(Q40088322)

17 September 2017

The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms (English)

1 reference

17 September 2017

5

Heike Münzberg

1 reference

17 September 2017

Yusong Gong

1

1 reference

17 September 2017

Ryoko Ishida-Takahashi

2

1 reference

17 September 2017

Eneida C Villanueva

3

1 reference

17 September 2017

Diane C Fingar

4

1 reference

17 September 2017

Martin G Myers

6

1 reference

17 September 2017

language of work or name

English

0 references

publication date

28 August 2007

1 reference

Journal of Biological Chemistry

17 September 2017

1 reference

17 September 2017

282

1 reference

17 September 2017

42

1 reference

17 September 2017

31019-31027

1 reference

Prevalence of overweight and obesity in the United States, 1999-2004

17 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Lifetime Risk for Diabetes Mellitus in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Cellular warriors at the battle of the bulge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Unraveling the central nervous system pathways underlying responses to leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Monogenic human obesity syndromes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin and the regulation of body weight in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin receptor signaling and the regulation of mammalian physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Identifying hypothalamic pathways controlling food intake, body weight, and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Role of leptin in the neuroendocrine response to fasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Selective deletion of leptin receptor in neurons leads to obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

21 January 2018

The many lives of leptin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin receptor action and mechanisms of leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Activation of downstream signals by the long form of the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Divergent roles of SHP-2 in ERK activation by leptin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Feedback inhibition of leptin receptor/Jak2 signaling via Tyr1138 of the leptin receptor and suppressor of cytokine signaling 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Defective STAT signaling by the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Hypothalamic mTOR signaling regulates food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin and tumor necrosis factor-alpha induce the tyrosine phosphorylation of signal transducer and activator of transcription proteins in the hypothalamus of normal rats in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

General nature of the STAT3-activated anti-inflammatory response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Regulation of Jak kinases by intracellular leptin receptor sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin receptor signaling and action in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Functional roles of STAT family proteins: lessons from knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

A complex interaction pattern of CIS and SOCS2 with the leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702838200

21 January 2018

Identifiers

DOI

10.1074/JBC.M702838200

1 reference

17 September 2017

1 reference