(Q35055467)

6 August 2017

title

Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure (English)

1 reference

6 August 2017

Bart C De Jonghe

1

1 reference

6 August 2017

Matthew R Hayes

2

1 reference

6 August 2017

Ryoichi Banno

3

1 reference

6 August 2017

Karolina P Skibicka

4

1 reference

6 August 2017

Derek J Zimmer

5

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6 August 2017

Kerisha A Bowen

6

1 reference

6 August 2017

Theresa M Leichner

7

1 reference

6 August 2017

Amber L Alhadeff

8

1 reference

6 August 2017

Scott E Kanoski

9

1 reference

6 August 2017

Nicole E Cyr

10

1 reference

6 August 2017

Eduardo A Nillni

11

1 reference

6 August 2017

Harvey J Grill

12

1 reference

6 August 2017

Kendra K Bence

13

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6 August 2017

publication date

15 March 2011

1 reference

American Journal of Physiology - Endocrinology and Metabolism

6 August 2017

published in

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6 August 2017

volume

300

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6 August 2017

issue

6

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6 August 2017

page(s)

E1002-11

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Leptin amplifies the action of thyrotropin-releasing hormone in the solitary nucleus: an in vitro calcium imaging study

6 August 2017

cites work

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Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits

8 July 2018

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8 July 2018

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PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Hypothalamic and hindbrain melanocortin receptors contribute to the feeding, thermogenic, and cardiovascular action of melanocortins

8 July 2018

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8 July 2018

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Neuronal protein tyrosine phosphatase 1B deficiency results in inhibition of hypothalamic AMPK and isoform-specific activation of AMPK in peripheral tissues

8 July 2018

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Leptin-dependent control of glucose balance and locomotor activity by POMC neurons.

8 July 2018

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Leptin receptor signaling and the regulation of mammalian physiology

8 July 2018

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Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance

8 July 2018

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Hindbrain leptin stimulation induces anorexia and hyperthermia mediated by hindbrain melanocortin receptors

8 July 2018

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8 July 2018

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8 July 2018

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Effects of maternal cold exposure and nutrient restriction on the ghrelin receptor, the GH-IGF axis, and metabolic regulation in the postnatal ovine liver.

8 July 2018

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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

8 July 2018

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Polymorphisms within the protein tyrosine phosphatase 1B (PTPN1) gene promoter: functional characterization and association with type 2 diabetes and related metabolic traits

8 July 2018

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PTP1B as a drug target: recent developments in PTP1B inhibitor discovery

8 July 2018

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Leptin is required for uncoupling protein-1-independent thermogenesis during cold stress.

8 July 2018

1 reference

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Absence of ghrelin protects against early-onset obesity

8 July 2018

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Mice lacking ghrelin receptors resist the development of diet-induced obesity

8 July 2018

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Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility

8 July 2018

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Leptin receptor signaling and the regulation of mammalian physiology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Thyroid hormone and uncoupling proteins.

8 July 2018

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Protein tyrosine phosphatase 1B: a novel target for type 2 diabetes and obesity

8 July 2018

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PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity

8 July 2018

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Brown fat thermogenesis in cold-acclimated rats is not abolished by the suppression of thyroid function

8 July 2018

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Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B.

8 July 2018

1 reference

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PTP1B regulates leptin signal transduction in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

A single nucleotide polymorphism in protein tyrosine phosphatase PTP-1B is associated with protection from diabetes or impaired glucose tolerance in Oji-Cree

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Obesity and insulin resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Central leptin regulates the UCP1 and ob genes in brown and white adipose tissue via different beta-adrenoceptor subtypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Induction of uncoupling protein expression in brown and white adipose tissue by leptin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Effects of the obese gene product on body weight regulation in ob/ob mice

8 July 2018

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Mitochondrial uncoupling protein from mouse brown fat. Molecular cloning, genetic mapping, and mRNA expression

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

8 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Neuronal PTP1B regulates body weight, adiposity and leptin action.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Sexually different actions of leptin in proopiomelanocortin neurons to regulate glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Uncoupling protein 2 mRNA expression and respiratory parameters in Kupffer cells isolated from euthyroid and hyperthyroid rat livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Brainstem melanocortin 3/4 receptor stimulation increases uncoupling protein gene expression in brown fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

Leptin induction of UCP1 gene expression is dependent on sympathetic innervation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3118594

Thermogenic defect in pre-obese ob/ob mice

25 October 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00639.2010

UCP1-independent thermogenesis in white adipose tissue of cold-acclimated Ucp1-/- mice

21 January 2018

1 reference

12 December 2020

Role of the Central Melanocortin Circuitry in Adaptive Thermogenesis of Brown Adipose Tissue

1 reference

12 December 2020

Thermogenesis in diabetes-obesity syndromes in mutant mice

1 reference

12 December 2020

Role of sympathetic innervation in brown adipocyte proliferation

1 reference

12 December 2020

Induction of UCP2 mRNA by thyroid hormones in rat heart

1 reference

12 December 2020

Ontogeny of iodothyronine deiodinases in human liver

1 reference

12 December 2020

Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold

1 reference

12 December 2020

10.1152/AJPENDO.00639.2010

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference