(Q35063359)

English

Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Mapping the intermedilysin-human CD59 receptor interface reveals a deep correspondence with the binding site on CD59 for complement binding proteins C8alpha and C9 (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Michael W Parker

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Michael W Parker

7

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author name string

Stephanie E Wickham

1

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Eileen M Hotze

2

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Allison J Farrand

3

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Galina Polekhina

4

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Tracy L Nero

5

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Stephen Tomlinson

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Rodney K Tweten

8

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

language of work or name

0 references

publication date

20 April 2011

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

6 August 2017

286

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

20952-20962

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The structural basis for membrane binding and pore formation by lymphocyte perforin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Intermedilysin-receptor interactions during assembly of the pore complex: assembly intermediates increase host cell susceptibility to complement-mediated lysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

The MACPF/CDC family of pore-forming toxins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Functional and phylogenetic characterization of Vaginolysin, the human-specific cytolysin from Gardnerella vaginalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Version 1.2 of the Crystallography and NMR system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

A common fold mediates vertebrate defense and bacterial attack

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

High-resolution structures of bacterially expressed soluble human CD59

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Defining the CD59-C9 binding interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

CD59 blocks not only the insertion of C9 into MAC but inhibits ion channel formation by homologous C5b-8 as well as C5b-9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Identity of the residues responsible for the species-restricted complement inhibitory function of human CD59.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Rapid refinement of protein interfaces incorporating solvation: application to the docking problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Modelling protein docking using shape complementarity, electrostatics and biochemical information

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Mutational analysis of the active site and antibody epitopes of the complement-inhibitory glycoprotein, CD59

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Mapping the active site of CD59

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

VMD: visual molecular dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Structure of a soluble, glycosylated form of the human complement regulatory protein CD59

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Isolation of a tryptic fragment from Clostridium perfringens theta-toxin that contains sites for membrane binding and self-aggregation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Inhibition of homologous complement by CD59 is mediated by a species-selective recognition conferred through binding to C8 within C5b-8 or C9 within C5b-9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

The complement-inhibitory activity of CD59 resides in its capacity to block incorporation of C9 into membrane C5b-9

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

8 July 2018

Insights into the human CD59 complement binding interface toward engineering new therapeutics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.237446

21 January 2018

The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.237446

21 January 2018

Use of pair potentials across protein interfaces in screening predicted docked complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121471

27 September 2018

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.237446

21 January 2018

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.237446

21 January 2018

Protease-nicked theta-toxin of Clostridium perfringens, a new membrane probe with no cytolytic effect, reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21507937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory control of the terminal complement proteins at the surface of human endothelial cells: neutralization of a C5b-9 inhibitor by antibody to CD59

1 reference

https://pubmed.ncbi.nlm.nih.gov/21507937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-function relationships of the complement regulatory protein, CD59

1 reference

https://pubmed.ncbi.nlm.nih.gov/21507937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.237446

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

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