(Q35064991)

6 August 2017

title

Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria (English)

1 reference

ORCID Public Data File 2021

6 August 2017

1 reference

1 reference

author name string

F Mollinedo

1

1 reference

6 August 2017

M Fernández

2

1 reference

6 August 2017

V Hornillos

3

1 reference

6 August 2017

J Delgado

4

1 reference

6 August 2017

F Amat-Guerri

5

1 reference

6 August 2017

A U Acuña

6

1 reference

6 August 2017

T Nieto-Miguel

7

1 reference

6 August 2017

J A Villa-Pulgarín

8

1 reference

6 August 2017

C González-García

9

1 reference

6 August 2017

V Ceña

10

1 reference

6 August 2017

C Gajate

11

1 reference

6 August 2017

publication date

19 May 2011

1 reference

6 August 2017

published in

Cell Death and Disease

1 reference

6 August 2017

volume

2

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6 August 2017

page(s)

e158

1 reference

Methyl-beta-cyclodextrin induces mitochondrial cholesterol depletion and alters the mitochondrial structure and bioenergetics

6 August 2017

cites work

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8 July 2018

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Cardiolipin-enriched raft-like microdomains are essential activating platforms for apoptotic signals on mitochondria.

8 July 2018

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8 July 2018

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Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.

8 July 2018

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8 July 2018

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ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor

8 July 2018

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ATP-binding cassette (ABC) transporters mediate nonvesicular, raft-modulated sterol movement from the plasma membrane to the endoplasmic reticulum.

8 July 2018

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Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis

8 July 2018

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Superoxide anions mediate veratridine-induced cytochrome c release and caspase activity in bovine chromaffin cells

8 July 2018

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Intracellular cholesterol transport

8 July 2018

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Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells

8 July 2018

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Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis

8 July 2018

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Intracellular triggering of Fas, independently of FasL, as a new mechanism of antitumor ether lipid-induced apoptosis

8 July 2018

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8 July 2018

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Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L).

8 July 2018

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Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.

8 July 2018

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Interaction of non-classical detergents with the mitochondrial porin. A new purification procedure and characterization of the pore-forming unit

8 July 2018

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In vitro and In vivo selective antitumor activity of Edelfosine against mantle cell lymphoma and chronic lymphocytic leukemia involving lipid rafts

8 July 2018

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Association of fission proteins with mitochondrial raft-like domains.

27 September 2018

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27 September 2018

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Edelfosine is incorporated into rafts and alters their organization

27 September 2018

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Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells.

27 September 2018

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Lipid microdomains contribute to apoptosis-associated modifications of mitochondria in T cells.

27 September 2018

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The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells

27 September 2018

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Involvement of mitochondria and caspase-3 in ET-18-OCH(3)-induced apoptosis of human leukemic cells.

27 September 2018

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Cytotoxicity of an Anti-cancer Lysophospholipid through Selective Modification of Lipid Raft Composition

27 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2011.41

Differential Targets and Subcellular Localization of Antitumor Alkyl-lysophospholipid in LeukemicVersusSolid Tumor Cells

21 January 2018

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Mitochondrial contact sites. Lipid composition and dynamics

21 January 2018

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12 December 2020

Intracellular cholesterol transport

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12 December 2020

Role of lipid transfer proteins in the abnormal lipid content of Morris hepatoma mitochondria and microsomes

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12 December 2020

Modulation of the mitochondrial permeability transition pore. Effect of protons and divalent cations

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12 December 2020

Identifiers

DOI

10.1038/CDDIS.2011.41

1 reference

6 August 2017

1 reference

6 August 2017

1 reference