(Q35058921)

6 August 2017

1 reference

title

Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities (English)

1 reference

6 August 2017

1 reference

Joel A Swanson

2

1 reference

ORCID Public Data File 2021

author name string

Go Saito

series ordinal

1

1 reference

PubMed ID

12564977

6 August 2017

Kyung-Dall Lee

series ordinal

3

1 reference

PubMed ID

12564977

6 August 2017

language of work or name

English

0 references

publication date

1 February 2003

1 reference

Advanced Drug Delivery Reviews

6 August 2017

1 reference

6 August 2017

55

1 reference

6 August 2017

2

1 reference

6 August 2017

199-215

1 reference

Receptor-mediated and enzyme-dependent targeting of cytotoxic anticancer drugs

6 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Targeted drug conjugates: principles and progress

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Penetration of protein toxins into cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Preparation of protein conjugates via intermolecular disulfide bond formation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Chimeric toxins: Toxic, disulfide-linked conjugate of concanavalin A with fragment A from diphtheria toxin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Oxidized redox state of glutathione in the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Physiological functions of thioredoxin and thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Thioredoxin and thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Dissecting the mechanism of protein disulfide isomerase: catalysis of disulfide bond formation in a model peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

1 reference

7 January 2021

Glutathione deficiency produced by inhibition of its synthesis, and its reversal; Applications in research and therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Presence of closely spaced protein thiols on the surface of mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Protein disulfide isomerase: the multifunctional redox chaperone of the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide Isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Protein disulfide isomerase mediates integrin-dependent adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Secretion, surface localization, turnover, and steady state expression of protein disulfide isomerase in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Localization of protein disulfide isomerase on plasma membranes of rat exocrine pancreatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

One molecule of diphtheria toxin fragment A introduced into a cell can kill the cell

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

A site-directed mutagenesis analysis of tNOX functional domains

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide-thiol oxidoreductase with protein disulfide-thiol interchange activity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Differential response of the NADH oxidase of plasma membranes of rat liver and hepatoma and HeLa cells to thiol reagents

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Thioredoxin expression and localization in human cell lines: detection of full-length and truncated species

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Antigen unfolding and disulfide reduction in antigen presenting cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Processing and reactivity of T cell epitopes containing two cysteine residues from hen egg-white lysozyme (HEL74-90)

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Measurement of phagosome-lysosome fusion and phagosomal pH.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Reduction of disulfide bonds during antigen processing: evidence from a thiol-dependent insulin determinant

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Disulphide reduction in lysosomes. The role of cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

A cysteine-specific lysosomal transport system provides a major route for the delivery of thiol to human fibroblast lysosomes: possible role in supporting lysosomal proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Mechanisms and catalysts of disulfide bond formation in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Multiple species express thiol oxidoreductases related to GILT

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Defective antigen processing in GILT-free mice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Thioredoxin reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Eradication of large colon tumor xenografts by targeted delivery of maytansinoids

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Chemical construction of immunotoxins

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

(6-Maleimidocaproyl)hydrazone of doxorubicin--a new derivative for the preparation of immunoconjugates of doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Selective tumor sensitization to taxanes with the mAb-drug conjugate cBR96-doxorubicin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Protected thiol-polyethylene glycol: a new activated polymer for reversible protein modification

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

A diverse set of oligomeric class II MHC-peptide complexes for probing T-cell receptor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Tumor targeting using anti-her2 immunoliposomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Single chain Fv: a ligand in receptor-mediated gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Therapeutic antibody fragments with prolonged in vivo half-lives

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Rational design of a potent, long-lasting form of interferon: a 40 kDa branched polyethylene glycol-conjugated interferon alpha-2a for the treatment of hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Transferrin-polycation conjugates as carriers for DNA uptake into cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Delivery of antisense oligonucleotides using HPMA polymer: synthesis of A thiol polymer and its conjugation to water-soluble molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Covalent Protein−Oligonucleotide Conjugates for Efficient Delivery of Antisense Molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Application of membrane-active peptides for nonviral gene delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Dioleoylmelittin as a novel serum-insensitive reagent for efficient transfection of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Surface aggregation and membrane penetration by peptides: relation to pore formation and fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Evolutionary biology. Protamine wars

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Importance of glutathione in the acquisition and maintenance of sperm nuclear decondensing activity in maturing hamster oocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Monomolecular collapse of plasmid DNA into stable virus-like particles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Caged DNA does not aggregate in high ionic strength solutions

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Triggered intracellular activation of disulfide crosslinked polyelectrolyte gene delivery complexes with extended systemic circulation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

A potent new class of reductively activated peptide gene delivery agents

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Glutathione-sensitive stabilization of block copolymer micelles composed of antisense DNA and thiolated poly(ethylene glycol)-block-poly(L-lysine): a potential carrier for systemic delivery of antisense DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Targeted delivery and triggered release of liposomal doxorubicin enhances cytotoxicity against human B lymphoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Current status of pH-sensitive liposomes in drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface-grafted poly(ethylene glycol).

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cell-penetrating peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Trojan peptides: the penetratin system for intracellular delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cargo delivery kinetics of cell-penetrating peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Glutathione measurement in human plasma. Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Redox state of glutathione in human plasma.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

New detachable poly(ethylene glycol) conjugates: cysteine-cleavable lipopolymers regenerating natural phospholipid, diacyl phosphatidylethanolamine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Use of designed peptide linkers and recombinant hemoglobin mutants for drug delivery: in vitro release of an angiotensin II analog and kinetic modeling of delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

In vivo administration of lymphocyte-specific monoclonal antibodies in nonhuman primates. In vivo stability of disulfide-linked immunotoxin conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Treatment of refractory Hodgkin's lymphoma patients with an anti-CD25 ricin A-chain immunotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

New coupling reagents for the preparation of disulfide cross-linked conjugates with increased stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Role of Cross-Linking Agents in Determining the Biochemical and Pharmacokinetic Properties of Mgr6−Clavin Immunotoxins

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

An anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia. Choice of linker

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Polymer-drug conjugates, PDEPT and PELT: basic principles for design and transfer from the laboratory to clinic

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Preparation and in vitro cytotoxicity of a methotrexate-anti-MM46 monoclonal antibody conjugate via an oligopeptide spacer

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cytotoxicities of two disulfide-bond-linked conjugates of methotrexate with monoclonal anti-MM46 antibody

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2802%2900179-5

7 January 2021

10.1016/S0169-409X(02)00179-5

Identifiers

DOI

1 reference

6 August 2017

1 reference

PubMed ID

12564977