(Q35060404)

6 August 2017

The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy (English)

1 reference

6 August 2017

Yi-Je Chen

1

1 reference

6 August 2017

Jenny Lam

2

1 reference

6 August 2017

Clare R Gregory

3

1 reference

6 August 2017

Sonja Schrepfer

4

1 reference

6 August 2017

Heike Wulff

5

1 reference

6 August 2017

language of work or name

English

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publication date

29 November 2013

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6 August 2017

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6 August 2017

8

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6 August 2017

11

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6 August 2017

e81006

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Creative Commons Attribution 3.0 Unported

6 August 2017

start time

29 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

The intermediate conductance calcium-activated potassium channel KCa3.1 regulates vascular smooth muscle cell proliferation via controlling calcium-dependent signaling

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The potassium channel KCa3.1 as new therapeutic target for the prevention of obliterative airway disease

8 July 2018

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Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model.

8 July 2018

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Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels

8 July 2018

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NS6180, a new K(Ca) 3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease.

8 July 2018

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Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease

8 July 2018

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Therapeutic potential of KCa3.1 blockers: recent advances and promising trends

8 July 2018

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The KCa3.1 blocker TRAM-34 reduces infarction and neurological deficit in a rat model of ischemia/reperfusion stroke

8 July 2018

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Diverse morphologic manifestations of cardiac allograft vasculopathy: a pathologic study of 64 allograft hearts.

8 July 2018

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Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers

8 July 2018

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KV1.3: a new therapeutic target to control vascular smooth muscle cell proliferation

8 July 2018

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Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis

8 July 2018

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Voltage-gated potassium channels as therapeutic targets

8 July 2018

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The functional network of ion channels in T lymphocytes

8 July 2018

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Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

8 July 2018

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Orai1, a critical component of store-operated Ca2+ entry, is functionally associated with Na+/Ca2+ exchanger and plasma membrane Ca2+ pump in proliferating human arterial myocytes

8 July 2018

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The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

K+ channel modulators for the treatment of neurological disorders and autoimmune diseases

8 July 2018

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Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis.

8 July 2018

1 reference

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Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

8 July 2018

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Vascular remodeling in transplant vasculopathy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Targeting effector memory T cells with the small molecule Kv1.3 blocker PAP-1 suppresses allergic contact dermatitis

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Allograft vasculopathy versus atherosclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory T cells in autoimmune diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Blockade of the intermediate-conductance calcium-activated potassium channel as a new therapeutic strategy for restenosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Cold ischemia induces isograft arteriopathy, but does not augment allograft arteriopathy in non-immunosuppressed hosts

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Coronary arteriosclerosis after T-cell-mediated injury in transplanted mouse hearts: role of interferon-gamma.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3843675

The chemokine and chemokine receptor profile of infiltrating cells in the wall of arteries with cardiac allograft vasculopathy is indicative of a memory T-helper 1 response.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Prevention and inhibition but not reversion of chronic allograft vasculopathy by FK778.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Airway fibrosis in a mouse model of airway inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Genetic deficit of SK3 and IK1 channels disrupts the endothelium-derived hyperpolarizing factor vasodilator pathway and causes hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

The interaction between FK778 and tacrolimus in the prevention of rat cardiac allograft rejection is dose dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Significant reduction of acute cardiac allograft rejection by selective janus kinase-1/3 inhibition using R507 and R545.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Potassium channels and proliferation of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Characterization of ion channels involved in the proliferative response of femoral artery smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Dose-escalation study of ICA-17043 in patients with sickle cell disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Blockade of T-lymphocyte KCa3.1 and Kv1.3 channels as novel immunosuppression strategy to prevent kidney allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0081006

Kv1.3 channels as a potential target for immunomodulation of CD4+ CD28null T cells in patients with acute coronary syndrome

21 January 2018

1 reference

12 December 2020

Successful heterotopic heart transplantation in rat

1 reference

12 December 2020

Ras/MEK/ERK Up-regulation of the fibroblast KCa channel FIK is a common mechanism for basic fibroblast growth factor and transforming growth factor-beta suppression of myogenesis

1 reference

12 December 2020

The pathogenesis of coronary arteriosclerosis ("chronic rejection") in transplanted hearts

1 reference

12 December 2020

Factors contributing to the development of chronic rejection in heterotopic rat heart transplantation

1 reference

12 December 2020

Chronic rejection in rat aortic allografts. An experimental model for transplant arteriosclerosis

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0081006

Identifiers

DOI

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6 August 2017

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6 August 2017

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