(Q35067403)

6 August 2017

title

CCAAT/enhancer-binding protein homologous (CHOP) protein promotes carcinogenesis in the DEN-induced hepatocellular carcinoma model (English)

1 reference

6 August 2017

main subject

hepatocellular carcinoma

1 reference

1 reference

Viviana Scaiewicz

1

1 reference

6 August 2017

Avital Nahmias

2

1 reference

6 August 2017

Raymond T Chung

3

1 reference

6 August 2017

Tobias Mueller

4

1 reference

6 August 2017

Boaz Tirosh

5

1 reference

6 August 2017

Oren Shibolet

6

1 reference

6 August 2017

language of work or name

English

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publication date

5 December 2013

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6 August 2017

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6 August 2017

volume

8

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6 August 2017

issue

12

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6 August 2017

page(s)

e81065

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Creative Commons Attribution 3.0 Unported

6 August 2017

copyright license

start time

5 December 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3855209/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

8 July 2018

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The clinical significance of the CD163+ and CD68+ macrophages in patients with hepatocellular carcinoma.

8 July 2018

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p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

C/EBP homologous protein (CHOP) contributes to suppression of metabolic genes during endoplasmic reticulum stress in the liver

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Distinct cytoplasmic and nuclear functions of the stress induced protein DDIT3/CHOP/GADD153

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Stress management at the ER: regulators of ER stress-induced apoptosis

8 July 2018

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Cyclooxygenase 2 and Prostaglandin E2 are not Involved in N-Nitrosodiethylamine-Initiated Early Rat Hepatocarcinogenesis

8 July 2018

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Role of tumor-associated macrophages in the progression of hepatocellular carcinoma

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

8 July 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.

8 July 2018

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Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas

8 July 2018

1 reference

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PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.

8 July 2018

1 reference

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The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Molecular symbiosis of CHOP and C/EBP beta isoform LIP contributes to endoplasmic reticulum stress-induced apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Transcriptional regulation of VEGF-A by the unfolded protein response pathway

8 July 2018

1 reference

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Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

8 July 2018

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Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

8 July 2018

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Signal integration in the endoplasmic reticulum unfolded protein response

8 July 2018

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Paradoxical roles of the immune system during cancer development

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Roles of CHOP/GADD153 in endoplasmic reticulum stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Bcl-2 expression inhibits liver carcinogenesis and delays the development of proliferating foci

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Regulated translation initiation controls stress-induced gene expression in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Tumor-promoting and hepatocarcinogenic effects of 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene (TCPOBOP) in DBA/2NCr and C57BL/6NCr mice and an apparent promoting effect on nasal cavity tumors but not on hepatocellular tumors in F344/NCr rats initiate

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

International trends in liver cancer incidence rates

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Interferon-gamma-mediated hepatocarcinogenesis in mice treated with diethylnitrosamine

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Increased GADD153 gene expression during iron chelation-induced apoptosis in Jurkat T-lymphocytes

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3855209

Tumor-associated macrophage promotes tumor progression via STAT3 signaling in hepatocellular carcinoma

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24339898

12 December 2020

inferred from PubMed ID database lookup

Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24339898

12 December 2020

inferred from PubMed ID database lookup

Prognostic value of tumor-associated macrophage count in human bladder cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24339898

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0081065

1 reference

6 August 2017

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1 reference

6 August 2017

1 reference