(Q40010334)

16 September 2017

1 reference

title

Leptin receptor signaling and the regulation of mammalian physiology (English)

1 reference

16 September 2017

0 references

E C Villanueva

1

1 reference

PMCID

2648306

16 September 2017

M G Myers

series ordinal

2

1 reference

PMCID

2648306

16 September 2017

language of work or name

English

0 references

publication date

1 December 2008

1 reference

International Journal of Obesity

16 September 2017

1 reference

16 September 2017

32 Suppl 7

1 reference

16 September 2017

S8-12

1 reference

https://scigraph.springernature.com/pub.10.1038/ijo.2008.232

16 September 2017

0 references

cites work

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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

22 September 2017

1 reference

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Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice

22 September 2017

1 reference

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The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms

22 September 2017

1 reference

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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

22 September 2017

1 reference

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Nuclear translocation of the transcription factor STAT5 in the rat brain after systemic leptin administration

22 September 2017

1 reference

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The growing role of mTOR in neuronal development and plasticity.

22 September 2017

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Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals

22 September 2017

1 reference

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Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance

22 September 2017

1 reference

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Leptin receptor signaling and action in the central nervous system

22 September 2017

1 reference

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Central nervous system control of food intake and body weight

22 September 2017

1 reference

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Leptin regulation of the mesoaccumbens dopamine pathway.

22 September 2017

1 reference

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Leptin receptor signaling in midbrain dopamine neurons regulates feeding

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

22 September 2017

1 reference

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Hypothalamic mTOR signaling regulates food intake

22 September 2017

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Prevalence of overweight and obesity in the United States, 1999-2004

22 September 2017

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Stat5a/b are essential for normal lymphoid development and differentiation

22 September 2017

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Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

PI3K integrates the action of insulin and leptin on hypothalamic neurons

22 September 2017

1 reference

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Monogenic obesity in humans

22 September 2017

1 reference

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Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.

22 September 2017

1 reference

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Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

The role of leptin receptor signaling in feeding and neuroendocrine function

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Lifetime Risk for Diabetes Mellitus in the United States

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Intracellular signalling. Key enzyme in leptin-induced anorexia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Selective deletion of leptin receptor in neurons leads to obesity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Central nervous system control of food intake

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

The role of SOCS-3 in leptin signaling and leptin resistance

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Unraveling the central nervous system pathways underlying responses to leptin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

From lesions to leptin: hypothalamic control of food intake and body weight.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin receptor long-form splice-variant protein expression in neuron cell bodies of the brain and co-localization with neuropeptide Y mRNA in the arcuate nucleus.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin and the regulation of body weight in mammals

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Distributions of leptin receptor mRNA isoforms in the rat brain

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Congenital leptin deficiency is associated with severe early-onset obesity in humans

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Abnormal splicing of the leptin receptor in diabetic mice

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Absence of mutations in the human OB gene in obese/diabetic subjects

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Activation of downstream signals by the long form of the leptin receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Complexity of the TOR signaling network

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertility

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Regulation of Jak kinases by intracellular leptin receptor sequences.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Protein synthesis during LTP: linking synaptic activity to translation

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Divergent roles of SHP-2 in ERK activation by leptin receptors

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2648306

Leading causes of death in the United States

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19136996

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/IJO.2008.232

1 reference

16 September 2017

1 reference

16 September 2017

1 reference

PMCID

2648306