(Q35056063)

6 August 2017

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title

PTP1B inhibitors as potential therapeutics in the treatment of type 2 diabetes and obesity (English)

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6 August 2017

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Zhong-Yin Zhang

1

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6 August 2017

Seung-Yub Lee

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Expert Opinion on Investigational Drugs

6 August 2017

published in

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6 August 2017

volume

12

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6 August 2017

issue

2

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6 August 2017

page(s)

223-233

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Signaling--2000 and beyond

6 August 2017

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1 reference

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Deconstructing type 2 diabetes

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GSK3 takes centre stage more than 20 years after its discovery

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Protein tyrosine phosphatase 1B: a potential leptin resistance factor of obesity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Substrate specificity of the protein tyrosine phosphatases

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.12.2.223

Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition

21 January 2018

1 reference

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Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole-containing inhibitor with cellular activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.2.223

Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B

21 January 2018

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Steric hindrance as a basis for structure-based design of selective inhibitors of protein-tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.2.223

Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.2.223

Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.12.2.223

10.1517/13543784.12.2.223

21 January 2018

Identifiers

DOI

1 reference

6 August 2017

1 reference