborative Cross mouse genetic reference population

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Disruption of embryonic vascular development in predictive toxicology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Identification and characterization of adverse effects in 21st century toxicology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Predicting drug-induced hepatotoxicity using QSAR and toxicogenomics approaches

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Adverse outcome pathways and ecological risk assessment: bridging to population-level effects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

The vision of toxicity testing in the 21st century: moving from discussion to action

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Toxicity testing in the 21st century: using the new toxicity testing paradigm to create a taxonomy of adverse effects

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Endless possibilities: stem cells and the vision for toxicology testing in the 21st century

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

A 21st century paradigm for evaluating the health hazards of nanoscale materials?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Pragmatic challenges for the vision of toxicity testing in the 21st century in a regulatory context: another Ames test? ...or a new edition of "the Red Book"?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Toxicology. Transforming environmental health protection

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

The Connectivity Map: a new tool for biomedical research

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

A method for high-throughput gene expression signature analysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4318934

Toxicity testing in the 21st century: a view from the chemical industry.

8 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU234

Ca²⁺ channel activators reveal differential L-type Ca²⁺ channel pharmacology between native and stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU234

Temporal concordance between apical and transcriptional points of departure for chemical risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU234

Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU234

Defining and modeling known adverse outcome pathways: Domoic acid and neuronal signaling as a case study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFU234

Serious adverse drug events reported to the Food and Drug Administration, 1998-2005

21 January 2018

1 reference

12 December 2020

Toxicity testing in the 21st century: a view from the pharmaceutical industry

1 reference

12 December 2020

Revolution dawning in cardiotoxicity testing

1 reference

12 December 2020

Erratum: "Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity"

1 reference

12 December 2020

Identifiers

DOI

10.1093/TOXSCI/KFU234

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25628403%20AND%20SRC:MED&resulttype=core&format=json