(Q35063341)

English

Amyloid beta-mediated cell death of cultured hippocampal neurons reveals extensive Tau fragmentation without increased full-length tau phosphorylation

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Amyloid beta-mediated cell death of cultured hippocampal neurons reveals extensive Tau fragmentation without increased full-length tau phosphorylation (English)

1 reference

Europe PubMed Central

6 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Jack Reifert

1

1 reference

Europe PubMed Central

6 August 2017

DeeAnn Hartung-Cranston

2

1 reference

Europe PubMed Central

6 August 2017

Stuart C Feinstein

3

1 reference

Europe PubMed Central

6 August 2017

language of work or name

0 references

publication date

11 April 2011

1 reference

Europe PubMed Central

6 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

6 August 2017

286

1 reference

Europe PubMed Central

6 August 2017

23

1 reference

Europe PubMed Central

6 August 2017

20797-20811

1 reference

Europe PubMed Central

6 August 2017

Acetylation of microtubules influences their sensitivity to severing by katanin in neurons and fibroblasts

1 reference

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8 July 2018

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.

1 reference

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8 July 2018

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25-35): involvement of lipid rafts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

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8 July 2018

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

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8 July 2018

A beta oligomers - a decade of discovery

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

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8 July 2018

Sequential degradation of alphaII and betaII spectrin by calpain in glutamate or maitotoxin-stimulated cells

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8 July 2018

The role of tau phosphorylation in the pathogenesis of Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Inducible expression of Tau repeat domain in cell models of tauopathy: aggregation is toxic to cells but can be reversed by inhibitor drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates beta-amyloid-induced neurodegeneration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

1 reference

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8 July 2018

Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Cultured cell and transgenic mouse models for tau pathology linked to beta-amyloid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Tau phosphorylation in neuronal cell function and dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

1 reference

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8 July 2018

Caspase-mediated degeneration in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Modulation of microtubule dynamics by tau in living cells: implications for development and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Caspase cleavage of tau: linking amyloid and neurofibrillary tangles in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies

1 reference

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8 July 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Tau is essential to beta -amyloid-induced neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

The renaissance of GSK3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Changes in caspase expression in Alzheimer's disease: comparison with development and aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

m-Calpain (calcium-activated neutral proteinase) in Alzheimer's disease brains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Distribution of isoforms of the microtubule-associated protein tau in grey and white matter areas of human brain: a two-dimensional gelelectrophoretic analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Developmentally regulated expression of specific tau sequences

1 reference

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8 July 2018

Mechanisms of amyloid deposition in Alzheimer's disease.

1 reference

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8 July 2018

The molecular pathology of Alzheimer's disease

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8 July 2018

Alzheimer's disease: the amyloid cascade hypothesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121465

8 July 2018

Examination of phosphorylated tau protein as a PHF-precursor at early stage Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Proline-directed pseudo-phosphorylation at AT8 and PHF1 epitopes induces a compaction of the paperclip folding of Tau and generates a pathological (MC-1) conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Preparation and characterization of toxic Abeta aggregates for structural and functional studies in Alzheimer's disease research.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Increased membrane cholesterol might render mature hippocampal neurons more susceptible to beta-amyloid-induced calpain activation and tau toxicity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

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https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology

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21 January 2018

Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex

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https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment.

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21 January 2018

Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.

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21 January 2018

Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.234674

21 January 2018

Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death.

1 reference

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27 September 2018

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21482827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.234674

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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