(Q35056015)

6 August 2017

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title

Cyclin-dependent protein kinases as therapeutic drug targets for antimalarial drug development (English)

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6 August 2017

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Norman C Waters

1

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6 August 2017

Jeanne A Geyer

series ordinal

2

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6 August 2017

language of work or name

English

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publication date

1 February 2003

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Expert Opinion on Therapeutic Targets

6 August 2017

published in

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6 August 2017

volume

7

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6 August 2017

issue

1

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6 August 2017

page(s)

7-17

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Combating malaria in Africa

6 August 2017

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1 reference

https://api.crossref.org/works/10.1517%2F14728222.7.1.7

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Pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: what next?

21 January 2018

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Mechanisms of resistance of Plasmodium falciparum to antimalarial drugs

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An overview of chemotherapeutic targets for antimalarial drug discovery

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Discovering novel chemotherapeutic drugs for the third millennium

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Properties and potential-applications of chemical inhibitors of cyclin-dependent kinases

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Cyclin-dependent kinases: engines, clocks, and microprocessors

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Principles of CDK regulation

21 January 2018

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

21 January 2018

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Crystal structure of cyclin-dependent kinase 2

21 January 2018

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Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

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Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

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Thio- and oxoflavopiridols, cyclin-dependent kinase 1-selective inhibitors: synthesis and biological effects.

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Pfcrk-1, a developmentally regulated cdc2-related protein kinase of Plasmodium falciparum.

21 January 2018

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Isolation and expression of a gene specifying a cdc2-like protein kinase from the human malaria parasite Plasmodium falciparum

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21 January 2018

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Cyclin H activation and drug susceptibility of the Pfmrk cyclin dependent protein kinase from Plasmodium falciparum

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21 January 2018

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KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity

21 January 2018

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Influence of human p16(INK4) and p21(CIP1) on the in vitro activity of recombinant Plasmodium falciparum cyclin-dependent protein kinases

21 January 2018

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Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

21 January 2018

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Structural basis of cyclin-dependent kinase activation by phosphorylation

21 January 2018

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Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

21 January 2018

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A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues

21 January 2018

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21 January 2018

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21 January 2018

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Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein

21 January 2018

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Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis

21 January 2018

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Preclinical and clinical development of cyclin-dependent kinase modulators

21 January 2018

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Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors

21 January 2018

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Structure-based design of parasitic protease inhibitors

21 January 2018

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In vitro antimalarial activity of chalcones and their derivatives

21 January 2018

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Antimalarial alkoxylated and hydroxylated chalcones [corrected]: structure-activity relationship analysis

21 January 2018

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Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14728222.7.1.7

1 reference

6 August 2017

1 reference